Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Livia, Fülöp"'
Autor:
Éva Bartus, Gábor Olajos, Ildikó Schuster, Zsolt Bozsó, Mária A. Deli, Szilvia Veszelka, Fruzsina R. Walter, Zsolt Datki, Zsolt Szakonyi, Tamás A. Martinek, Livia Fülöp
Publikováno v:
Molecules, Vol 23, Iss 10, p 2523 (2018)
Alzheimer’s disease is one of the most common chronic neurodegenerative disorders. Despite several in vivo and clinical studies, the cause of the disease is poorly understood. Currently, amyloid β (Aβ) peptide and its tendency to assemble into so
Externí odkaz:
https://doaj.org/article/4a8c18ce1d6c46f88628165bf8266cbe
Searching for improved mimetic peptides inhibitors preventing conformational transition of amyloid-β
Autor:
János, Gera, Titanilla, Szögi, Zsolt, Bozsó, Livia, Fülöp, Exequiel E, Barrera, Ana M, Rodriguez, Luciana, Méndez, Carina M L, Delpiccolo, Ernesto G, Mata, Federica, Cioffi, Kerensa, Broersen, Gabor, Paragi, Ricardo D, Enriz
Publikováno v:
Bioorganic chemistry. 81
A series of novel mimetic peptides were designed, synthesised and biologically evaluated as inhibitors of Aβ
Autor:
Ivan, Milenkovic, Tamara, Stojanovic, Eleonora, Aronica, Livia, Fülöp, Zsolt, Bozsó, Zoltán, Máté, Yuchio, Yanagawa, Homa, Adle-Biassette, Gert, Lubec, Gábor, Szabó, Tibor, Harkany, Gábor G, Kovács, Erik, Keimpema
Publikováno v:
Brain Structure & Function
The function, regulation and cellular distribution of GABAA receptor subunits have been extensively documented in the adult rodent brain and are linked to numerous neurological disorders. However, there is a surprising lack of knowledge on the cellul
Autor:
Xu Liu, Michael D. Menger, Robert Schomburg, Wenlin Hao, Yang Liu, Klaus Fassbender, Manolis Pasparakis, Livia Fülöp, Yann Decker
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 34(39)
Alzheimer's disease (AD) is characterized by extracellular amyloid-β (Aβ) deposits and microglia-dominated inflammatory activation. Innate immune signaling controls microglial inflammatory activities and Aβ clearance. However, studies examining in
Publikováno v:
European Journal of Organic Chemistry. 1998:2769-2773
The synthesis of novel disubstituted rubicenes 1a–k is described. Starting from 1,5-dichloroanthraquinone and aryllithium reagents 3, the diol adducts 4 are reduced and the resulting diarylanthracenes 5 are cyclized to afford the title compounds in
Publikováno v:
Journal of peptide science : an official publication of the European Peptide Society. 14(6)
CD and infrared spectroscopic studies were performed on (i) the inhibitory effects of equimolar quantities of LPFFD-OH and LPYFD-NH(2) on the time-dependent aggregation of amyloid beta-protein (Abeta) (1-42) and (ii) the beta-sheet-breaker effects of
Publikováno v:
Organic Letters; Dec2010, Vol. 12 Issue 23, p5584-5587, 4p