Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Liudmila V. Spirina"'
Autor:
Liudmila V. Spirina, Alexandra V. Avgustinovich, Olga V. Bakina, Sergey G. Afanas’ev, Maxim Yu. Volkov, Sergey V. Vtorushin, Irina V. Kovaleva, Tatyana S. Klyushina, Igor O. Munkuev
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 2, Pp 1281-1290 (2024)
Heterogeneity of gastric cancer (GC) is the main trigger of the disease’s relapse. The aim of this study was to investigate the connections between targeted genes, cancer clinical features, and the effectiveness of FLOT chemotherapy. Twenty-one pat
Externí odkaz:
https://doaj.org/article/197d590cd68244808f46509e250c7bb7
Autor:
Alexandra V. Avgustinovich, Olga V. Bakina, Sergey G. Afanas’ev, Liudmila V. Spirina, Alexander M. Volkov
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 9, Pp 7642-7649 (2023)
Introduction: The landscape of gastric cancer treatment has changed owing to the widespread use of immune checkpoint inhibitors. Autophagy, involved in regulating the immune system, is a potential trigger of immunity in tumors. This study aims to fin
Externí odkaz:
https://doaj.org/article/530822d3cca042c3941748cbcf6f3ce1
Autor:
Liudmila V. Spirina, Alexandra V. Avgustinovich, Olga V. Bakina, Sergey G. Afanas’ev, Maxim Yu. Volkov, Amina Y. Kebekbayeva
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 7, Pp 2772-2782 (2022)
Autophagy plays a dual role in oncogenesis processes. On one hand, autophagy enhances the cell resistance to oncogenic factors, and on the other hand, it participates in the tumor progression. The aim of the study was to find the associations between
Externí odkaz:
https://doaj.org/article/b6c7b52318d24c41a9471f3af15e7a3d
Publikováno v:
Клиническая и экспериментальная тиреоидология, Vol 15, Iss 3, Pp 110-117 (2020)
Autophagy is an important intracellular process that supports cell death and survival. Oncogenesis is associated with a change in the AKT/mTOR signaling pathway status. At the same time, the existence of protective autophagy, as one of the mechanisms
Externí odkaz:
https://doaj.org/article/232e2c0db1af49f4890c9dedbb0af73b
Publikováno v:
Heliyon, Vol 5, Iss 8, Pp e02090- (2019)
Sex hormones, regulating normal physiological processes of most tissues and organs, are considered to be one of the key factors in the development of hormone-dependent cancer and formation of the hormone-resistant tumor phenotype. Recently, the impor
Externí odkaz:
https://doaj.org/article/aaf6d07af3854dd5a94c7eddda1c1419
Autor:
Liudmila V. Spirina, Zahar A. Yurmazov, Alexey K. Gorbunov, Evgeny A. Usynin, Nadezhda A. Lushnikova, Irina V. Kovaleva
Publikováno v:
Cells, Vol 9, Iss 7, p 1680 (2020)
Metastasis involves the spread of cancer cells from the primary tumor to surrounding tissues and distant organs and is the primary cause of cancer morbidity and mortality. The aim of the study was the determination of change in molecular factors expr
Externí odkaz:
https://doaj.org/article/fbb9270161ab4d52896d6b265cb5a975
Autor:
Liudmila V, Spirina, Nadezhda V, Masunova, Vladimir N, Masunov, Victoria V, Makova, Yumzhana S, Dagbaeva, Irina V, Kovaleva
Publikováno v:
Asian Pacific Journal of Cancer Prevention. 23:2191-2197
The widespread infectious disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) significantly impacts major human diseases. It is undoubtedly evident that cancer patients are more susceptible to the infection and at a higher
Autor:
Liudmila V. Spirina, Irina V. Kovaleva, Svetlana Yu. Chizhevskaya, Anastasiya V. Chebodaeva, Nataliya V. Tarasenko
Publikováno v:
Genes; Volume 14; Issue 3; Pages: 685
Background: Autophagy is a stress response mechanism that causes cellular components to degrade. Its defects were associated with multiple pathologies, including cancers. Thyroid cancer is known to be the most prevalent form of malignant neoplasm amo
Autor:
O. V. Cheremisina, Michail Buldakov, Evgeny Choynzonov, Sergey G Afanas'ev, A. V. Avgustinovich, Alexey Y Dobrodeev, Olga V. Bakina, Liudmila V. Spirina
Publikováno v:
Current Pharmaceutical Design. 27:2436-2444
Gastric cancer is the second most common cause of cancer-related deaths in the world. The surgical management of the tumor is the best therapeutic option for gastric cancer patients. A combination of a heterogeneous distribution of genetic and enviro
Autor:
Liudmila V. Spirina, Vladimir N. Masunov, Denis A. Dyakov, Olga E. Akbasheva, Amina Y. Kebekbayeva, Igor Yu. Shuvalov, Nadezhda V. Masunova, Irina V. Kovaleva, Yumzhana Dagbaeva
Publikováno v:
Indian journal of clinical biochemistry : IJCB.
Multiple pathogenic mechanisms are found in SARS-CoV2 systemic inflammation. Oxidative stress, altered proteolysis, hypercoagulation, and metabolic disorders are significant in virus-induced lesions. The study aimed to investigate the biochemical mec