Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Litong Nie"'
Autor:
Litong Nie, Chao Wang, Min Huang, Xiaoguang Liu, Xu Feng, Mengfan Tang, Siting Li, Qinglei Hang, Hongqi Teng, Xi Shen, Li Ma, Boyi Gan, Junjie Chen
Publikováno v:
eLife, Vol 12 (2024)
Poly(ADP-ribose)ylation or PARylation by PAR polymerase 1 (PARP1) and dePARylation by poly(ADP-ribose) glycohydrolase (PARG) are equally important for the dynamic regulation of DNA damage response. PARG, the most active dePARylation enzyme, is recrui
Externí odkaz:
https://doaj.org/article/92e85ce7326f405eb84500e2b50e7d5b
Autor:
Shengzhe Zhang, Sung Ho Lee, Litong Nie, Yuanjian Huang, Gengyi Zou, Youn‐Sang Jung, Sohee Jun, Jie Zhang, Esther M. Lien, Junjie Chen, Jae‐Il Park
Publikováno v:
Cancer Communications, Vol 43, Iss 1, Pp 159-163 (2023)
Externí odkaz:
https://doaj.org/article/f5ab10a75cbc4938a7ae90dba61d3d84
Autor:
Qinglei Hang, Liyong Zeng, Li Wang, Litong Nie, Fan Yao, Hongqi Teng, Yalan Deng, Shannon Yap, Yutong Sun, Steven J. Frank, Junjie Chen, Li Ma
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
The molecular mechanisms underlying cancer cell radioresistance need to be elucidated. In this study, the authors show that the microRNA biogenesis factor DGCR8 is stabilized by USP51 and ATM upon irradiation and by consequence it promotes the repair
Externí odkaz:
https://doaj.org/article/840fee3496b548828dc6ab49a766f66c
Publikováno v:
MedComm, Vol 2, Iss 4, Pp 855-857 (2021)
Externí odkaz:
https://doaj.org/article/f970423ba48b49aeb84eeff9af96f8ff
Autor:
Yilei Zhang, Robert V. Swanda, Litong Nie, Xiaoguang Liu, Chao Wang, Hyemin Lee, Guang Lei, Chao Mao, Pranavi Koppula, Weijie Cheng, Jie Zhang, Zhenna Xiao, Li Zhuang, Bingliang Fang, Junjie Chen, Shu-Bing Qian, Boyi Gan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Glutathione peroxidase 4 (GPX4) inhibits ferroptosis, but protein synthesis is inefficient and costly. Here, the authors reveal that cystine uptake promotes GPX4 synthesis by activating mTORC1 and show that cancer cells are sensitized to ferroptosis
Externí odkaz:
https://doaj.org/article/f3ac49c7fb974751a3e7aab804b7d325
Autor:
Jeong-Min Park, Huimin Zhang, Litong Nie, Chao Wang, Min Huang, Xu Feng, Mengfan Tang, Zhen Chen, Yun Xiong, Namsoo Lee, Siting Li, Ling Yin, Traver Hart, Junjie Chen
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6545 (2023)
Etoposide (ETO) is an anticancer drug that targets topoisomerase II (TOP2). It stabilizes a normally transient TOP2–DNA covalent complex (TOP2cc), thus leading to DNA double-strand breaks (DSBs). Tyrosyl-DNA phosphodiesterases two (TDP2) is directl
Externí odkaz:
https://doaj.org/article/6c3609d1e8ed4e23bcc0a7e89023a8de
Autor:
Xu Feng, Chang Yang, Yuanjian Huang, Su, Dan, Chao Wang, Wilson, Lori Lyn, Ling Yin, Mengfan Tang, Siting Li, Zhen Chen, Dandan Zhu, Shimin Wang, Shengzhe Zhang, Jie Zhang, Huimin Zhang, Litong Nie, Min Huang, Jae-Il Park, Hart, Traver, Jiang, Dadi
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 9/24/2024, Vol. 121 Issue 39, p1-11, 35p
Autor:
Xiaoguang Liu, Litong Nie, Yilei Zhang, Yuelong Yan, Chao Wang, Medina Colic, Kellen Olszewski, Amber Horbath, Xiong Chen, Guang Lei, Chao Mao, Shiqi Wu, Li Zhuang, Masha V. Poyurovsky, M. James You, Traver Hart, Daniel D. Billadeau, Junjie Chen, Boyi Gan
Publikováno v:
Nature Cell Biology. 25:404-414
Autor:
Jae-Il Park, Shengzhe Zhang, Sung Ho Lee, Litong Nie, Yuanjian Huang, Gengyi Zou, Youn-Sang Jung, Sohee Jun, Jie Zhang, Esther Lien, Junjie Chen
Publikováno v:
Cancer Communications. 43:159-163
Lysosomes play vital roles in the degradation and recycling of various macromolecules, protein secretion, energy metabolism, and cell signaling. Increasing evidence suggests that the deregulated lysosomes contribute to tumorigenesis and therapeutic r
Autor:
Meiyu Geng, Jian Ding, Xun Huang, Hong Liu, Minjia Tan, Min Huang, Mingyue Zheng, Aijun Shen, Linjiang Tong, Litong Nie, Jiang Wang, Yuan Xu, Danni Sun, Qiuming Pan, Xuhong Fu, Juan Yan, Xiaoyang Dai
Supplementary Table S2 shows the effect of aspirin on MDA-MB-231 lung metastasis in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27f46aeca02906eedcff63afd936fad3
https://doi.org/10.1158/1078-0432.22462965.v1
https://doi.org/10.1158/1078-0432.22462965.v1