Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Lital, Adler"'
Autor:
Wei Jiang, James R. Birtley, Shu-Chen Hung, Weiqi Wang, Shin-Heng Chiou, Claudia Macaubas, Birgitte Kornum, Lu Tian, Huang Huang, Lital Adler, Grant Weaver, Liying Lu, Alexandra Ilstad-Minnihan, Sriram Somasundaram, Sashi Ayyangar, Mark M. Davis, Lawrence J. Stern, Elizabeth D. Mellins
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
T cells from narcolepsy patients were recently reported to recognize hypocretin, a wakefulness-promoting neurohormone, suggesting autoimmune origin of the disease. Here the authors show that hypocretin-specific T cells expand both in healthy controls
Externí odkaz:
https://doaj.org/article/c167c2cc9a574287872bf608f7e73845
Autor:
Ayelet Erez, Eytan Ruppin, Igor Ulitsky, Sandesh C.S. Nagamani, Yair Anikster, Raya Eilam, Ben Pode-Shakked, Yehudit Zaltsman-Amir, Keren Bahar Halpern, Erez Persi, Sivan Galai, Noa Stettner, Julia Frug, Alona Sarver, Rom Keshet, Joo Sang Lee, Lital Adler, Shiran Rabinovich, Adi Jacob, Odeya Boukobza Assayag, Omer Goldman, Alon Silberman
Supplementary Figures 1-5 further support our findings regarding the contribution to the maintenance of intracellular pH for ASS1 downregulated cancer cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bf590f6c6dae26b958754b6195138c9
https://doi.org/10.1158/0008-5472.22422482
https://doi.org/10.1158/0008-5472.22422482
Autor:
Ayelet Erez, Eytan Ruppin, Igor Ulitsky, Sandesh C.S. Nagamani, Yair Anikster, Raya Eilam, Ben Pode-Shakked, Yehudit Zaltsman-Amir, Keren Bahar Halpern, Erez Persi, Sivan Galai, Noa Stettner, Julia Frug, Alona Sarver, Rom Keshet, Joo Sang Lee, Lital Adler, Shiran Rabinovich, Adi Jacob, Odeya Boukobza Assayag, Omer Goldman, Alon Silberman
Downregulation of the urea cycle enzyme argininosuccinate synthase (ASS1) by either promoter methylation or by HIF1α is associated with increased metastasis and poor prognosis in multiple cancers. We have previously shown that in normoxic conditions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a0c71bc872afa3968a802eb42fd39f4
https://doi.org/10.1158/0008-5472.c.6511238.v1
https://doi.org/10.1158/0008-5472.c.6511238.v1
Autor:
Wei Jiang, James R. Birtley, Shu-Chen Hung, Weiqi Wang, Shin-Heng Chiou, Claudia Macaubas, Birgitte Kornum, Lu Tian, Huang Huang, Lital Adler, Grant Weaver, Liying Lu, Alexandra Ilstad-Minnihan, Sriram Somasundaram, Sashi Ayyangar, Mark M. Davis, Lawrence J. Stern, Elizabeth D. Mellins
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/96aacd3a26fb4821be774590097d0eaa
Autor:
Justin Lee, Hanson Tam, Lital Adler, Alexandra Ilstad-Minnihan, Claudia Macaubas, Elizabeth D Mellins
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183594 (2017)
Monocytes play a critical role in the innate and adaptive immune systems, performing phagocytosis, presenting antigen, and producing cytokines. They are a heterogeneous population that has been divided in humans into classical, intermediate, and non-
Externí odkaz:
https://doaj.org/article/a4b40b743f1740e9854b1dc50c6bda71
Autor:
Shaul, Lerner, Raya, Eilam, Lital, Adler, Julien, Baruteau, Topaz, Kreiser, Michael, Tsoory, Alexander, Brandis, Tevie, Mehlman, Mina, Ryten, Juan A, Botia, Sonia Garcia, Ruiz, Alejandro Cisterna, Garcia, Carlo, Dionisi-Vici, Giusy, Ranucci, Marco, Spada, Ram, Mazkereth, Robert, McCarter, Rima, Izem, Thomas J, Balmat, Rachel, Richesson, Ehud, Gazit, Sandesh C S, Nagamani, Marc, Yudkoff
Publikováno v:
Human Genetics
Argininosuccinate lyase (ASL) is essential for the NO-dependent regulation of tyrosine hydroxylase (TH) and thus for catecholamine production. Using a conditional mouse model with loss of ASL in catecholamine neurons, we demonstrate that ASL is expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b55b04fcb401eba776e6c8db6bbac0e0
