Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Liubing Du"'
Autor:
Yiling Jiang, Kuijie Tong, Roubin Yao, Yuanze Zhou, Hanwen Lin, Liubing Du, Yunyun Jin, Liu Cao, Jingquan Tan, Xing-Ding Zhang, Deyin Guo, Ji-An Pan, Xiaoxue Peng
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Background Analysis of viral protein–protein interactions is an essential step to uncover the viral protein functions and the molecular mechanism for the assembly of a viral protein complex. We employed a mammalian two-hybrid system to scr
Externí odkaz:
https://doaj.org/article/d36d9175509b40f382a7d03d009844a8
Autor:
Liubing Du, Yanchun Xie, Kai Zheng, Niu Wang, Mingcheng Gao, Ting Yu, Liu Cao, QianQian Shao, Yong Zou, Wei Xia, Qianglin Fang, Bo Zhao, Deyin Guo, Xiaoxue Peng, Ji-An Pan
Publikováno v:
Redox Biology, Vol 48, Iss , Pp 102199- (2021)
3CLpro is a key proteinase for SARS-CoV-2 replication and serves as an important target for antiviral drug development. However, how its activity is regulated intracellularly is still obscure. In this study, we developed a 3CLpro protease activity re
Externí odkaz:
https://doaj.org/article/96766fb4cd0a4d358322855d4479906c
Autor:
Zhennan Zhao, Zong-Wan Mao, Lu Zhang, Yuebin Zhang, Ruyan Liao, Yanxuan Xie, Guohui Li, Kai Lu, Xuan Tao, Liubing Du, Jun Dai, Pei-Hui Wang, Ji-An Pan, Wei Xia, Huiling Cai
Publikováno v:
Chemical Science
The SARS-CoV-2 3-chymotrypsin-like protease (3CLpro or Mpro) is a key cysteine protease for viral replication and transcription, making it an attractive target for antiviral therapies to combat the COVID-19 disease. Here, we demonstrate that bismuth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f91cd99cd1b359ed97fe297a321f33cb
http://europepmc.org/articles/PMC8565384
http://europepmc.org/articles/PMC8565384
Autor:
Ting Yu, Qiao Ling, Mengxin Xu, Niu Wang, Lixia Wang, Hanwen Lin, Manqi Cao, Yong Ma, Yuanyuan Wang, Kuibiao Li, Liubing Du, Yunyun Jin, Ying Li, Deyin Guo, Xiaoxue Peng, Yao‐qing Chen, Bo Zhao, Ji‐An Pan
Publikováno v:
Journal of Medical Virology. 94
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57a57c5c962b10ec56a9aa31b16ddf5e
https://doi.org/10.1002/jmv.27987
https://doi.org/10.1002/jmv.27987
Autor:
Liu Cao, Deyin Guo, Yanxi Ji, Wei-Chen Wu, Yun-Yun Jin, Liubing Du, Yanchun Xie, Jiang Yiling, Ji-An Pan, Fan Xing, Xiaoxue Peng, Fuxiang Zheng, Hanwen Lin, Mang Shi, Kuijie Tong
Publikováno v:
Virologica Sinica
SARS-CoV-2 causes the pandemic of COVID-19 and no effective drugs for this disease are available thus far. Due to the high infectivity and pathogenicity of this virus, all studies on the live virus are strictly confined in the biosafety level 3 (BSL3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dbe6a6822706b054a0c14370729061a
http://europepmc.org/articles/PMC8127439
http://europepmc.org/articles/PMC8127439
Autor:
Ting Yu, Qiao Ling, Mengxin Xu, Niu Wang, Lixia Wang, Hanwen Lin, Manqi Cao, Yong Ma, Yuanyuan Wang, Kuibiao Li, Liubing Du, Yunyun Jin, Ying Li, Deyin Guo, Xiaoxue Peng, Yao‐qing Chen, Bo Zhao, Ji‐An Pan
Publikováno v:
Journal of medical virology. 94(9)
As one of the most rapidly evolving proteins of the genus Betacoronavirus, open reading frames (ORF8's) function and potential pathological consequence in vivo are still obscure. In this study, we show that the secretion of ORF8 is dependent on its N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8fdf0538edce11ec6c9e689632a6866
https://pubmed.ncbi.nlm.nih.gov/35570330
https://pubmed.ncbi.nlm.nih.gov/35570330
Autor:
Xuan Tao, Lu Zhang, Liubing Du, Kai Lu, Zhennan Zhao, Yanxuan Xie, Xiaobo Li, Shuxiang Huang, Pei-Hui Wang, Ji-An Pan, Wei Xia, Jun Dai, Zong-Wan Mao
Publikováno v:
Journal of inorganic biochemistry. 231
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic is currently the major challenge to global public health. Two proteases, papain-like protease (PLpro) and the 3-chymotrypsin-like protease (3CLpro or Mpro), are indispensable f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d328e8b6f8b9a6e0fdcdcf026da152c
https://pubmed.ncbi.nlm.nih.gov/35255411
https://pubmed.ncbi.nlm.nih.gov/35255411
Autor:
Mingcheng Gao, Yong Zou, Ji-An Pan, Wei Xia, Bo Zhao, Liu Cao, Kai Zheng, QianQian Shao, Xiaoxue Peng, Yanchun Xie, Qianglin Fang, Liubing Du, Deyin Guo, Niu Wang, Ting Yu
Publikováno v:
Redox Biology
Redox Biology, Vol 48, Iss, Pp 102199-(2021)
Redox Biology, Vol 48, Iss, Pp 102199-(2021)
3CLpro is a key proteinase for SARS-CoV-2 replication and serves as an important target for antiviral drug development. However, how its activity is regulated intracellularly is still obscure. In this study, we developed a 3CLpro protease activity re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ded845a18946938bfb7a977049eefa0e
http://europepmc.org/articles/PMC8616692
http://europepmc.org/articles/PMC8616692