Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Liuhai Zheng"'
Autor:
Jichao Sun, Dinglan Wu, Liuhai Zheng, Huifang Wang, Jihao Zhou, Guangwei Shi, Jingbo Ma, Yuke Jiang, Zhiyu Dong, Jiexuan Li, Yuan-Qiao He, Chengchao Xu, Zhijie Li, Jigang Wang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 7 (2024)
Background Chimeric antigen receptor natural killer (CAR-NK) therapy holds great promise for treating hematologic tumors, but its efficacy in solid tumors is limited owing to the lack of suitable targets and poor infiltration of engineered NK cells.
Externí odkaz:
https://doaj.org/article/0da42825ed99483b9d8be09956ef2809
Autor:
Yulai Liang, Huazao Luo, Xue Li, Shuang Liu, Arslan Habib, Baoxiu Liu, Jiansheng Huang, Jingbo Wang, Han Yi, Bo Hu, Liuhai Zheng, Jun Xie, Naishuo Zhu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundIn recent years, immunotherapy has been emerging as a promising alternative therapeutic method for cancer patients, offering potential benefits. The expression of PD-L1 by tumors can inhibit the T-cell response to the tumor and allow the tu
Externí odkaz:
https://doaj.org/article/6f0a4909d6e940cfad118271e702cf01
Autor:
Huifang Wang, Runhua Zhou, Fushan Xu, Kongjun Yang, Liuhai Zheng, Pan Zhao, Guangwei Shi, Lingyun Dai, Chengchao Xu, Le Yu, Zhijie Li, Jianhong Wang, Jigang Wang
Publikováno v:
Biomaterials Research, Vol 27, Iss 1, Pp 1-28 (2023)
Abstract Targeted protein degradation (TPD) is an emerging therapeutic strategy with the potential to modulate disease-associated proteins that have previously been considered undruggable, by employing the host destruction machinery. The exploration
Externí odkaz:
https://doaj.org/article/780a8fcf780d4e3ea5ae8dae2970abbf
Autor:
Jingbo Ma, Xiaolong Xu, Chunjin Fu, Peng Xia, Ming Tian, Liuhai Zheng, Kun Chen, Xiaolian Liu, Yilei Li, Le Yu, Qinchang Zhu, Yangyang Yu, Rongrong Fan, Haibo Jiang, Zhifen Li, Chuanbin Yang, Chengchao Xu, Ying Long, Jigang Wang, Zhijie Li
Publikováno v:
Biomaterials Research, Vol 26, Iss 1, Pp 1-20 (2022)
Abstract Background It is highly desirable to develop new therapeutic strategies for gastric cancer given the low survival rate despite improvement in the past decades. Cadherin 17 (CDH17) is a membrane protein highly expressed in cancers of digestiv
Externí odkaz:
https://doaj.org/article/e4a9c82e7d4b4fa693ffea4095a0dff6
Autor:
Xue Li, Zhenni Wang, Jiansheng Huang, Huazao Luo, Sibo Zhu, Han Yi, Liuhai Zheng, Bo Hu, Lili Yu, Lingzhi Li, Jun Xie, Naishuo Zhu
Publikováno v:
FEBS Open Bio, Vol 9, Iss 6, Pp 1063-1070 (2019)
DNA methylation of promoter regions is often associated with epigenetic silencing of gene expression, and DNA methyltransferase (DNMTs) has been used to suppress gene expression. In order to explore the synergistic roles of two methyltransferase memb
Externí odkaz:
https://doaj.org/article/307406c4329c4ae28dc5714b2026b480
Autor:
Qian Zhang, Piao Luo, Liuhai Zheng, Jiayun Chen, Junzhe Zhang, Huan Tang, Dandan Liu, Xueling He, Qiaoli Shi, Liwei Gu, Jiahao Li, Qiuyan Guo, Chuanbin Yang, Yin Kwan Wong, Fei Xia, Jigang Wang
Publikováno v:
Journal of Pharmaceutical Analysis. 12:570-582
Hepatic stellate cells (HSCs) are essential drivers of fibrogenesis. Inducing activated-HSC apoptosis is a promising strategy for treating hepatic fibrosis. 18beta-glycyrrhetinic acid (18β-GA) is a natural compound that exists widely in herbal medic
Publikováno v:
Journal of Cancer
Esophageal squamous cell carcinoma (ESCC) is one of the most common cancers worldwide. ESCC has a generally poor prognosis and there is a lack of available biomarkers for diagnosis and prognosis. The aim of the study was to identify novel biomarkers
Autor:
Yanqing Liu, Peng Gao, Qian Zhang, Yuqing Meng, Chengchao Xu, Fei Xia, Zhijie Li, Liuhai Zheng, Lingyun Dai, Jigang Wang, Jia Yun Chen, Wei Xiao, Fan Yang, Yongping Zhu, Liwei Gu, Junzhe Zhang
Background Malaria is a devastating infectious disease that disproportionally threatens hundreds of millions of people in developing countries. In the history of anti-malaria campaign, chloroquine (CQ) has played an indispensable role, however, its m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e226e9b12b471ce08165515c557b25ce
https://doi.org/10.21203/rs.3.rs-958967/v1
https://doi.org/10.21203/rs.3.rs-958967/v1
Autor:
Qian Zhang, Piao Luo, Fei Xia, Huan Tang, Jiayun Chen, Junzhe Zhang, Dandan Liu, Yongping Zhu, Yanqing Liu, Liwei Gu, Liuhai Zheng, Zhijie Li, Fan Yang, Lingyun Dai, Fulong Liao, Chengchao Xu, Jigang Wang
Publikováno v:
Cell chemical biology. 29(8)
Sepsis is a systemic inflammatory response syndrome with high mortality and morbidity worldwide. In this study, we demonstrate that capsaicin not only suppresses inflammation in lipopolysaccharide (LPS)-induced macrophages, but also effectively inhib
Autor:
Zhijie Li, Liuhai Zheng, Xin Peng, Xiaodan Su, Jingbo Ma, Jun Tao, Meng Dang, Zhaogang Teng, Kun Chen, Lianhui Wang
Publikováno v:
ACS applied materialsinterfaces. 13(43)
Artificial nanomotors are undergoing significant developments in several biomedical applications. However, current experimental strategies for producing nanomotors still have inherent drawbacks such as the requirement for expensive equipment, strict