Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Lishuang Shen"'
Autor:
Elyssa Y. Wong, Liya Xu, Lishuang Shen, Mary E. Kim, Ashley Polski, Rishvanth K. Prabakar, Rachana Shah, Rima Jubran, Jonathan W. Kim, Jaclyn A. Biegel, Xiaowu Gai, Peter Kuhn, James Hicks, Jesse L. Berry
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-6 (2021)
Abstract Germline alterations in the RB1 tumor suppressor gene predispose patients to develop retinoblastoma (RB) in both eyes. While similar treatment is given for each eye, there is often a variable therapeutic response between the eyes. Herein, we
Externí odkaz:
https://doaj.org/article/cba62b9753aa46e6a2d5607deeabe06c
Autor:
Kathrine McAulay, Audrey N. Schuetz, Kathy Fauntleroy, Lishuang Shen, Yves-Mary Merveille, Alexandra Deroncelay, Nicolynn Cole, Daniel W. Fitzgerald, Oksana Ocheretina
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 25, Iss , Pp 60-65 (2021)
Objectives: Pseudomonas aeruginosa is a leading cause of opportunistic infections worldwide, particularly in healthcare settings, and frequently demonstrates resistance to commonly prescribed antimicrobials. Carbapenem resistance is prevalent worldwi
Externí odkaz:
https://doaj.org/article/afe0a7422bd646dd99a55bf131f59b1e
Autor:
Lishuang Shen, Jennifer Dien Bard, Timothy J. Triche, Alexander R. Judkins, Jaclyn A. Biegel, Xiaowu Gai
Publikováno v:
Emerging Microbes and Infections, Vol 10, Iss 1, Pp 885-893 (2021)
Mutations in the SARS-CoV-2 Membrane (M) gene are relatively uncommon. The M gene encodes the most abundant viral structural protein, and is implicated in multiple viral functions, including initial attachment to the host cell via heparin sulphate pr
Externí odkaz:
https://doaj.org/article/36225cc591ed41b89d2c56eb4a2cafd2
Autor:
Lishuang Shen, Jennifer Dien Bard, Timothy J. Triche, Alexander R. Judkins, Jaclyn A. Biegel, Xiaowu Gai
Publikováno v:
Emerging Microbes and Infections, Vol 10, Iss 1, Pp 1293-1299 (2021)
The SARS-CoV-2 B.1.1.7 lineage is highly infectious and as of April 2021 accounted for 92% of COVID-19 cases in Europe and 59% of COVID-19 cases in the U.S. It is defined by the N501Y mutation in the receptor-binding domain (RBD) of the Spike (S) pro
Externí odkaz:
https://doaj.org/article/f8aa19448b194282a64ae08f50d5999a
Autor:
Thao T. Truong, Alex Ryutov, Utsav Pandey, Rebecca Yee, Lior Goldberg, Deepa Bhojwani, Paibel Aguayo-Hiraldo, Benjamin A. Pinsky, Andrew Pekosz, Lishuang Shen, Scott D. Boyd, Oliver F. Wirz, Katharina Röltgen, Moiz Bootwalla, Dennis T. Maglinte, Dejerianne Ostrow, David Ruble, Jennifer H. Han, Jaclyn A. Biegel, Maggie Li, ChunHong Huang, Malaya K. Sahoo, Pia S. Pannaraj, Maurice O'Gorman, Alexander R. Judkins, Xiaowu Gai, Jennifer Dien Bard
Publikováno v:
EBioMedicine, Vol 67, Iss , Pp 103355- (2021)
Background: There is increasing concern that persistent infection of SARS-CoV-2 within immunocompromised hosts could serve as a reservoir for mutation accumulation and subsequent emergence of novel strains with the potential to evade immune responses
Externí odkaz:
https://doaj.org/article/42209873b5b849b2806a3d10b8822b27
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Genomic analysis of SARS-CoV-2 sequences is crucial in determining the effectiveness of prudent safer at home measures in the United States (US). By haplotype analysis of 6,356 US isolates, we identified a pattern of strongly localized outbreaks at t
Externí odkaz:
https://doaj.org/article/8bc3c67240da4c278b62c7403755aa51
Autor:
Margaret A Gustafson, Elizabeth M McCormick, Lalith Perera, Matthew J Longley, Renkui Bai, Jianping Kong, Matthew Dulik, Lishuang Shen, Amy C Goldstein, Shana E McCormack, Benjamin L Laskin, Bart P Leroy, Xilma R Ortiz-Gonzalez, Meredith G Ellington, William C Copeland, Marni J Falk
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0221829 (2019)
Mitochondrial DNA (mtDNA) genome integrity is essential for proper mitochondrial respiratory chain function to generate cellular energy. Nuclear genes encode several proteins that function at the mtDNA replication fork, including mitochondrial single
Externí odkaz:
https://doaj.org/article/63b1a4fb63464668996acd615bcb408a
Autor:
Liya Xu, Mary E. Kim, Ashley Polski, Rishvanth K. Prabakar, Lishuang Shen, Chen-Ching Peng, Mark W. Reid, Patricia Chévez-Barrios, Jonathan W. Kim, Rachana Shah, Rima Jubran, Peter Kuhn, David Cobrinik, Jaclyn A. Biegel, Xiaowu Gai, James Hicks, Jesse L. Berry
Publikováno v:
Cancers, Vol 13, Iss 6, p 1282 (2021)
Because direct tumor biopsy is prohibited for retinoblastoma (RB), eye-specific molecular biomarkers are not used in clinical practice for RB. Recently, we demonstrated that the aqueous humor (AH) is a rich liquid biopsy source of cell-free tumor DNA
Externí odkaz:
https://doaj.org/article/0c7521c9e71e4c88b71af9d0ef161318
Autor:
Samaneh Davoudi, Daniel Navarro-Gomez, Lishuang Shen, Cindy Ung, Aiai Ren, Lynn Sullivan, Mindy Kwong, Maria Janessian, Jason Comander, Xiaowu Gai, Ann-Marie Lobo, George N. Papaliodis, Lucia Sobrin
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 3, Iss C, Pp 39-42 (2016)
Purpose: Identifying genetic risk factors for developing sarcoidosis-associated uveitis could provide insights into its pathogenesis which is poorly understood. We determine if variants in NOD2 confer an increased risk of developing uveitis in adults
Externí odkaz:
https://doaj.org/article/b340593f461049e39bf30839f2284ac3
Autor:
Oksana Ocheretina, Lishuang Shen, Vincent E Escuyer, Marie-Marcelle Mabou, Gertrude Royal-Mardi, Sean E Collins, Jean W Pape, Daniel W Fitzgerald
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129207 (2015)
The World Health Organization recommends diagnosing Multidrug-Resistant Tuberculosis (MDR-TB) in high burden countries by detection of mutations in Rifampin (RIF) Resistance Determining Region of Mycobacterium tuberculosis rpoB gene with rapid molecu
Externí odkaz:
https://doaj.org/article/255b882bdd1948c7a8d41dabd9ad7836