https://pubmed.ncbi.nlm.nih.gov/34417872
https://pubmed.ncbi.nlm.nih.gov/34417872
Autor:
Hadas Landesman, Ayelet Erez, Omer Goldman, Sergey Malitsky, Sivan Galai, Alexander Brandis, Tevi Mehlman, Keyur Talsania, S. Eleonore Koehler, Yael Kuperman, Eytan Ruppin, Lisha Qiu Jin Lim, Igor Ulitsky, Angel Porgador, Yongmei Zhao, Roni Oren, Shaul Lerner, Joo Sang Lee, Maxim Itkin, Hila Weiss Tishler, Rotem Katzir, Shiran Rabinovich, Nir Peled, Noa Stettner, Lital Adler, Yuri Kuznetsov, Rom Keshet, Muhammed Iraqi, Tsai-wei Shen, Yarden Ariav
Publikováno v:
Nature Cancer
Nature Cancer, 1(9), 894-908. Nature Publishing Group
Nature Cancer, 1(9), 894-908. Nature Publishing Group
Argininosuccinate synthase (ASS1) downregulation in different tumors has been shown to support cell proliferation and yet, in several common cancer subsets ASS1 expression associates with poor patient prognosis. Here we demonstrate that ASS1 expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::193f750c2610f8dd4d6709f2a1e2b1be
Autor:
David Dimmock, Efrat Ben-Zeev, Ayelet Erez, Ziv Porat, Maxim Itkin, Sergey Malitsky, Inbal Geva, Shiran Rabinovich, Amir Bahat, Adam H. Buchaklian, Shani Agron, Smadar Levin-Zaidman, Lital Adler, Alon Silberman, Daniel Helbling
Publikováno v:
Oncogene
Oncogene, Nature Publishing Group, 2019, ⟨10.1038/s41388-019-0976-2⟩
Oncogene, Nature Publishing Group, 2019, ⟨10.1038/s41388-019-0976-2⟩
International audience; Citrin, encoded by SLC25A13 gene, is an inner mitochondrial transporter that is part of the malate–aspartate shuttle, which regulates the NAD+/NADH ratio between the cytosol and mitochondria. Citrullinemia type II (CTLN-II)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e089e7d1fe9217c56d98fe5c483c7e0f
https://hal.archives-ouvertes.fr/hal-02309334
https://hal.archives-ouvertes.fr/hal-02309334
Autor:
Noa Stettner, Miguel Unda, Noam Stern-Ginossar, Eytan Ruppin, Ayelet Erez, Lilach Agemy, Yardena Samuels, Eilon Barnea, Daniel Helbling, Sandesh C.S. Nagamani, Hiren Karathia, Alon Silberman, Noam Auslander, David Dimmock, Hila Weiss, Joo Sang Lee, Qin Sun, Shelly Kalaora, Avigdor Scherz, Sergey Malitsky, Sivan Pinto, David M. Wilson, Rom Keshet, Arie Admon, Arkaitz Carracedo, Lital Adler, Sridhar Hannenhalli, Maxim Itkin, Ronen Levy, Shiran Rabinovich, Alexander Brandis, Ronit Elhasid, Narin Carmel, Raya Eilam
The urea cycle (UC) is the main pathway by which mammals dispose of waste nitrogen. We find that specific alterations in the expression of most UC enzymes occur in many tumors, leading to a general metabolic hallmark termed "UC dysregulation" (UCD).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4060032e98d88233c111c825e65ae77b
https://zenodo.org/record/3616765
https://zenodo.org/record/3616765
Autor:
Simon, Raffel, Mattia, Falcone, Niclas, Kneisel, Jenny, Hansson, Wei, Wang, Christoph, Lutz, Lars, Bullinger, Gernot, Poschet, Yannic, Nonnenmacher, Andrea, Barnert, Carsten, Bahr, Petra, Zeisberger, Adriana, Przybylla, Markus, Sohn, Martje, Tönjes, Ayelet, Erez, Lital, Adler, Patrizia, Jensen, Claudia, Scholl, Stefan, Fröhling, Sibylle, Cocciardi, Patrick, Wuchter, Christian, Thiede, Anne, Flörcken, Jörg, Westermann, Gerhard, Ehninger, Peter, Lichter, Karsten, Hiller, Rüdiger, Hell, Carl, Herrmann, Anthony D, Ho, Jeroen, Krijgsveld, Bernhard, Radlwimmer, Andreas, Trumpp
Publikováno v:
Nature. 560(7718)
In Extended Data Fig. 1a of this Letter, the flow cytometry plot depicting the surface phenotype of AML sample DD08 was a duplicate of the plot for AML sample DD06. Supplementary Data 4 has been added to the Supplementary Information of the original
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::898b3358465737146714ba41d5ad6159
https://pubmed.ncbi.nlm.nih.gov/29144447
https://pubmed.ncbi.nlm.nih.gov/29144447