Genetic variants associated with response to lithium treatment in bipolar disorder:a genome-wide association study

Autor: Ryota Hashimoto, Andrea Hofmann, Gustavo Turecki, N. Lackner, Philip B. Mitchell, Bárbara Arias, Urban Ösby, J. Raymond DePaulo, Martin Alda, Julie Garnham, Esther Jiménez, Abesh Kumar Bhattacharjee, Peter P. Zandi, Clara Brichant-Petitjean, Frank Bellivier, Marina Mitjans, Palmiero Monteleone, Eduard Vieta, Liping Hou, Eva Z. Reininghaus, Raffaella Ardau, Paul D. Shilling, Mazda Adli, Armin Birner, Marion Leboyer, Lena Backlund, Andreas J. Forstner, David A. Cousins, Francesc Colom, Catharina Lavebratt, K Oliver Schubert, Barbara W. Schweizer, Mario Maj, Kazufumi Akiyama, Antoni Benabarre, Julia Volkert, Alessio Squassina, Marcella Rietschel, Stephanie H. Witt, Gonzalo Laje, Louise Frisén, Jordan W. Smoller, Paul Grof, Tomas Novak, L. Trevor Young, Sven Cichon, Bruno Etain, Ichiro Kusumi, Sarah K. Tighe, Sarah Kittel-Schneider, Florian Seemüller, Jean-Pierre Kahn, Markus M. Nöthen, Tadafumi Kato, Alexandre Dayer, Caroline M. Nievergelt, Mirko Manchia, Francis J. McMahon, Peter R. Schofield, Susanne Bengesser, Po-Hsiu Kuo, Stefan Herms, Scott R. Clark, Piotr M. Czerski, Oliver Gruber, Franziska Degenhardt, Mark A. Frye, Joanna M. Biernacka, Christian Simhandl, Guo-Bo Chen, Adam Wright, Sébastien Gard, Peter Falkai, Carlos Jaramillo, Stéphane Jamain, Roy H. Perlis, Andrea Pfennig, Tatyana Shekhtman, Maria Del Zompo, Clarissa de Rosalmeida Dantas, Thomas G. Schulze, Alfonso Tortorella, Francis M. Mondimore, John R. Kelsoe, Jean-Michel Aubry, Mikael Landén, Andreas Reif, Naomi R. Wray, Martin Schalling, Janice M. Fullerton, Nirmala Akula, Claudio E. M. Banzato, Elise T. Bui, Per Hoffmann, Sebastian Kliwicki, Guy A. Rouleau, Maria Grigoroiu-Serbanescu, Glenda MacQueen, Lina Martinsson, Giovanni Severino, Norio Ozaki, Daniela Reich-Erkelenz, Layla Kassem, Manuel Mattheisen, Pavla Stopkova, Michael Bauer, Caterina Chillotti, Kazutaka Shimoda, Bernhard T. Baune, Janusz K. Rybakowski, Thomas Stamm, Joanna Hauser, Fernando S. Goes, Urs Heilbronner, James B. Potash, Susan L. McElroy, Barbara König, Susan G. Leckband, Michael McCarthy, Hsi-Chung Chen, Claire Slaney, Cristiana Cruceanu, Pablo Cervantes

Publikováno v: Hou, L, Heilbronner, U, Degenhardt, F, Adli, M, Akiyama, K, Akula, N, Ardau, R, Arias, B, Backlund, L, Banzato, C E M, Benabarre, A, Bengesser, S, Bhattacharjee, A K, Biernacka, J M, Birner, A, Brichant-Petitjean, C, Bui, E T, Cervantes, P, Chen, G-B, Chen, H-C, Chillotti, C, Cichon, S, Clark, S R, Colom, F, Cousins, D A, Cruceanu, C, Czerski, P M, Dantas, C R, Dayer, A, Étain, B, Falkai, P, Forstner, A J, Frisén, L, Fullerton, J M, Gard, S, Garnham, J S, Goes, F S, Grof, P, Gruber, O, Hashimoto, R, Hauser, J, Herms, S, Hoffmann, P, Hofmann, A, Jamain, S, Jiménez, E, Kahn, J-P, Kassem, L, Kittel-Schneider, S, Kliwicki, S, König, B, Kusumi, I, Lackner, N, Laje, G, Landén, M, Lavebratt, C, Leboyer, M, Leckband, S G, Jaramillo, C A L, MacQueen, G, Manchia, M, Martinsson, L, Mattheisen, M, McCarthy, M J, McElroy, S L, Mitjans, M, Mondimore, F M, Monteleone, P, Nievergelt, C M, Nöthen, M M, Ösby, U, Ozaki, N, Perlis, R H, Pfennig, A, Reich-Erkelenz, D, Rouleau, G A, Schofield, P R, Schubert, K O, Schweizer, B W, Seemüller, F, Severino, G, Shekhtman, T, Shilling, P D, Shimoda, K, Simhandl, C, Slaney, C M, Smoller, J W, Squassina, A, Stamm, T, Stopkova, P, Tighe, S K, Tortorella, A, Turecki, G, Volkert, J, Witt, S, Wright, A, Young, L T, Zandi, P P, Potash, J B, DePaulo, J R, Bauer, M, Reininghaus, E Z, Novák, T, Aubry, J-M, Maj, M, Baune, B T, Mitchell, P B, Vieta, E, Frye, M A, Rybakowski, J K, Kuo, P-H, Kato, T, Grigoroiu-Serbanescu, M, Reif, A, Del Zompo, M, Bellivier, F, Schalling, M, Wray, N R, Kelsoe, J R, Alda, M, Rietschel, M, McMahon, F J & Schulze, T G 2016, ' Genetic variants associated with response to lithium treatment in bipolar disorder : a genome-wide association study ', The Lancet, vol. 387, no. 10023, pp. 1085-93 . https://doi.org/10.1016/S0140-6736(16)00143-4
Lancet (London, England)
The Lancet, Vol. 387, No 10023 (2016) pp. 1085-1093

BACKGROUND: Lithium is a first-line treatment in bipolar disorder, but individual response is variable. Previous studies have suggested that lithium response is a heritable trait. However, no genetic markers of treatment response have been reproducib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea414119edbeb65336dd427c7904c59b
https://pure.au.dk/portal/da/publications/genetic-variants-associated-with-response-to-lithium-treatment-in-bipolar-disorder(2fa779f5-c756-4c05-bf5d-abdc7d4f90e9).html

Lithium: updated human knowledge using an evidence-based approach: Part I: Clinical efficacy in bipolar disorder

Autor: Grandjean, Etienne Marc, Aubry, Jean-Michel

Publikováno v: CNS Drugs, Vol. 23, No 3 (2009) pp. 225-240

Although there has been a decrease in lithium use over several years, it is still recommended as a first-line mood stabilizer in all recent guidelines. It has been argued that many studies of lithium were conducted at a time when study design, assess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1400::4af620cf7917ff485001c6afb53b64a8
https://archive-ouverte.unige.ch/unige:19534

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