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Short- and long-term effects of oral vancomycin on the human intestinal microbiota

Autor: Isaac S, Scher JU, Djukovic A, Jiménez N, Littman DR, Abramson SB, Pamer EG, Ubeda C

Publikováno v: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
r-FISABIO. Repositorio Institucional de Producción Científica
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r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)

Background: Oral vancomycin remains the mainstay of therapy for severe infections produced by Clostridium difficile, the most prevalent cause of healthcare-associated infectious diarrhoea in developed countries. However, its short-and long-term effec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::93f05506f375e855c4ef95ee7e175236
https://fundanet.fisabio.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=1427

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Decreased Bacterial Diversity Characterizes the Altered Gut Microbiota in Patients With Psoriatic Arthritis, Resembling Dysbiosis in Inflammatory Bowel Disease

Autor: Scher JU, Ubeda C, Artacho A, Attur M, Isaac S, Reddy SM, Marmon S, Neimann A, Brusca S, Patel T, Manasson J, Pamer EG, Littman DR, Abramson SB

Publikováno v: ARTHRITIS & RHEUMATOLOGY
r-FISABIO. Repositorio Institucional de Producción Científica
instname
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)

Objective. To characterize the diversity and taxonomic relative abundance of the gut microbiota in patients with never-treated, recent-onset psoriatic arthritis (PsA). Methods. High-throughput 16S ribosomal RNA pyrosequencing was utilized to compare

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b4ad1bd8b93c03762932cce60aaff921
https://fundanet.fisabio.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=8579

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Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis

Autor: Scher, JU, Sczesnak, A, Longman, RS, Segata, N, Ubeda, C, Bielski, C, Rostron, T, Cerundolo, V, Pamer, EG, Abramson, SB, Huttenhower, C, Littman, DR

Publikováno v: eLife. 2013(2)

Rheumatoid arthritis (RA) is a prevalent systemic autoimmune disease, caused by a combination of genetic and environmental factors. Animal models suggest a role for intestinal bacteria in supporting the systemic immune response required for joint inf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1064::ddf87d6d1d9ae6817032c9cb4fb6c605
http://ora.ox.ac.uk/objects/uuid:c63a0a59-1008-435d-8fdf-e5a23aeee579

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Itk negatively regulates induction of T cell proliferation by CD28 costimulation

Autor: Liao, XC, Fournier, S, Killeen, N, Weiss, A, Allison, JP, Littman, DR

Publikováno v: The Journal of experimental medicine, vol 186, iss 2

CD28 is a cell surface molecule that mediates a costimulatory signal crucial for T cell proliferation and lymphokine production. The signal transduction mechanisms of CD28 are not well understood. Itk, a nonreceptor protein tyrosine kinase specifical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::3281dd14cd3010a8855afd31a9b56392
https://escholarship.org/uc/item/2372996n

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