Výsledky vyhledávání

Sertoli cell PUMILIO proteins modulate mouse testis size through translational control of cell cycle regulators

Autor: Tingting, Zhao, Tianheng, Xiao, Dandan, Cao, Wenjuan, Xia, Liuze, Gao, Liping, Cheng, Min, Zang, Xin, Li, Eugene Yujun, Xu

Publikováno v: Biology of Reproduction. 107:135-147

Testis size determination is an important question of reproductive biology. Sertoli cells are known to be a key determinant of mammalian testis size but the underlying molecular mechanisms remain incompletely understood. Previously we showed that hig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d38ca3ff40c71fa4e001a2e1d273d0e
https://doi.org/10.1093/biolre/ioac118

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Circular RNAs from BOULE play conserved roles in protection against stress-induced fertility decline

Autor: Xu Liu, Wenjuan Xia, Chenwang Zhang, Liang Chen, Liping Cheng, Qinghua Shi, Ge Shan, Eugene Yujun Xu, Xiaolin Wang, Shuhui Chang, Juan Huang, Liuze Gao

Publikováno v: Science Advances. 6

Circular RNAs (circRNAs) are a large family of newly identified transcripts, and their physiological roles and evolutionary significance require further characterization. Here, we identify circRNAs generated from a conserved reproductive gene, Boule,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f89a8d788bfd8e8595b0a11dcaaaba25
https://doi.org/10.1126/sciadv.abb7426

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Essential requirement of mammalianPumiliofamily in embryonic development

Autor: Qinghua Shi, Eugene Yujun Xu, Baobao Geng, Liuze Gao, Zimeng Zheng, Mengyi Zhu, Shikun Zhang, Kaibo Lin, Wenjuan Xia

Publikováno v: Molecular Biology of the Cell

Mouse PUMILIO1 (PUM1) and PUMILIO2 (PUM2) belong to the PUF (Pumilio/FBF) family, a highly conserved RNA binding protein family whose homologues play critical roles in embryonic development and germ line stem cell maintenance in invertebrates. Howeve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95f6f641db4e6cafe6f2b8f0dcbf7443
https://doi.org/10.1091/mbc.e18-06-0369

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Highly conserved epigenetic regulation of BOULE and DAZL is associated with human fertility

Autor: Peng Xue, Xia Chen, Eugene Yujun Xu, Kaibo Lin, Xiaoyu Yang, Yifan Dai, Liuze Gao, Chenwang Zhang

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 30(10)

Separation of germ cells from somatic cells is a widespread feature of animal sexual reproduction, with a core set of germ cell factors conserved among diverse animals. It is not known what controls their conserved gonad-specific expression. Core com

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8beb0f5ff4acffe672fb96b66d6abf12
https://pubmed.ncbi.nlm.nih.gov/27358391

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