Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Liu Dou"'
Autor:
Francesca K.H. Gavins, Liu Dou, Yujia Qin, Christine M. Madla, Sudaxshina Murdan, Abdul W. Basit, Yang Mai, Mine Orlu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 160, Iss , Pp 114329- (2023)
P-glycoprotein (P-gp), breast cancer resistance protein (BCRP), and multidrug resistance-associated protein 2 (MRP2) are clinically relevant efflux transporters implicated in the oral absorption of many food and drug substrates. Here, we hypothesised
Externí odkaz:
https://doaj.org/article/7164c35731e2421c9dfdd9383d1c9516
Autor:
Liu, Dou, Han, Ying, Wang, Xiandi, Tan, Xiaomei, Liu, Di, Qian, Guangwu, Li, Kang, Pu, Dan, Yin, Rong
The integration of Artificial Intelligence (AI) in healthcare presents a transformative potential for enhancing operational efficiency and health outcomes. Large Language Models (LLMs), such as ChatGPT, have shown their capabilities in supporting med
Externí odkaz:
http://arxiv.org/abs/2405.00728
Autor:
Vipul Yadav, Aileen House, Silvia Matiz, Laura E. McCoubrey, Kimberly A. Bettano, Leena Bhave, Meiyao Wang, Peter Fan, Siqun Zhou, Janice D. Woodhouse, Eirini Poimenidou, Liu Dou, Abdul W. Basit, Lily Y. Moy, Robert Saklatvala, Laxminarayan G. Hegde, Hongshi Yu
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2385 (2022)
Janus kinase (JAK) inhibitors, such as tofacitinib (Xeljanz) and filgotinib (Jyseleca), have been approved for treatment of ulcerative colitis with several other JAK inhibitors in late-stage clinical trials for inflammatory bowel disease (IBD). Despi
Externí odkaz:
https://doaj.org/article/f846cb0cf29a4fa0a0c6b7c02c1e2aed
Autor:
Christine M. Madla, Yujia Qin, Francesca K. H. Gavins, Jing Liu, Liu Dou, Mine Orlu, Sudaxshina Murdan, Yang Mai, Abdul W. Basit
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 1030 (2022)
Wistar and Sprague Dawley are the most common strains of rat used in pharmaceutical research and are used interchangeably in pre-clinical drug development. No studies have assessed whether Wistar and Sprague Dawley rats are equivalent in the gastroin
Externí odkaz:
https://doaj.org/article/3c08407bfa74441cb5d7c0250cc17c72
Autor:
Yang Mai, Francesca K. H. Gavins, Liu Dou, Jing Liu, Farhan Taherali, Manal E. Alkahtani, Sudaxshina Murdan, Abdul W. Basit, Mine Orlu
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1789 (2021)
Intestinal interactions with nutrients, xenobiotics and endogenous hormones can influence the expression of clinically relevant membrane transporters. These changes in the gastrointestinal (GI) physiology can in turn affect the absorption of numerous
Externí odkaz:
https://doaj.org/article/2d4b3a316dbd4ec8bb83d4f3f3d1c4d8
Autor:
Liu Dou, Francesca K. H. Gavins, Yang Mai, Christine M. Madla, Farhan Taherali, Mine Orlu, Sudaxshina Murdan, Abdul W. Basit
Publikováno v:
Pharmaceutics, Vol 12, Iss 4, p 296 (2020)
The rat is one of the most commonly used animal models in pre-clinical studies. Limited information between the sexes and the effect of food consumption on the gastrointestinal (GI) physiology, however, is acknowledged or understood. This study aimed
Externí odkaz:
https://doaj.org/article/8d42124ecf9d4133af246dbee13d7158
Publikováno v:
Pharmaceutics, Vol 11, Iss 5, p 228 (2019)
It is known that males and females respond differently to medicines and that differences in drug behaviour are due to inter-individual variability and sex specificity. In this work, we have examined the influence of pharmaceutical excipients on drug
Externí odkaz:
https://doaj.org/article/0b6ac5163e41473d890bfafcdf6516fe
Publikováno v:
In Science of the Total Environment 1 October 2024 945
Publikováno v:
In Journal of Food Composition and Analysis May 2024 129
Publikováno v:
In Applied Geochemistry September 2023 156