Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Liubov M, Lifshits"'
Ruthenium Photosensitizers for NIR PDT Require Lowest-Lying Triplet Intraligand (3IL) Excited States
Autor:
Liubov M. Lifshits, John A. Roque III, Elamparuthi Ramasamy, Randolph P. Thummel, Colin G. Cameron, Sherri A. McFarland
Publikováno v:
Journal of Photochemistry and Photobiology, Vol 8, Iss , Pp 100067- (2021)
A family of complexes of the type [Ru(tpbn)(IP-R)(4-pic)]Cl2 (tbpn=2,2′-(4-(tert‑butyl)pyridine-2,6-diyl)bis(1,8-napthyridine); 4-pic = 4-picoline; IP-R = imidazo[4,5-f][1,10]phenanthroline attached to an aromatic group R for 2–8 and H for 1) w
Externí odkaz:
https://doaj.org/article/192598318379494c8456464426f18c1f
Autor:
Prathyusha Konda, Liubov M. Lifshits, John A. Roque, Houston D. Cole, Colin G. Cameron, Sherri A. McFarland, Shashi Gujar
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
We report a new class of ruthenium (Ru)-based photosensitizers that induce potent cytotoxicity in melanoma cells following activation with NIR light. In addition to the direct cytotoxic effect, this Ru-based photodynamic therapy induces immunogenic c
Externí odkaz:
https://doaj.org/article/cd53397beefa46e8a7d7ee5b20571408
Autor:
Rebeca T, Stiepel, Erik S, Pena, Stephen A, Ehrenzeller, Matthew D, Gallovic, Liubov M, Lifshits, Christopher J, Genito, Eric M, Bachelder, Kristy M, Ainslie
Publikováno v:
Journal of Controlled Release. 351:883-895
Effective drug delivery requires ample dosing at the target tissue while minimizing negative side effects. Drug delivery vehicles such as polymeric nanoparticles (NPs) are often employed to accomplish this challenge. In this work, drug release of num
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c83059266f159c8131826791a0864d1
https://doi.org/10.1016/j.jconrel.2022.09.067
https://doi.org/10.1016/j.jconrel.2022.09.067
Autor:
Meital Eckshtain-Levi, Cole J. Batty, Liubov M. Lifshits, Brandon McCammitt, Kathryn M. Moore, Eva A. Amouzougan, Rebeca T. Stiepel, Eliza Duggan, Ted M. Ross, Eric M. Bachelder, Kristy M. Ainslie
Publikováno v:
ACS Appl Mater Interfaces
A zinc-carnosine (ZnCar) metal-organic coordination polymer was fabricated in biologically relevant HEPES buffer for use as a vaccine platform. In vitro, ZnCar exhibited significantly less cytotoxicity than a well-established zeolitic imidazolate fra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e300856dcb90f6c626428b07250e1369
https://pubmed.ncbi.nlm.nih.gov/35704854
https://pubmed.ncbi.nlm.nih.gov/35704854
Autor:
Cole J. Batty, Liubov M. Lifshits, Dylan A. Hendy, Meital Eckshtain-Levi, Luis A. Ontiveros-Padilla, Michael A. Carlock, Ted M. Ross, Eric M. Bachelder, Kristy M. Ainslie
Publikováno v:
The AAPS Journal. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::192583b8437990cb26acf0475bdc2f5f
https://doi.org/10.1208/s12248-023-00786-6
https://doi.org/10.1208/s12248-023-00786-6
Autor:
Erik S. Pena, Liubov M. Lifshits, Meital Eckshtain‐Levi, Eric M. Bachelder, Kristy M. Ainslie
Publikováno v:
WIREs Nanomedicine and Nanobiotechnology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6a1c84157dc40d840f5db5be557a834
https://doi.org/10.1002/wnan.1877
https://doi.org/10.1002/wnan.1877
Autor:
John A. Roque III, Houston D. Cole, Patrick C. Barrett, Liubov M. Lifshits, Rachel O. Hodges, Susy Kim, Gagan Deep, Antonio Francés-Monerris, Marta E. Alberto, Colin G. Cameron, Sherri A. McFarland
Publikováno v:
J Am Chem Soc
Ru(II) complexes that undergo photosubstitution reactions from triplet metal-centered ((3)MC) excited states are of interest in photochemotherapy (PCT) for their potential to produce cytotoxic effects in hypoxia. Dual-action systems that incorporate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5bcf1369730a24b31c2d26c96d9a31
https://europepmc.org/articles/PMC9098688/
https://europepmc.org/articles/PMC9098688/
Autor:
Colin G. Cameron, Liubov M. Lifshits, Sherri A. McFarland, John Roque, Houston D. Cole, Randolph P. Thummel
Publikováno v:
Chembiochem
The design of near-infrared (NIR)-active photosensitizers (PSs) for light-based cancer treatments such as photodynamic therapy (PDT) has been a challenge. While several NIR-Ru(II) scaffolds have been reported, this approach has not been proven in cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74d61bf99ab3d4597b8123d3cfe75815
https://doi.org/10.1002/cbic.202000419
https://doi.org/10.1002/cbic.202000419
Autor:
Sherri A. McFarland, S.D. Kim, Houston D. Cole, Susan Monro, Randolph P. Thummel, Prathyusha Konda, Colin G. Cameron, Shashi Gujar, Gagan Deep, John Roque, Liubov M. Lifshits, David von Dohlen
Publikováno v:
Chemical Science
Mounting evidence over the past 20 years suggests that photodynamic therapy (PDT), an anticancer modality known mostly as a local treatment, has the capacity to invoke a systemic antitumor immune response, leading to protection against tumor recurren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28134ca36bb4489c5ba2d3e3a8a0329c
https://doi.org/10.1039/d0sc03875j
https://doi.org/10.1039/d0sc03875j
Autor:
Gagan Deep, John Roque, S.D. Kim, Susan Monro, Colin G. Cameron, Marta E. Alberto, David von Dohlen, Liubov M. Lifshits, Nino Russo, Ge Shi, Houston D. Cole, Sherri A. McFarland, Patrick C. Barrett
Publikováno v:
Chemical Science. 11:9784-9806
Hypoxia presents a two-fold challenge in the treatment of cancer, as low oxygen conditions induce biological changes that make malignant tissues simultaneously more aggressive and less susceptible to standard chemotherapy. This paper reports the firs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17c139a17049d56831c024f85a72a5e1
https://doi.org/10.1039/d0sc03008b
https://doi.org/10.1039/d0sc03008b