Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Lite Ge"'
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 9, p 340 (2024)
Background: Alzheimer's disease (AD) poses a significant public health challenge, increasingly affecting patients' finances, mental health, and functional abilities as the global population ages. Stem cell-derived extracellular vesicles (SC-EVs) have
Externí odkaz:
https://doaj.org/article/3f9f6a1724474e47a49354ef3f836018
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionIntracerebral hemorrhage (ICH) often triggers oxidative stress through reactive oxygen species (ROS). Transforming growth factor-β-activated kinase 1 (TAK1) plays a pivotal role in regulating oxidative stress and inflammation across vari
Externí odkaz:
https://doaj.org/article/91fc8e5b1b2c47e5a0ae1c5adcf84a13
Publikováno v:
Heliyon, Vol 10, Iss 3, Pp e25050- (2024)
Background: Bone-marrow-derived mesenchymal stromal (stem) cells [also called MSC(M)] and their extracellular vesicles (EVs) are considered a potentially innovative form of therapy for traumatic brain injury (TBI). Nevertheless, their application to
Externí odkaz:
https://doaj.org/article/07fc7a3e49d84d708981e0da304d6ce5
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract Background Extracellular vesicles derived from stem cells (SC-EVs) have been proposed as a novel therapy for ischemic stroke. However, their effects remain incompletely understood. Therefore, we conducted this meta-analysis to systematically
Externí odkaz:
https://doaj.org/article/fab2d2f417364b249286692a89bc8ec6
Autor:
Lite Ge, Chengfeng Xun, Wenshui Li, Shengyu Jin, Zuo Liu, Yi Zhuo, Da Duan, Zhiping Hu, Ping Chen, Ming Lu
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-23 (2021)
Abstract Mesenchymal stem cells (MSCs) play important roles in tissue repair and regeneration, such as the induction of angiogenesis, particularly under hypoxic conditions. However, the molecular mechanisms underlying hypoxic MSC activation remain la
Externí odkaz:
https://doaj.org/article/95b4e27af0c640caa3e19812edc853a0
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionExtracellular vesicles (EVs), especially mesenchymal stem (stromal) cell-derived EVs (MSC-EVs), have gained attention as potential novel treatments for multiple sclerosis (MS). However, their effects remain incompletely understood. Thus,
Externí odkaz:
https://doaj.org/article/83910436340a442780838b8e515999fb
Autor:
Jianyang Liu, Jialin He, Lite Ge, Han Xiao, Yan Huang, Liuwang Zeng, Zheng Jiang, Ming Lu, Zhiping Hu
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-17 (2021)
Abstract Background Intracerebral hemorrhage (ICH) is a major public health concern, and mesenchymal stem cells (MSCs) hold great potential for treating ICH. However, the quantity and quality of MSCs decline in the cerebral niche, limiting the potent
Externí odkaz:
https://doaj.org/article/6e352c9a65c543238d6f3958c10f1e91
Effect of Bone Marrow Mesenchymal Stromal Cell Therapies in Rodent Models of Sepsis: A Meta-Analysis
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
BackgroundMultiple preclinical studies have demonstrated that bone‐marrow derived mesenchymal stromal (stem) cells [MSC(M)] positively influence the severity of sepsis symptoms and mortality in rodent models. However, this remains an inconclusive f
Externí odkaz:
https://doaj.org/article/3f43129121e3418cbf8f9695160c36a0
Autor:
Chengfeng Xun, Lite Ge, Feng Tang, Lu Wang, Yi Zhuo, Lang Long, Jiaomei Qi, Li Hu, Da Duan, Ping Chen, Ming Lu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 131, Iss , Pp 110584- (2020)
Mesenchymal stromal cells (MSCs) have been used for the treatment of neuronal injury and neurodegenerative diseases. Their underlying mechanism may involve increased secretion of paracrine factors, which promotes tissue repair. Presently, exosomes ha
Externí odkaz:
https://doaj.org/article/42a7a3960b3b42bf8c13cd792ecb3c29
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Mesenchymal stem cells (MSCs) have presented a promising neuroprotective effect in cerebral ischemia/reperfusion (I/R). Olfactory mucosa MSCs (OM-MSCs), a novel source of MSCs located in the human nasal cavity, are easy to obtain and situated for aut
Externí odkaz:
https://doaj.org/article/97b8160d2911448cb519f8bd1f946816