Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Liu-Qiong Meng"'
Autor:
Shu-Ping Wang, Shi-Qi Wu, Shi-Hui Huang, Yi-Xuan Tang, Liu-Qiong Meng, Feng Liu, Qi-Hua Zhu, Yun-Gen Xu
Publikováno v:
Cell Death and Disease, Vol 12, Iss 12, Pp 1-12 (2021)
Abstract Inducing homologous-recombination (HR) deficiency is an effective strategy to broaden the indications of PARP inhibitors in the treatment of triple-negative breast cancer (TNBC). Herein, we find that repression of the oncogenic transcription
Externí odkaz:
https://doaj.org/article/9baa2cb5f0c04c9c85888533a9fe3b3c
Discovery of Potent and Novel Dual PARP/BRD4 Inhibitors for Efficient Treatment of Pancreatic Cancer
Autor:
Lei Huang, Qian-Wen Lin, Shuping Wang, Qihua Zhu, Qin Sun, Yungen Xu, Shi-Qi Wu, Shi-Hui Huang, Ling-Li Gao, Liu-Qiong Meng, Yi Zou, Yu Li
Publikováno v:
Journal of Medicinal Chemistry. 64:17413-17435
Targeting poly(ADP-ribose) polymerase1/2 (PARP1/2) is a promising strategy for the treatment of pancreatic cancer with breast cancer susceptibility gene (BRCA) mutation. Inducing the deficiency of homologous recombination (HR) repair is an effective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d22c5fe6579643fc94e1bcf16d3612
https://doi.org/10.1021/acs.jmedchem.1c01535
https://doi.org/10.1021/acs.jmedchem.1c01535