Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Liting Zhai"'
Autor:
Ning Zhang, Liting Zhai, Ronald Man Yeung Wong, Can Cui, Sheung-Wai Law, Simon Kwoon-Ho Chow, Stuart B. Goodman, Wing-Hoi Cheung
Publikováno v:
Immunity & Ageing, Vol 21, Iss 1, Pp 1-16 (2024)
Abstract Sarcopenia is a complex age-associated syndrome of progressive loss of muscle mass and strength. Although this condition is influenced by many factors, age-related changes in immune function including immune cell dynamics, and chronic inflam
Externí odkaz:
https://doaj.org/article/38b35da14abd4113aea8418d3056eefe
Autor:
Liting Zhai, Amber C Bonds, Clyde A Smith, Hannah Oo, Jonathan Chiu-Chun Chou, Paula V Welander, Laura MK Dassama
Publikováno v:
eLife, Vol 12 (2024)
Sterol lipids are widely present in eukaryotes and play essential roles in signaling and modulating membrane fluidity. Although rare, some bacteria also produce sterols, but their function in bacteria is not known. Moreover, many more species, includ
Externí odkaz:
https://doaj.org/article/e3634701c7d94cabb207e3d7c545c3db
Autor:
Miaomiao Shen, Nalini Dhingra, Quan Wang, Chen Cheng, Songbiao Zhu, Xiaolin Tian, Jun Yu, Xiaoxin Gong, Xuzhichao Li, Hongwei Zhang, Xin Xu, Liting Zhai, Min Xie, Ying Gao, Haiteng Deng, Yongning He, Hengyao Niu, Xiaolan Zhao, Song Xiang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Rad5 is a hub connecting three replication stress tolerance pathways. Here, the authors present the 3.3 Å crystal structure of a N-terminal truncated K.lactis Rad5 construct that reveals the spatial arrangement of the HIRAN, Snf2 and RING domains an
Externí odkaz:
https://doaj.org/article/fffc4fbf2bca4bedb24e1f3731229166
Autor:
Jennifer Friedman, Desiree E. Smith, Mahmoud Y. Issa, Valentina Stanley, Rengang Wang, Marisa I. Mendes, Meredith S. Wright, Kristen Wigby, Amber Hildreth, John R. Crawford, Alanna E. Koehler, Shimul Chowdhury, Shareef Nahas, Liting Zhai, Zhiwen Xu, Wing-Sze Lo, Kiely N. James, Damir Musaev, Andrea Accogli, Kether Guerrero, Luan T. Tran, Tarek E. I. Omar, Tawfeg Ben-Omran, David Dimmock, Stephen F. Kingsmore, Gajja S. Salomons, Maha S. Zaki, Geneviève Bernard, Joseph G. Gleeson
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Valyl-tRNA synthetase (VARS) charges valyl-tRNA with the amino acid valine, required for translation. Here, the authors describe a progressive epileptic encephalopathy in individuals from five families carrying biallelic mutations in the VARS gene th
Externí odkaz:
https://doaj.org/article/2b11aa05a4174343ac7596764303089f
Publikováno v:
Applied Sciences, Vol 12, Iss 15, p 7427 (2022)
Remote sensing estimation of crop nitrogen content allows real-time monitoring of growth to develop scientific methods. However, most of the current remote sensing estimates of crop nitrogen contents have limitations in accurately reflecting the vert
Externí odkaz:
https://doaj.org/article/9d83493c79cc438ab903b0babd7a86e9
Publikováno v:
Biochemical and Biophysical Research Communications. 624:89-94
The human VPS10 domain-containing receptor SorCS3 belongs to the Vps10p-domain receptor family and is an important receptor for regulating normal cellular functions via protein sorting. Here, we determined the cryo-EM structure of the full-length Sor
Publikováno v:
ChemBioChem.
Publikováno v:
Biochemical and Biophysical Research Communications. 600:75-79
Sorting-related receptor with A-type repeats (SORLA) is an important receptor for regulating normal cellular functions via protein sorting. Here, we determined the structures of the full-length SORLA and identified two distinct conformations of apo-S
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Debranching of glycogen is an important step in its use as an energy source. Here, the authors describe the crystal structures of glycogen debranching enzyme alone and in complex with oligosaccharides and provide molecular insights into the function,
Externí odkaz:
https://doaj.org/article/6f02788bb1894b07b2fa0be196a97505
Autor:
Maolu Yin, Manizheh Izadi, Karin Tenglin, Thibault Viennet, Liting Zhai, Ge Zheng, Haribabu Arthanari, Laura M. K. Dassama, Stuart H. Orkin
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Transcription factors (TFs) control numerous genes that are directly relevant to many human disorders. However, developing specific reagents targeting TFs within intact cells is challenging due to the presence of highly disordered regions within thes