Zobrazeno 1 - 10 of 368 pro vyhledávání: '"Lismont S"'
1
Akademický článek
Development of quality indicators for hypertension, extractable from the electronic health record of the general practitioner: a rand-modified Delphi method.
Autor: Danhieux K; Family Medicine and Population Health, University of Antwerp, Antwerp, Belgium. Katrien.danhieux@uantwerpen.be., Hollevoet M; Department of Public Health and Primary Care, KU Leuven, Louvain, Belgium., Lismont S; Department of Public Health and Primary Care, KU Leuven, Louvain, Belgium., Taveirne P; Department of Public Health and Primary Care, KU Leuven, Louvain, Belgium., Van Vaerenbergh L; Department of Public Health and Primary Care, KU Leuven, Louvain, Belgium., Vaes B; Department of Public Health and Primary Care, KU Leuven, Louvain, Belgium., Van den Bulck S; Department of Public Health and Primary Care, KU Leuven, Louvain, Belgium.; Research Group Healthcare and Ethics, UHasselt, Hasselt, Belgium.
Publikováno v: BMC primary care [BMC Prim Care] 2024 Aug 15; Vol. 25 (1), pp. 305. Date of Electronic Publication: 2024 Aug 15.
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2
Akademický článek
Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling.
Autor: Zoltowska KM; VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium., Das U; Department of Neurosciences, University of California San Diego, La Jolla, United States., Lismont S; VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium., Enzlein T; VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium.; Center for Mass Spectrometry and Optical Spectroscopy (CeMOS), Mannheim University of Applied Sciences, Mannheim, Germany., Maesako M; Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Charlestown, United States., Houser MCQ; Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Charlestown, United States., Franco ML; Molecular Basis of Neurodegeneration Unit, Instituto de Biomedicina de Valencia, Valencia, Spain., Özcan B; VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium., Gomes Moreira D; VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium., Karachentsev D; Department of Neurosciences, University of California San Diego, La Jolla, United States., Becker A; Department of Neurosciences, University of California San Diego, La Jolla, United States., Hopf C; Center for Mass Spectrometry and Optical Spectroscopy (CeMOS), Mannheim University of Applied Sciences, Mannheim, Germany.; Medical Faculty, Heidelberg University, Heidelberg, Germany.; Mannheim Center for Translational Neuroscience (MCTN), Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany., Vilar M; Molecular Basis of Neurodegeneration Unit, Instituto de Biomedicina de Valencia, Valencia, Spain., Berezovska O; Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Charlestown, United States., Mobley W; Department of Neurosciences, University of California San Diego, La Jolla, United States., Chávez-Gutiérrez L; VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium.
Publikováno v: ELife [Elife] 2024 Jul 19; Vol. 12. Date of Electronic Publication: 2024 Jul 19.
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3
Akademický článek
Apo and Aβ46-bound γ-secretase structures provide insights into amyloid-β processing by the APH-1B isoform.
Autor: Odorčić I; Center for Structural Biology, VIB, Brussels, Belgium.; Structural Biology Brussels, Department of Bioengineering Sciences, Vrije Universiteit Brussel, Brussels, Belgium.; VIB-KU Leuven Center for Brain & Disease Research, Herestraat 49 box 602, 3000, Leuven, Belgium.; Department of Neurosciences, Leuven Brain Institute, KU Leuven, Herestraat 49 box 602, 3000, Leuven, Belgium., Hamed MB; VIB-KU Leuven Center for Brain & Disease Research, Herestraat 49 box 602, 3000, Leuven, Belgium.; Department of Neurosciences, Leuven Brain Institute, KU Leuven, Herestraat 49 box 602, 3000, Leuven, Belgium., Lismont S; VIB-KU Leuven Center for Brain & Disease Research, Herestraat 49 box 602, 3000, Leuven, Belgium.; Department of Neurosciences, Leuven Brain Institute, KU Leuven, Herestraat 49 box 602, 3000, Leuven, Belgium., Chávez-Gutiérrez L; VIB-KU Leuven Center for Brain & Disease Research, Herestraat 49 box 602, 3000, Leuven, Belgium. Lucia.ChavezGutierrez@kuleuven.be.; Department of Neurosciences, Leuven Brain Institute, KU Leuven, Herestraat 49 box 602, 3000, Leuven, Belgium. Lucia.ChavezGutierrez@kuleuven.be., Efremov RG; Center for Structural Biology, VIB, Brussels, Belgium. Rouslan.Efremov@vub.be.; Structural Biology Brussels, Department of Bioengineering Sciences, Vrije Universiteit Brussel, Brussels, Belgium. Rouslan.Efremov@vub.be.
Publikováno v: Nature communications [Nat Commun] 2024 May 27; Vol. 15 (1), pp. 4479. Date of Electronic Publication: 2024 May 27.
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4
Akademický článek
APP substrate ectodomain defines amyloid-β peptide length by restraining γ-secretase processivity and facilitating product release.
Autor: Koch M; VIB/KU Leuven, VIB-KU Leuven Center for Brain and Disease Research, Leuven, Belgium., Enzlein T; VIB/KU Leuven, VIB-KU Leuven Center for Brain and Disease Research, Leuven, Belgium.; Center for Mass Spectrometry and Optical Spectroscopy (CeMOS), Mannheim University of Applied Sciences, Mannheim, Germany., Chen SY; Physics Department and Center of Functional Protein Assemblies, Technical University of Munich, Garching, Germany., Petit D; VIB/KU Leuven, VIB-KU Leuven Center for Brain and Disease Research, Leuven, Belgium., Lismont S; VIB/KU Leuven, VIB-KU Leuven Center for Brain and Disease Research, Leuven, Belgium., Zacharias M; Physics Department and Center of Functional Protein Assemblies, Technical University of Munich, Garching, Germany., Hopf C; Center for Mass Spectrometry and Optical Spectroscopy (CeMOS), Mannheim University of Applied Sciences, Mannheim, Germany.; Mannheim Center for Translational Neuroscience (MCTN), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Medical Faculty, Heidelberg University, Heidelberg, Germany., Chávez-Gutiérrez L; VIB/KU Leuven, VIB-KU Leuven Center for Brain and Disease Research, Leuven, Belgium.
