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Akademický článek
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Publikováno v:
bchm. 388:427-435
Human kallikrein-related peptidase 12 (KLK12) is a new member of the human tissue kallikrein family. Preliminary studies suggest that KLK12 is differentially expressed in breast cancer and may have potential use as a cancer biomarker. It has been pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c0061f45072238d651497b6de0c6b0
https://doi.org/10.1515/bc.2007.049
https://doi.org/10.1515/bc.2007.049
Autor:
Manik C. Ghosh, Iacovos P. Michael, Dionyssios Katsaros, Antoninus Soosaipillai, Eleftherios P. Diamandis, Liu-Ying Luo, Carla A. Borgoño, Linda Grass, Julie L.V. Shaw
Publikováno v:
Journal of Biological Chemistry. 282:2405-2422
Human tissue kallikrein 14 (KLK14) is a novel extracellular serine protease. Clinical data link KLK14 expression to several diseases, primarily cancer; however, little is known of its (patho)-physiological role. To functionally characterize KLK14, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5b91ee7639abd9ea4bea4847e6d67d2
https://doi.org/10.1074/jbc.m608348200
https://doi.org/10.1074/jbc.m608348200
Publikováno v:
Clinica Chimica Acta. 337:115-126
Background: The human kallikrein 10 (KLK10) gene is a new member of the human tissue kallikrein gene family. It encodes for a secreted serine protease (hK10) with predicted trypsin-like enzymatic activity. KLK10 is highly expressed in the sex organs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aabf11e046f93b8da707b3fb046f728
https://doi.org/10.1016/j.cccn.2003.07.008
https://doi.org/10.1016/j.cccn.2003.07.008
Autor:
Eleftherios P. Diamandis, Panagiotis A. Papanastasiou, Constantina Petraki, Vassiliki Karavana, Alkiviadis Gregorakis, Liu-Ying Luo
Publikováno v:
Prostate Cancer and Prostatic Diseases. 6:223-227
Human kallikreins 6, 10 and 13 (hK6, hK10 and hK13) are expressed by many normal, mainly glandular tissues, including prostatic epithelium. Some kallikreins may function as tumor suppressors or are downregulated during cancer progression. The aim of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::913e031461f08c8acf7614bbe6c207fe
https://doi.org/10.1038/sj.pcan.4500674
https://doi.org/10.1038/sj.pcan.4500674
Publikováno v:
Journal of Histochemistry & Cytochemistry. 50:1247-1261
The normal epithelial cell-specific 1 (NES1) gene (official name kallikrein gene 10, KLK10) was recently cloned and encodes for a putative secreted serine protease (human kallikrein 10, hK10). Several studies have confirmed that hK10 shares many simi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf77829a9e79929561f42c749272c78
https://doi.org/10.1177/002215540205000912
https://doi.org/10.1177/002215540205000912
Autor:
Kyriakos Revelos, Vasso N. Karavana, Liu-Ying Luo, Eleftherios P. Diamandis, Constantina Petraki
Publikováno v:
The Histochemical Journal. 34:313-322
Tissue kallikreins are thought to be present in the pancreatic islets of Langerhans and to aid in the conversion of proinsulin to insulin. In recent immunohistochemical studies, we observed strong staining of the newly identified human kallikreins 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94e3910d118ff1436e6b3c9ed6f5b569
https://doi.org/10.1023/a:1023394030036
https://doi.org/10.1023/a:1023394030036
Autor:
Eleftherios P. Diamandis, Antoninus Soosaipillai, Liu-Ying Luo, John A. Foekens, Maxime P. Look
Publikováno v:
British Journal of Cancer
British Journal of Cancer, 86, 1790-1796. Nature Publishing Group
British Journal of Cancer, 86, 1790-1796. Nature Publishing Group
The human tissue kallikreins are secreted serine proteases, encoded by a group of homologous genes clustered in tandem on chromosome 19q13.3-4. Human kallikrein 6 and human kallikrein 10 are two new members of this family. Recently, we developed high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36c7ca478c7ac21a5c6c6e37561957a5
https://doi.org/10.1038/sj.bjc.6600323
https://doi.org/10.1038/sj.bjc.6600323
Publikováno v:
Clinical Chemistry. 47:237-246
Background: The human kallikrein 10 gene [KLK10, also known as normal epithelial cell-specific 1 gene (NES1)] is a member of the human kallikrein gene family. The KLK10 gene encodes for a secreted serine protease (hK10). We hypothesize that hK10 is s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f689f86cc6603ffe9cf48deec01f9d4
https://doi.org/10.1093/clinchem/47.2.237
https://doi.org/10.1093/clinchem/47.2.237