Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Lital Alfonta"'
Autor:
Hezi Hayun, Matt Coban, Ashok Kumar Bhagat, Eden Ozer, Lital Alfonta, Thomas R. Caulfield, Evette S. Radisky, Niv Papo
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Matrix metalloproteinases (MMPs) regulate the degradation of extracellular matrix (ECM) components in biological processes. MMP activity is controlled by natural tissue inhibitors of metalloproteinases (TIMPs) that non-selectively inhibit th
Externí odkaz:
https://doaj.org/article/9302df7774f5463d897a9547d6d88c2a
Autor:
Yonatan Chemla, Michael Peeri, Mathias Luidor Heltberg, Jerry Eichler, Mogens Høgh Jensen, Tamir Tuller, Lital Alfonta
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
The mechanisms for regulating translation re-initiation in bacteria remain poorly understood. Here, the authors screened a library of synthetic operons and identified a ribosome termination structure that modulates re-initiation efficiency and which
Externí odkaz:
https://doaj.org/article/f945cec54ed844a3bf6360085372dfe1
Simplified methodology for a modular and genetically expanded protein synthesis in cell-free systems
Publikováno v:
Synthetic and Systems Biotechnology, Vol 4, Iss 4, Pp 189-196 (2019)
Genetic code expansion, which enables the site-specific incorporation of unnatural amino acids into proteins, has emerged as a new and powerful tool for protein engineering. Currently, it is mainly utilized inside living cells for a myriad of applica
Externí odkaz:
https://doaj.org/article/856329b342164fd4a59955cdb76854cc
Autor:
Eden Ozer, Lital Alfonta
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Escherichia coli has been considered as the most used model bacteria in the majority of studies for several decades. However, a new, faster chassis for synthetic biology is emerging in the form of the fast-growing gram-negative bacterium Vibrio natri
Externí odkaz:
https://doaj.org/article/8398566c058b4e39863a662c26e50d78
Publikováno v:
Sensors, Vol 20, Iss 16, p 4648 (2020)
Pandemics require a fast and immediate response to contain potential infectious carriers. In the recent 2020 Covid-19 worldwide pandemic, authorities all around the world have failed to identify potential carriers and contain it on time. Hence, a rap
Externí odkaz:
https://doaj.org/article/3c427c8d98f7455db08160ba945991ef
Autor:
Dan Bar-Yaacov, Idan Frumkin, Yuka Yashiro, Takeshi Chujo, Yuma Ishigami, Yonatan Chemla, Amit Blumberg, Orr Schlesinger, Philipp Bieri, Basil Greber, Nenad Ban, Raz Zarivach, Lital Alfonta, Yitzhak Pilpel, Tsutomu Suzuki, Dan Mishmar
Publikováno v:
PLoS Biology, Vol 15, Iss 1, p e1002594 (2017)
[This corrects the article DOI: 10.1371/journal.pbio.1002557.].
Externí odkaz:
https://doaj.org/article/d68ebf9c64a34bf3b0db2f6d2a1e4ea8
Autor:
Dan Bar-Yaacov, Idan Frumkin, Yuka Yashiro, Takeshi Chujo, Yuma Ishigami, Yonatan Chemla, Amit Blumberg, Orr Schlesinger, Philipp Bieri, Basil Greber, Nenad Ban, Raz Zarivach, Lital Alfonta, Yitzhak Pilpel, Tsutomu Suzuki, Dan Mishmar
Publikováno v:
PLoS Biology, Vol 14, Iss 9, p e1002557 (2016)
The mitochondrial ribosome, which translates all mitochondrial DNA (mtDNA)-encoded proteins, should be tightly regulated pre- and post-transcriptionally. Recently, we found RNA-DNA differences (RDDs) at human mitochondrial 16S (large) rRNA position 9
Externí odkaz:
https://doaj.org/article/b0b5d25bb08e4ce4a5914113f537bc16
Publikováno v:
Proceedings, Vol 1, Iss 8, p 715 (2017)
Biosensing efficiency, selectivity and sensitivity rely first and foremost on a successful interfacing between enzymes and sensing interfaces. [...]
Externí odkaz:
https://doaj.org/article/731634c8b2b64bc7b90dc7fffbb55a6e
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67333 (2013)
The ability to site-specifically incorporate unnatural amino acids (UAAs) into proteins is a powerful tool in protein engineering. While dozens of UAAs have been successfully introduced into proteins expressed by Escherichia coli cells, it has been m
Externí odkaz:
https://doaj.org/article/4b8809d54b4640e6b3508922e84688b4
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68363 (2013)
Using a commercial protein expression system, we sought the crucial elements and conditions for the expression of proteins with genetically encoded unnatural amino acids. By identifying the most important translational components, we were able to inc
Externí odkaz:
https://doaj.org/article/e26b4332142c43d582eb7c8219bc73ef