Publikováno v: The EMBO journal [EMBO J] 2023 Dec 01; Vol. 42 (23), pp. e114372. Date of Electronic Publication: 2023 Oct 18.
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5
Akademický článek
Enzyme-substrate interface targeting by imidazole-based γ-secretase modulators activates γ-secretase and stabilizes its interaction with APP.
Autor: Petit D; VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium.; Department of Neurosciences, Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven, Leuven, Belgium., Hitzenberger M; Center for Functional Protein Assemblies, Theoretical Biophysics (T38), Technical University of Munich, Garching, Germany., Koch M; VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium.; Department of Neurosciences, Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven, Leuven, Belgium., Lismont S; VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium.; Department of Neurosciences, Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven, Leuven, Belgium., Zoltowska KM; VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium.; Department of Neurosciences, Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven, Leuven, Belgium., Enzlein T; VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium.; Department of Neurosciences, Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven, Leuven, Belgium.; Center for Mass Spectrometry and Optical Spectroscopy (CeMOS), Mannheim University of Applied Sciences, Mannheim, Germany., Hopf C; Center for Mass Spectrometry and Optical Spectroscopy (CeMOS), Mannheim University of Applied Sciences, Mannheim, Germany.; Medical Faculty, Heidelberg University, Heidelberg, Germany., Zacharias M; Center for Functional Protein Assemblies, Theoretical Biophysics (T38), Technical University of Munich, Garching, Germany., Chávez-Gutiérrez L; VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium.; Department of Neurosciences, Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven, Leuven, Belgium.
Publikováno v: The EMBO journal [EMBO J] 2022 Nov 02; Vol. 41 (21), pp. e111084. Date of Electronic Publication: 2022 Sep 19.
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7
Akademický článek
Glutamate Transporter 1 as a Novel Negative Regulator of Amyloid β.
Autor: Sinha, Priyanka1 (AUTHOR) psinha4@mgh.harvard.edu, Turchyna, Yuliia1 (AUTHOR), Mitchell, Shane Patrick Clancy1 (AUTHOR), Sadek, Michael1 (AUTHOR), Armagan, Gokce1 (AUTHOR), Perrin, Florian1 (AUTHOR), Maesako, Masato1 (AUTHOR), Berezovska, Oksana1 (AUTHOR) psinha4@mgh.harvard.edu
Publikováno v: Cells (2073-4409). Oct2024, Vol. 13 Issue 19, p1600. 13p.
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8
Akademický článek
Melatonin Supplementation Alleviates Impaired Spatial Memory by Influencing Aβ 1-42 Metabolism via γ-Secretase in the icvAβ 1-42 Rat Model with Pinealectomy.
Autor: Georgieva, Irina1 (AUTHOR) igeorgieva@biomed.bas.bg, Tchekalarova, Jana2 (AUTHOR) janetchekalarova@gmail.com, Nenchovska, Zlatina2 (AUTHOR) zuzania@abv.bg, Kortenska, Lidia2 (AUTHOR) lkortenska@abv.bg, Tzoneva, Rumiana1 (AUTHOR) tzoneva@bio21.bas.bg
Publikováno v: International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 19, p10294. 12p.
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9
Akademický článek
Alzheimer's Disease Pathology and Assistive Nanotheranostic Approaches for Its Therapeutic Interventions.
Autor: Dey, Anuvab1 (AUTHOR) anuvab2000dey@gmail.com, Ghosh, Subhrojyoti2 (AUTHOR) subhrojyotighosh8@gmail.com, Rajendran, Ramya Lakshmi3 (AUTHOR) ramyag@knu.ac.kr, Bhuniya, Tiyasa4 (AUTHOR) tiyasa28082000@gmail.com, Das, Purbasha5 (AUTHOR) purbasha.mantai@gmail.com, Bhattacharjee, Bidyabati6 (AUTHOR) bidyabatibhattacharjee@gmail.com, Das, Sagnik7 (AUTHOR) sagnikd525@gmail.com, Mahajan, Atharva Anand8 (AUTHOR), Samant, Anushka9 (AUTHOR) anushkas2709@gmail.com, Krishnan, Anand10 (AUTHOR) krishnana1@ufs.ac.za, Ahn, Byeong-Cheol3,11,12 (AUTHOR) abc2000@knu.ac.kr, Gangadaran, Prakash3,12 (AUTHOR) abc2000@knu.ac.kr
Publikováno v: International Journal of Molecular Sciences. Sep2024, Vol. 25 Issue 17, p9690. 37p.
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10
Qualitative changes in human ?-secretase underlie familial Alzheimer's disease
Autor: Szaruga M., Veugelen S., Benurwar M., Lismont S., Sepulveda-Falla D., Lleo A., Ryan N.S., Lashley T., Fox N.C., Murayama S., Gijsen H., De Strooper B., Chávez-Gutiérrez L.
Publikováno v: JOURNAL OF EXPERIMENTAL MEDICINE
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Presenilin (PSEN) pathogenic mutations cause familial Alzheimer's disease (AD [FAD]) in an autosomal-dominant manner. The extent to which the healthy and diseased alleles influence each other to cause neurodegeneration remains unclear. In this study,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::a66587be8fe5b39e883e89069d8e5864
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=10396
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