Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Liudmila V. Efremova"'
Autor:
Larisa V. Kameneva, Marina S. Konkova, Liudmila V. Efremova, A. Yu. Alekseeva, T. D. Smirnova, Svetlana V. Kostyuk, Natalya N. Veiko
Publikováno v:
Bulletin of Experimental Biology and Medicine. 149:191-195
NO synthesis by endothelial cells plays an important role in normal function of the cardiovascular system. This work was designed to evaluate the role of variations in properties of extracellular DNA in the regulation of NO synthesis. We studied the
Autor:
Ancha Baranova, Natalya N. Veiko, Liudmila V. Efremova, Anna Yu. Alekseeva, Tatiana D. Smirnova, Aleksei V. Ermakov, K. V. Glebova, Svetlana V. Kostyuk
Publikováno v:
Mutation research. 729(1-2)
The development of the bystander effect induced by low doses of irradiation in human umbilical vein endothelial cells (HUVECs) depends on extracellular DNA (ecDNA) signaling pathway. We found that the changes in the levels of ROS and NO production by
Autor:
T. D. Smirnova, A. Yu. Alekseeva, Marina S. Konkova, Svetlana V. Kostyuk, Liudmila V. Efremova, Elizaveta S. Ershova, I. L. Konorova, N. N. Veiko
Publikováno v:
Bulletin of experimental biology and medicine. 149(2)
Fragments of extracellular DNA are permanently released into the blood flow due to cell apoptosis and possible de novo DNA synthesis. To find out whether extracellular DNA can affect the synthesis of nitric oxide (NO), one of key vascular tone regula
Autor:
Liudmila V. Efremova, Svetlana V. Kostyuk, Marina S. Konkova, Tatiana D. Smirnova, Aleksei V. Ermakov, Elena M. Malinovskaya, Natalya N. Veiko
Publikováno v:
Mutation research. 712(1-2)
The human umbilical vein endothelial cells culture was exposed to X-ray radiation in a low dose of 10 cGy. The fragments of extracellular genomic DNA (ecDNAR) were isolated from the culture medium after the short-term incubation. A culture medium of
Autor:
Anna Yu. Alekseeva, Larisa V. Kameneva, Elena M. Malinovskaya, Svetlana V. Kostyuk, T. D. Smirnova, Marina S. Konkova, Liudmila V. Efremova, Liudmila Lyubchenko, A. V. Ermakov, Natalya N. Veiko
Publikováno v:
Circulating Nucleic Acids in Plasma and Serum ISBN: 9789048193813
CpG-enriched rDNA accumulating in human cfDNA significantly stimulate gene transcription in mesenchymal stem cells by activating TLR9 and MyD88-dependent signaling pathways and inhibiting differentiation of mesenchymal stem cells into adipocytes. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90b0b01c4324c1f50495cf79d5366f92
https://doi.org/10.1007/978-90-481-9382-0_27
https://doi.org/10.1007/978-90-481-9382-0_27
Autor:
Liudmila V. Efremova, Marina S. Konkova, Liudmila Lyubchenko, A. V. Ermakov, Svetlana V. Kostyuk, T. D. Smirnova, Natalya N. Veiko
Publikováno v:
Circulating Nucleic Acids in Plasma and Serum ISBN: 9789048193813
Following exposure to X-radiation (10 cGy), human mesenchymal stem cells (MSCs) appear to exhibit transposition of 1q12 loci of the homologous chromosomes from the perimembrane regions deep into the nucleus, their approximation and activation of chro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e36a0c6163bd0eaa61dc187ddd3baa7
https://doi.org/10.1007/978-90-481-9382-0_31
https://doi.org/10.1007/978-90-481-9382-0_31
Publikováno v:
Circulating Nucleic Acids in Plasma and Serum ISBN: 9789048193813
It is known that the content of ecDNA is enriched by the CpG-motifs. Current data show that neural cells can also be affected by bacterial or viral CpG-rich DNA. Here we investigated the effect of ecDNA, namely the transcribed region of the CpG-rich
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1a25cabcf359f2c20db245e93f0197d
https://doi.org/10.1007/978-90-481-9382-0_29
https://doi.org/10.1007/978-90-481-9382-0_29
Autor:
Aleksei V. Ermakov, Liudmila V. Efremova, Natalya N. Veiko, Natalya A. Egolina, Svetlana V. Kostyuk, Marina S. Konkova
Publikováno v:
Mutation research. 669(1-2)
X-radiation (10cGy) was shown to induce in human lymphocytes transposition of homologous chromosomes loci from the membrane towards the centre of the nucleus and activation of the chromosomal nucleolus-forming regions (NFRs). These effects are transm
Influence of X-ray and/or CpG-DNA induced oxidative stress on adaptive response in human lymphocytes
Autor:
Liudmila V. Efremova, Aleksei V. Ermakov, Marina S. Konkova, Natalya N. Veiko, Svetlana V. Kostyuk
Publikováno v:
International Journal of Low Radiation. 7:446
Peripheral blood lymphocytes of apparently healthy donors were exposed to low-dose ionising radiation and/or human-genome CpG-DNA fragments accumulating in total extracellular DNA. Both factors administered separately appeared to induce transposition