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Akademický článek

Genotype-phenotype Correlations of Ocular Posterior Segment Abnormalities in Marfan Syndrome

Autor: Yan Liu, BM, Yuqiao Ju, MM, Tian-hui Chen, MM, Yong-xiang Jiang, MD, PhD

Publikováno v: Ophthalmology Science, Vol 4, Iss 5, Pp 100526- (2024)

Purpose: Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in the fibrillin-1 ( (FBN1). In addition to typical phenotypes such as ectopia lentis (EL) and aortic dilation, patients with MFS are prone to ocular posterior segment

Externí odkaz: https://doaj.org/article/b055ee217b5c41ae9e9837d2ef554091

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Akademický článek

Role of Angiopoietin/Tie2 System in Sepsis: A Potential Therapeutic Target

Autor: Yawen Chi MM, Sihan Yu MM, Jia Yin BM, Danyan Liu BM, Mengke Zhuo BM, Xu Li PhD

Publikováno v: Clinical and Applied Thrombosis/Hemostasis, Vol 30 (2024)

Sepsis is a disorder of host response caused by severe infection that can lead to life-threatening organ dysfunction. There is no specific treatment for sepsis. Although there are many different pathogens that can cause sepsis, endothelial dysfunctio

Externí odkaz: https://doaj.org/article/d1fa1dec89ea4d3ca1cd87fcaca2b108

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Akademický článek

Treating Hand High-voltage Electrical Burn by Combination of Radial Artery Perforator Flap, Artificial Dermis, and Vacuum Sealing Drainage

Autor: Yibin Guo, MD, Xiaofei Liu, BM, Liping Chen, MD

Publikováno v: Plastic and Reconstructive Surgery, Global Open, Vol 11, Iss 11, p e5397 (2023)

Summary:. Severe high-voltage electrical burns (HVEBs) to the hand can result in significant injuries, requiring early use of skin flaps or grafts for reconstruction to optimize hand function recovery. However, there is currently a lack of consensus

Externí odkaz: https://doaj.org/article/79134618b0374e80b0177c9f1e64c60a

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Akademický článek

Long Non-Coding RNA LOC648987 Promotes Proliferation and Metastasis of Renal Cell Carcinoma by Regulating Epithelial-Mesenchymal Transition

Autor: Yaowu Su MM, Liang Zhou BM, Qin Yu MM, Jianjun Lu BM, Wei Liu BM

Publikováno v: Technology in Cancer Research & Treatment, Vol 20 (2021)

Renal cell carcinoma (RCC) is a type of urinary tumor with a high incidence and is often associated with tumor metastasis. Long non-coding RNA (lncRNA) regulates tumorigenesis, progression, and metastasis. However, the role and the predictive value o

Externí odkaz: https://doaj.org/article/e5226ddfaaea4c1ca338d99d723b5c1b

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Akademický článek

Long Noncoding RNA FGD5-AS1 Knockdown Decrease Viability, Migration, and Invasion of Non-Small Cell Lung Cancer (NSCLC) Cells by Regulating the MicroRNA-944/MACC1 Axis

Autor: Jian Lv MM, Qinyong Li MM, Ruiqiang Ma MM, Zhen Wang BM, Yingyu Yu MM, Huan Liu BM, Yuanxiu Miao BM, Shujuan Jiang MD

Publikováno v: Technology in Cancer Research & Treatment, Vol 20 (2021)

Objective: Long noncoding RNA FGD5 antisense RNA 1 (FGD5-AS1) participates in the regulation of non-small cell lung cancer (NSCLC) progression, but the underlying mechanisms are not fully revealed. This study aimed to determine the regulatory mechani

Externí odkaz: https://doaj.org/article/ead50a2d2da64a16b57e6580f1c34d39

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Akademický článek

CTNNB1 Knockdown Inhibits Cell Proliferation and Aldosterone Secretion Through Inhibiting Wnt/β-Catenin Signaling in H295R Cells

Autor: Tingting Zhou MM, Pengwei Luo MM, Liang Wang MD, Shiwei Yang MM, Shiyuan Qin MM, Zhitao Wei MD, Jiwen Liu BM

Publikováno v: Technology in Cancer Research & Treatment, Vol 19 (2020)

Aldosterone-producing adenomas (APA) is one of the causative factors of primary aldosteronism. Previous studies have suggested that there are somatic CTNNB1 mutations in APA, but the specific mechanism of CTNNB1 mutation in APA tumorigenesis and aldo

Externí odkaz: https://doaj.org/article/4a13411f4a25421b9c79dc53a880e500

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Akademický článek

An 8 miRNA-Based Risk Score System for Predicting the Prognosis of Patients With Papillary Thyroid Cancer

Autor: Wanwan Yi MM, Jin Liu BM, Shuping Qu MM, Hengwei Fan MM, Zhongwei Lv MD

Publikováno v: Technology in Cancer Research & Treatment, Vol 19 (2020)

Background: Dysregulation of microRNAs (miRNAs) in papillary thyroid cancer (PTC) might influence prognosis of PTC. This study is aimed to develop a risk score system for predicting prognosis of PTC. Methods: The miRNA and gene expression profiles of

Externí odkaz: https://doaj.org/article/b36e9379848d4dfbb53b0803d45b8ecd

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Akademický článek

An Integrated Study on the Antitumor Effect and Mechanism of Triphala Against Gynecological Cancers Based on Network Pharmacological Prediction and In Vitro Experimental Validation

Autor: Yuhang Zhao MM, Min Wang PhD, Jokyab Tsering MD, Hanluo Li MM, Simin Li MM, Yuepeng Li MM, Yinghua Liu BM, Xianda Hu PhD

Publikováno v: Integrative Cancer Therapies, Vol 17 (2018)

Objectives. Triphala is a herbal medicine that has been widely used for treating a variety of ailments. This study aims to systematically analyze the antitumor effects of Triphala on gynecological cancers. Methods. The antineoplastic activities of Tr

Externí odkaz: https://doaj.org/article/337df4b3f1ed46da9a2e6b7cda4b32d6

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Lack of an association between the XRCC1 Arg399Gln polymorphism and gastric cancer based on a meta-analysis

Autor: Liu Bm, You Bs, You Hy, Jun Yang, Liu Tm, Le-Qun Li, He Yc

Publikováno v: Genetics and Molecular Research. 11:3852-3860

Association between the XRCC1 Arg399Gln polymorphism and susceptibility to gastric cancer has been investigated; overall, the results have been inconclusive. We made a meta-analysis of 13 case-control studies, including 3278 cases and 6243 controls.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::928aae785181f8e22271764f1965012d
https://doi.org/10.4238/2012.november.12.2

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