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SCPAT-GAN: Structural Constrained and Pathology Aware Convolutional Transformer-GAN for Virtual Histology Staining of Human Coronary OCT images

Autor: Li, Xueshen, Liu, Hongshan, Song, Xiaoyu, Brott, Brigitta C., Litovsky, Silvio H., Gan, Yu

There is a significant need for the generation of virtual histological information from coronary optical coherence tomography (OCT) images to better guide the treatment of coronary artery disease. However, existing methods either require a large pixe

Externí odkaz: http://arxiv.org/abs/2307.12138

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Akademický článek

Exercise mitigates reductive stress-induced cardiac remodeling in mice

Autor: Arun Jyothidasan, Sini Sunny, Asokan Devarajan, Aniqa Sayed, John Kofi Afortude, Brian Dalley, Vivek Nanda, Steven Pogwizd, Silvio H. Litovsky, Joel D. Trinity, Matthew Might, Namakkal S. Rajasekaran

Publikováno v: Redox Biology, Vol 75, Iss , Pp 103263- (2024)

The endoplasmic reticulum (ER) regulates protein folding and maintains proteostasis in cells. We observed that the ER transcriptome is impaired during chronic reductive stress (RS) in cardiomyocytes. Here, we hypothesized that a prolonged moderate tr

Externí odkaz: https://doaj.org/article/89d8b21237c04432b90821ae7822b5b0

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Structural constrained virtual histology staining for human coronary imaging using deep learning

Autor: Li, Xueshen, Liu, Hongshan, Song, Xiaoyu, Brott, Brigitta C., Litovsky, Silvio H., Gan, Yu

Histopathological analysis is crucial in artery characterization for coronary artery disease (CAD). However, histology requires an invasive and time-consuming process. In this paper, we propose to generate virtual histology staining using Optical Coh

Externí odkaz: http://arxiv.org/abs/2211.06737

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Towards reliable calcification detection: calibration of uncertainty in coronary optical coherence tomography images

Autor: Liu, Hongshan, Li, Xueshen, Bamba, Abdul Latif, Song, Xiaoyu, Brott, Brigitta C., Litovsky, Silvio H., Gan, Yu

Optical coherence tomography (OCT) has become increasingly essential in assisting the treatment of coronary artery disease (CAD). Image-guided solutions such as Percutaneous Coronary Intervention (PCI) are extensively used during the treatment of CAD

Externí odkaz: http://arxiv.org/abs/2211.06728

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Multi-scale reconstruction of undersampled spectral-spatial OCT data for coronary imaging using deep learning

Autor: Li, Xueshen, Cao, Shengting, Liu, Hongshan, Yao, Xinwen, Brott, Brigitta C., Litovsky, Silvio H., Song, Xiaoyu, Ling, Yuye, Gan, Yu

Coronary artery disease (CAD) is a cardiovascular condition with high morbidity and mortality. Intravascular optical coherence tomography (IVOCT) has been considered as an optimal imagining system for the diagnosis and treatment of CAD. Constrained b

Externí odkaz: http://arxiv.org/abs/2204.11769

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Akademický článek

The interplay between sex, time of day, fasting status, and their impact on cardiac mitochondrial structure, function, and dynamics

Autor: Mariame S. Kane, Gloria A. Benavides, Edie Osuma, Michelle S. Johnson, Helen E. Collins, Yecheng He, David Westbrook, Silvio H. Litovsky, Kasturi Mitra, John C. Chatham, Victor Darley-Usmar, Martin E. Young, Jianhua Zhang

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-20 (2023)

Abstract Mitochondria morphology and function, and their quality control by mitophagy, are essential for heart function. We investigated whether these are influenced by time of the day (TOD), sex, and fed or fasting status, using transmission electro

Externí odkaz: https://doaj.org/article/404d2c5db08241938901383fabf3f138

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