Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Liuya Wei"'
Autor:
Weiguo Song, Hekai Yang, Ying Wang, Shuzhen Chen, Wenda Zhong, Qian Wang, Wenshuo Ding, Guangzhao Xu, Chen Meng, Ying Liang, Zhe‐Sheng Chen, Shuhua Cao, Liuya Wei, Fahui Li
Publikováno v:
Advanced Science, Vol 11, Iss 30, Pp n/a-n/a (2024)
Abstract Multi‐drug resistance (MDR) is a major cause of cancer therapy failure. Photodynamic therapy (PDT) is a promising modality that can circumvent MDR and synergize with chemotherapies, based on the generation of reactive oxygen species (ROS)
Externí odkaz:
https://doaj.org/article/dfe4096d398d4ba78db0668db03a63d9
Autor:
Hekai Yang, Fahui Li, Shuzhen Chen, Shanshan Jin, Weiwei Chen, Wen Sun, Liuya Wei, Guangzhao Xu, Weiguo Song, Wenda Zhong
Publikováno v:
Materials & Design, Vol 237, Iss , Pp 112566- (2024)
The excessive production of reactive oxygen species (ROS) can damage the mitochondrial membrane and induce apoptosis, causing endoplasmic reticulum stress and triggering immunogenic cell death. Therefore, the combination of apoptosis and immunogenic
Externí odkaz:
https://doaj.org/article/fd4a3caef874460798227fb24b9d2435
Autor:
Lei Cao, Shuzhen Chen, Rainie Sun, Charles R. Ashby, Liuya Wei, Zoufang Huang, Zhe-Sheng Chen
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
The FDA granted orphan drug designation to darovasertib, a first-in-class oral, small molecular inhibitor of protein kinase C (PKC), for the treatment of uveal melanoma, on 2 May 2022. Primary uveal melanoma has a high risk of progressing to metastat
Externí odkaz:
https://doaj.org/article/a2b75b4d0cba47a79362359f4283b693
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm caused by a BCR-ABL fusion gene. Imatinib has significantly improved the treatment of CML as a first-generation tyrosine kinase inhibitor (TKIs). The T315I mutant form of BCR-ABL is the
Externí odkaz:
https://doaj.org/article/8cda950c119841debfe2754f39f1b3ea
Autor:
Kaijian Hou, Zhuo-Xun Wu, Xuan-Yu Chen, Jing-Quan Wang, Dongya Zhang, Chuanxing Xiao, Dan Zhu, Jagadish B. Koya, Liuya Wei, Jilin Li, Zhe-Sheng Chen
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-28 (2022)
Abstract The role of microbiota in health and diseases is being highlighted by numerous studies since its discovery. Depending on the localized regions, microbiota can be classified into gut, oral, respiratory, and skin microbiota. The microbial comm
Externí odkaz:
https://doaj.org/article/840bb506acaf4974bcf1db66dfaf1c8f
Autor:
Dan-Dan Shen, Jing-Ru Pang, Ya-Ping Bi, Long-Fei Zhao, Yin-Rui Li, Li-Juan Zhao, Ya Gao, Bo Wang, Ning Wang, Liuya Wei, Huiqin Guo, Hong-Min Liu, Yi-Chao Zheng
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-19 (2022)
Abstract Background Histone lysine-specific demethylase 1 (LSD1) expression has been shown to be significantly elevated in gastric cancer (GC) and may be associated with the proliferation and metastasis of GC. It has been reported that LSD1 repressed
Externí odkaz:
https://doaj.org/article/8e174da3639944fca2b165b40cea5f06
Autor:
Fahui Li, Congying Gao, Xueming Li, Jiangyun Wang, Yao Zhao, Yu Ke, Ying Liu, Hong-Min Liu, Zhenbo Hu, Liuya Wei, Zhe-Sheng Chen
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Acute myeloid leukemia (AML) is an aggressive form of hematological neoplasia characterized by failure of myeloid differentiation. AML is a leading cause of death from leukemia. Cytarabine chemotherapy resistance is a major source of refractory/relap
Externí odkaz:
https://doaj.org/article/e4fa6642582749a0ae97a5325020f462
Autor:
Jingfang Yao, Gentao Li, Zihui Cui, Peilei Chen, Jinhong Wang, Zhenbo Hu, Lei Zhang, Liuya Wei
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Acute leukemia (AL) is characterized by excessive proliferation and impaired differentiation of leukemic cells. AL includes acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). Previous studies have demonstrated that about 10% of AML
Externí odkaz:
https://doaj.org/article/ea47c6cb87c345a3ba91ddd2309db8f2
Autor:
Xiangyu Ma, Mengjie Zhao, Zhuo-Xun Wu, Jingfang Yao, Lei Zhang, Jinhong Wang, Zhenbo Hu, Liuya Wei, Zhe-Sheng Chen
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy characterized by reduced differentiation of myeloid cells and uncontrolled cell proliferation. AML is prone to drug resistance and has a high recurrence rate during treatment with
Externí odkaz:
https://doaj.org/article/f84fd3b16d3745239252e54e6ddcbf10
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
In discovery of novel SIRT3 inhibitors for the treatment of cancer, a series of 2-(4-acrylamidophenyl)-quinoline-4-carboxylic acid derivatives were designed and synthesized. Among the derived compounds, molecule P6 exhibited SIRT3 inhibitory selectiv
Externí odkaz:
https://doaj.org/article/8ae8b28e3bad4922870e7f700d99ee2d