Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Lissette Gomez"'
Autor:
Wei Zhang, Juan I. Young, Lissette Gomez, Michael A. Schmidt, David Lukacsovich, Achintya Varma, X. Steven Chen, Brian Kunkle, Eden R. Martin, Lily Wang
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
ABSTRACTDNA methylation (DNAm) plays a crucial role in a number of complex diseases. However, the reliability of DNAm levels measured using Illumina arrays varies across different probes. Previous research primarily assessed probe reliability by comp
Externí odkaz:
https://doaj.org/article/4ce06caaeaea44738879447256113558
Autor:
Wei Zhang, Juan I. Young, Lissette Gomez, Michael A. Schmidt, David Lukacsovich, Achintya Varma, X. Steven Chen, Eden R. Martin, Lily Wang
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-19 (2023)
Abstract Background Growing evidence has demonstrated that DNA methylation (DNAm) plays an important role in Alzheimer’s disease (AD) and that DNAm differences can be detected in the blood of AD subjects. Most studies have correlated blood DNAm wit
Externí odkaz:
https://doaj.org/article/ae8faa0469a948dca7ff5ab04c03229a
Autor:
Tiago C. Silva, Wei Zhang, Juan I. Young, Lissette Gomez, Michael A. Schmidt, Achintya Varma, X. Steven Chen, Eden R. Martin, Lily Wang
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-21 (2022)
Abstract Background Sex is increasingly recognized as a significant factor contributing to the biological and clinical heterogeneity in AD. There is also growing evidence for the prominent role of DNA methylation (DNAm) in Alzheimer’s disease (AD).
Externí odkaz:
https://doaj.org/article/673535fab72c471f815ef846cc8b2bcd
Autor:
Tiago C. Silva, Juan I. Young, Lanyu Zhang, Lissette Gomez, Michael A. Schmidt, Achintya Varma, X. Steven Chen, Eden R. Martin, Lily Wang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
DNA methylation differences in Alzheimer’s disease have been previously reported, although the interpretation of the differences is unclear. Here, the authors performed epigenome-wide meta-analyses of DNA methylation in blood and brain, and develop
Externí odkaz:
https://doaj.org/article/43df6e2bbc7a4b2eb04e9c03de3ff40c
Autor:
Lanyu Zhang, Juan I. Young, Lissette Gomez, Tiago C. Silva, Michael A. Schmidt, Jesse Cai, Xi Chen, Eden R. Martin, Lily Wang
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-19 (2021)
Abstract Sex is an important factor that contributes to the clinical and biological heterogeneities in Alzheimer’s disease (AD), but the regulatory mechanisms underlying sex disparity in AD are still not well understood. DNA methylation is an impor
Externí odkaz:
https://doaj.org/article/b16257ff2a924aee807bd7152bb0083d
Autor:
Lanyu Zhang, Tiago C. Silva, Juan I. Young, Lissette Gomez, Michael A. Schmidt, Kara L. Hamilton-Nelson, Brian W. Kunkle, Xi Chen, Eden R. Martin, Lily Wang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Previous studies have identified DNA methylation changes in Alzheimer’s disease. Here the authors perform a meta-analysis of DNA methylation datasets to identify epigenetic correlates of Alzheimer’s disease in the prefrontal cortex.
Externí odkaz:
https://doaj.org/article/10b8fdb57de148668868987456aca968
Autor:
Ashley H Beecham, Lilyana Amezcua, Angel Chinea, Clara P Manrique, Lissette Gomez, Andrea Martinez, Gary W Beecham, Nikolaos A Patsopoulos, Tanuja Chitnis, Howard L Weiner, Philip L De Jager, Esteban G Burchard, Brett T Lund, Kathryn C Fitzgerald, Peter A Calabresi, Silvia R Delgado, Jorge R Oksenberg, Jacob L McCauley
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0279132 (2022)
The Major Histocompatibility Complex (MHC) makes the largest genetic contribution to multiple sclerosis (MS) susceptibility, with 32 independent effects across the region explaining 20% of the heritability in European populations. Variation is high a
Externí odkaz:
https://doaj.org/article/2a71d7c0f97a4ee9840c19b2575059f4
Autor:
Soroosh Noorbakhsh, Lissette Gomez, Yoo Joung, Courtney Meyer, Dustin S. Hanos, Mari Freedberg, Nathan Klingensmith, April A. Grant, Deepika Koganti, Jonathan Nguyen, Randi N. Smith, Jason D. Sciarretta
Publikováno v:
Vascular and Endovascular Surgery. :153857442311651
Purpose Hepatic arterioportal fistula (HAPF) is an uncommon complication of hepatic trauma, which can manifest with abdominal pain and the sequelae of portal hypertension months to years after injury. The purpose of this study is to present cases of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95e91a6fddc993307a0fd34a8b17d270
https://doi.org/10.1177/15385744231165155
https://doi.org/10.1177/15385744231165155
Autor:
Tiago C. Silva, Juan I. Young, Lanyu Zhang, Lissette Gomez, Michael A. Schmidt, Achintya Varma, X. Steven Chen, Eden R. Martin, Lily Wang
We performed a meta-analysis of two large independent blood-based Alzheimer’s disease (AD) epigenome-wide association studies, the ADNI and AIBL studies, and identified 5 CpGs, mapped to the SPIDR, CDH6 genes, and intergenic regions, that were sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4786ce7f77593d9847527e0d939eb70
https://doi.org/10.1101/2022.04.11.22273748
https://doi.org/10.1101/2022.04.11.22273748
Autor:
Lily Wang, Lanyu Zhang, Juan Young, Lissette Gomez, Tiago C Silva, Michael A. Schmidt, Zixi Cai, Brian W. Kunkle, Eden R Martin
Publikováno v:
Alzheimer's & Dementia. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66698c808d5fed1756bc30ced0eef1cb
https://doi.org/10.1002/alz.049363
https://doi.org/10.1002/alz.049363