Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Littlefield, Ethel S."'
Autor:
Masayuki Takahashi, Benjamin K. Ayida, Dionisios Vourloumis, Qiang Zhao, Qing Han, Sofia Barluenga, Thomas Hermann, Littlefield Ethel S, Geoffrey C. Winters, Sarah Shandrick, Klaus B. Simonsen
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 14:713-718
RNA recognition by natural aminoglycoside antibiotics depends on the 2-deoxystreptamine (2-DOS) scaffold which participates in specific hydrogen bonds with the ribosomal decoding-site target. Three-dimensional structure information has been used for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1f52b134c514cbc22b59d5d02982283
https://doi.org/10.1016/j.bmcl.2003.11.028
https://doi.org/10.1016/j.bmcl.2003.11.028
Autor:
Babine Robert E, Edward L. Brown, David A. Matthews, Susan L. Binford, Stephen T. Worland, Shella A. Fuhrman, Amy K. Patick, James E. V. Harr, Reich Siegfried Heinz, Joseph T. Marakovits, Thomas J. Prins, Caroline A. Lee, Wallace Michael B, Peter S. Dragovich, Littlefield Ethel S, and Dorothy M. DeLisle, James W. Meador, Rose Ann Ferre, Clifford E. Ford, Ru Zhou, Stephen E. Webber, Jayashree Tikhe
Publikováno v:
Journal of Medicinal Chemistry. 41:2819-2834
The structure-based design, chemical synthesis, and biological evaluation of various peptide-derived human rhinovirus (HRV) 3C protease (3CP) inhibitors are described. These compounds are comprised of an ethyl propenoate Michael acceptor moiety and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ae4560588b9aa6544425b6ac69eedc
https://doi.org/10.1021/jm9800696
https://doi.org/10.1021/jm9800696
Autor:
Susumo Katoh, J. Ernest Villafranca, Cristina T. Lewis, Michael Imbacuan, Richard E. Showalter, Babine Robert E, Littlefield Ethel S, Judy V. French, Hans E. Parge, Ted M. Bleckman, John H. Tatlock, L. A. K. Pelletier
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:385-390
The design, synthesis, and structure activity relationships of a series of novel macrocyclic FKBP-12 ligands 1 are reported. The crystal structure of the complex between 7 and human FKBP-12 is reported and some SAR results are discussed based on this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d40c1f82d7ab92eaa7836f31e40e88c9
https://doi.org/10.1016/0960-894x(96)00032-7
https://doi.org/10.1016/0960-894x(96)00032-7
Autor:
S. Katoh, M. Imbacuan, John H. Tatlock, Littlefield Ethel S, R. E. Showalter, Babine Robert E, Hans E. Parge, C. T. Lewis, Jesus Ernesto Villafranca, T. M. Bleckman, J. V. French, L. A. K. Pelletier
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ddb3aaa3478b7f9137307134152fcef
https://doi.org/10.1002/chin.199625159
https://doi.org/10.1002/chin.199625159
Autor:
Barluenga, Sofia, Simonsen, Klaus B., Littlefield, Ethel S., Ayida, Benjamin K., Vourloumis, Dionisios, Winters, Geoffrey C., Takahashi, Masayuki, Shandrick, Sarah, Zhao, Qiang, Han, Qing, Hermann, Thomas
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 2004 14(3):713-718
Autor:
Babine, Robert E., Bleckman, T.M., Littlefield, Ethel S., Parge, Hans E., Pelletier, L.A.K., Lewis, Cristina T., French, Judy V., Imbacuan, Michael, Katoh, Susumo, Tatlock, John H., Showalter, Richard E., Villafranca, J.Ernest
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 1996 6(4):385-390
Publikováno v:
In Progress in Neuropsychopharmacology & Biological Psychiatry 1995 19(1):135-149