The hop-derived compounds xanthohumol, isoxanthohumol and 8-prenylnaringenin are tight-binding inhibitors of human aldo-keto reductases 1B1 and 1B10

Autor: Jan Moritz Seliger, Livia Misuri, Edmund Maser, Jan Hintzpeter

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 607-614 (2018)

Xanthohumol (XN), a prenylated chalcone unique to hops (Humulus lupulus) and two derived prenylflavanones, isoxanthohumol (IX) and 8-prenylnaringenin (8-PN) gained increasing attention as potential anti-diabetic and cancer preventive compounds. Two e

Externí odkaz: https://doaj.org/article/17e385b929014c069e2ded3fdeb02883

Zolfino landrace (Phaseolus vulgaris L.) from Pratomagno: general and specific features of a functional food

Autor: Francesco Balestri, Rossella Rotondo, Roberta Moschini, Mario Pellegrino, Mario Cappiello, Vito Barracco, Livia Misuri, Carlo Sorce, Andrea Andreucci, Antonella Del-Corso, Umberto Mura

Publikováno v: Food & Nutrition Research, Vol 60, Iss 0, Pp 1-11 (2016)

Background: The Zolfino bean is a variety of Phaseolus vulgaris, which is cultivated in a limited area of Tuscany, Italy, and is widely appreciated for its flavor and culinary uses. Objectives: A yellow Zolfino landrace cultivated in the Leccio-Regge

Externí odkaz: https://doaj.org/article/9350ad6885bb41d884606aa0dfaf7e86

The use of dimethylsulfoxide as a solvent in enzyme inhibition studies: the case of aldose reductase

Autor: Vito Barracco, Umberto Mura, Mario Cappiello, Livia Misuri, Francesco Balestri, Antonella Del-Corso, Roberta Moschini

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 1152-1158 (2017)
Journal of Enzyme Inhibition and Medicinal Chemistry

Aldose reductase (AR) is an enzyme devoted to cell detoxification and at the same time is strongly involved in the aetiology of secondary diabetic complications and the amplification of inflammatory phenomena. AR is subjected to intense inhibition st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb2609bd9ff9b15e6fe48ed8405dcb83
https://doaj.org/article/b0c0e69a53104b82a6a2b256f9ebcb5b