Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Livia S. Machado"'
Autor:
David C. Hess, Irina Y Sazonova, Adviye Ergul, Daniel C. Wiley, Azza B. El-Remessy, Susan C. Fagan, Anna Kozak, Livia S. Machado, Jennifer L. Waller
Publikováno v:
Stroke. 40:3028-3033
Background and Purpose— New treatment strategies for acute ischemic stroke must be evaluated in the context of effective reperfusion. Minocycline is a neuroprotective agent that inhibits proteolytic enzymes and therefore could potentially both inac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfcbe310541dc3a06271b8aa7ec0d29c
https://doi.org/10.1161/strokeaha.109.556852
https://doi.org/10.1161/strokeaha.109.556852
Autor:
Daniel C. Wiley, Mohammed Abdelsaid, Azza B. El-Remessy, Susan C. Fagan, Livia S. Machado, Anna Kozak, Adviye Ergul, Maribeth H. Johnson, Hazem Elewa
Publikováno v:
Stroke. 40:1870-1876
Background and Purpose— We have shown that acute treatment with candesartan in an experimental model of stroke resulted in vascular protection and improved outcomes at 24 hours poststroke, but the mechanisms are unknown. We now examine effects of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4272bfdfa2f0f48191ce2eb20df4f229
https://doi.org/10.1161/strokeaha.108.537225
https://doi.org/10.1161/strokeaha.108.537225
Autor:
Vera Portik-Dobos, L. Creed Pettigrew, Susan C. Fagan, Wayne M. Clark, David C. Hess, Adviye Ergul, Livia S. Machado, Jeffrey A. Switzer, Jennifer L. Waller
Publikováno v:
Stroke. 42(9)
Background and Purpose— Plasma matrix metalloproteinase-9 levels predict posttissue plasminogen activator (tPA) hemorrhage. Methods— The authors investigated the effect of minocycline on plasma matrix metalloproteinase-9 in acute ischemic stroke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc5f6bad70fbfb64bf524a4f703d31fe
https://pubmed.ncbi.nlm.nih.gov/21903959
https://pubmed.ncbi.nlm.nih.gov/21903959
Autor:
Susan C. Fagan, David C. Hess, Adviye Ergul, Anna Kozak, Cesario V. Borlongan, Livia S. Machado
Publikováno v:
BMC Neuroscience, Vol 7, Iss 1, p 56 (2006)
BMC Neuroscience
BMC Neuroscience
Background Matrix metalloproteinases 2 and 9 (MMP-2 and MMP-9) are increased in the brain after experimental ischemic stroke in rats. These two proteases are involved with the degradation of the basal lamina and loss of stability of the blood brain b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dee1c97c9ef648bde014e6918d0c1e5
http://www.biomedcentral.com/1471-2202/7/56
http://www.biomedcentral.com/1471-2202/7/56
Publikováno v:
Pharmacotherapy. 26(4)
Minocycline is a widely used tetracycline antibiotic. It has been used for decades in the treatment of various gram-positive and gram-negative infections. More recently, minocycline has been shown to have neuroprotective properties in different anima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5cbe059f3af3b2259709b912414b5dd
https://pubmed.ncbi.nlm.nih.gov/16553511
https://pubmed.ncbi.nlm.nih.gov/16553511
Autor:
Anna Kozak, Susan C. Fagan, Adviye Ergul, Maribeth H. Johnson, Livia S. Machado, Alex K. Harris
Publikováno v:
BMC Neuroscience, Vol 6, Iss 1, p 49 (2005)
BMC Neuroscience
BMC Neuroscience
Background While gelatinase (MMP-2 and -9) activity is increased after focal ischemia/reperfusion injury in the brain, the relative contribution of neutrophils to the MMP activity and to the development of hemorrhagic transformation remains unknown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f457618fe958cc8004f176d0582b611
https://doi.org/10.1186/1471-2202-6-49
https://doi.org/10.1186/1471-2202-6-49
Autor:
Livia S. Machado, David M. Pollock, Elizabeth J. Hohnadel, Adviye Ergul, David C. Hess, Susan C. Fagan
Publikováno v:
Pharmacotherapy. 25(3)
The vascular events that happen during ischemic stroke worsen outcomes in patients by causing edema, hemorrhagic transformation, and general neurologic tissue compromise. In the past 2 decades, clinical trials in patients after ischemic stroke focuse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ae78c0977f53e2c6f65b1460b0bdc16
https://pubmed.ncbi.nlm.nih.gov/15843286
https://pubmed.ncbi.nlm.nih.gov/15843286