Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Lisi Cai"'
Publikováno v:
Journal of Ovarian Research, Vol 12, Iss 1, Pp 1-8 (2019)
Abstract Aims This study was designed to evaluate the protective effects of AMPKα and SIRT1 on insulin resistance in PCOS rats, and to illuminate the underlying mechanisms. Methods An in vitro PCOS model was established by DHEA (6 mg/(100 g•d)), a
Externí odkaz:
https://doaj.org/article/70a029207b0d4ff5bcf5a85c6acd300d
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0177426 (2017)
PURPOSE:To explore the effects of conservative surgery for endometriomas on ovarian responsiveness during assisted reproductive technology (ART) and provide reproductive and gynecological doctors with a more reliable reference program for the treatme
Externí odkaz:
https://doaj.org/article/d103978ebb594aa8b9f0ef8ab6338503
Publikováno v:
Journal of Ovarian Research, Vol 12, Iss 1, Pp 1-8 (2019)
Journal of Ovarian Research
Journal of Ovarian Research
Aims This study was designed to evaluate the protective effects of AMPKα and SIRT1 on insulin resistance in PCOS rats, and to illuminate the underlying mechanisms. Methods An in vitro PCOS model was established by DHEA (6 mg/(100 g•d)), and the ra
Publikováno v:
Journal of Investigative Medicine. 67:729-735
The purpose of this study was to examine the relations of hormonal contraceptives and infertility drugs with the risk of venous thromboembolism (VTE), deep vein thrombosis (DVT), pulmonary embolism (PE), ischemic stroke, and cardiovascular disease. T
Exenatide can contribute to the therapeutic effect for PCOS patients in restoring menstrual cycles. To exploring endometrial tissue change in PCOS rats and the effects of exenatide on endometrial tissue, we carried out in vivo study of PCOS rat model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::def0f24c6d5c99ad033dbe9e9aa6bf21
https://doi.org/10.21203/rs.3.rs-28388/v1
https://doi.org/10.21203/rs.3.rs-28388/v1
Publikováno v:
Open Journal of Endocrine and Metabolic Diseases. :71-80
Objective: To investigate the relationship between AMPKα, PGCα, insulin resistance and reproductive function in PCOS mice and to find out the molecular mechanisms and potential therapeutic molecular targets of pathogenesis of PCOS. Methods: The PCO
Publikováno v:
Clinics
Clinics, Volume: 73, Article number: e364, Published: 09 AUG 2018
Clinics, Vol 73, Iss 0 (2018)
Clinics, Volume: 73, Article number: e364, Published: 09 AUG 2018
Clinics, Vol 73, Iss 0 (2018)
OBJECTIVES: Our purpose was to examine the associations of female genital infections and certain comorbidities with infertility. METHODS: The Taiwan National Health Research Database was searched for women with a new diagnosis of infertility between
Publikováno v:
Biochemical and biophysical research communications. 494(3-4)
In order to preliminarily explore the correlation between the AMPKα-SIRT1 pathway and insulin resistance and reproductive function in PCOS mice and find the pathogenesis molecular mechanism and potential therapeutic target of PCOS, we carried out in
Autor:
Shuangying Liu, Xiaotian Zhu, Angela Toms, Yongjin Xu, David C. Dalgarno, Rory Dodd, Lois Parillon, Yihan Wang, Scott Wardwell, Tim Clackson, Jiwei Qi, Anna Kohlmann, Yaoyu Ning, Hyun Gyung Jang, Xiaohui Lu, Lisi Cai, Qurish K. Mohemmad, Rongsong Xu, Dong Zou, Sen Zhang, William C. Shakespeare, Timothy A. Dwight, Narayana I. Narasimhan, Qihong Xu, Rana Anjum, Lauren Moran, Tianjun Zhou, Frank Wang, Mathew Thomas, Wei-Sheng Huang, Jeffrey A. Keats, Feng Li, Jan Romero, Victor M. Rivera
Publikováno v:
Journal of medicinal chemistry. 59(10)
In the treatment of echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase positive (ALK+) non-small-cell lung cancer (NSCLC), secondary mutations within the ALK kinase domain have emerged as a major resistance mechanism t
Autor:
Xiaotian Zhu, Dong Zou, Chester A. Metcalf, Raji Sundaramoorthi, Frank Wang, Feng Li, Jan Romero, John Iuliucci, Lois Commodore, Shuangying Liu, Wei-Sheng Huang, Lisi Cai, Qihong Xu, Jeff Keats, Tim Clackson, David C. Dalgarno, Joseph Snodgrass, Jiwei Qi, Yihan Wang, Victor M. Rivera, Mathew Thomas, Ingrid Chen, Tianjun Zhou, Yaoyu Ning, David Wen, Tomi K. Sawyer, Karin Russian, William C. Shakespeare, Marc I Broudy, Scott Wardwell
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:3743-3748
Ponatinib (AP24534) was previously identified as a pan-BCR-ABL inhibitor that potently inhibits the T315I gatekeeper mutant, and has advanced into clinical development for the treatment of refractory or resistant CML. In this study, we explored a nov