Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Lishuang Qi"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Hypertension is a disease associated with epigenetic aging. However, the pathogenic mechanism underlying this relationship remains unclear. We aimed to characterize the shared genetic architecture of hypertension and epigenetic aging, and id
Externí odkaz:
https://doaj.org/article/4c486fdbeb674321806a1fd1b315a4ad
Autor:
Lei Wang, Lishuang Qi, Xiaoyi Huang, Xiao Feng, Junqing Gan, Juxuan Zhang, Yuhui Xi, Shuai Zhang, Qingwei Meng
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e33454- (2024)
Small cell lung cancer (SCLC) is a fatal tumor type that is prone to drug resistance. In our previous study, we showed that human rhomboid-5 homolog-1 (RHBDF1) was differentially expressed in 5 intrinsic cisplatin-resistant SCLC tissues compared with
Externí odkaz:
https://doaj.org/article/b4edab610f974e6ab6b9d77e15401380
Autor:
Bo Chen, Pengfei Li, Mingyue Liu, Kaidong Liu, Min Zou, Yiding Geng, Shuping Zhuang, Huanhuan Xu, Linzhu Wang, Tingting Chen, Yawei Li, Zhangxiang Zhao, Lishuang Qi, Yunyan Gu
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-16 (2022)
Abstract Background Diverse drug vulnerabilities owing to the Chromatin regulators (CRs) genetic interaction across various cancers, but the identification of CRs genetic interaction remains challenging. Methods In order to provide a global view of t
Externí odkaz:
https://doaj.org/article/393dfb786f974d46811c31e5b9ef314e
Autor:
Xin Li, Lefan Tang, Jiaxing Deng, Xiuying Qi, Juxuan Zhang, Haitao Qi, Mengyue Li, Yixin Liu, Wenyuan Zhao, Yunyan Gu, Lishuang Qi, Xia Li
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Transcriptomic analysis from lung adenocarcinoma identified an 11-gene signature that could classify metabolic reprogramming phenotypes in patients.
Externí odkaz:
https://doaj.org/article/54ab4430b0cd46a8850a8189ba24408b
Autor:
Juxuan Zhang, Jiaxing Deng, Xiao Feng, Yilong Tan, Xin Li, Yixin Liu, Mengyue Li, Haitao Qi, Lefan Tang, Qingwei Meng, Haidan Yan, Lishuang Qi
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Background: Lung cancer is a complex disease composed of neuroendocrine (NE) and non-NE tumors. Accurate diagnosis of lung cancer is essential in guiding therapeutic management. Several transcriptional signatures have been reported to distinguish bet
Externí odkaz:
https://doaj.org/article/69490701a4a548b481ee1444d95f1554
Autor:
Yixin Liu, Haitao Qi, Chunni Wang, Jiaxing Deng, Yilong Tan, Lin Lin, Zhirou Cui, Jin Li, Lishuang Qi
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundTo identify a computed tomography (CT) derived radiomic signature for the options of concurrent chemo-radiotherapy (CCR) in patients with non-small cell lung cancer (NSCLC).MethodsA total of 226 patients with NSCLC receiving CCR were enroll
Externí odkaz:
https://doaj.org/article/a54b427e8782455ba8a3ba8fee680a90
Autor:
Qi Dong, Mingyue Liu, Bo Chen, Zhangxiang Zhao, Tingting Chen, Chengyu Wang, Shuping Zhuang, Yawei Li, Yuquan Wang, Liqiang Ai, Yaoyao Liu, Haihai Liang, Lishuang Qi, Yunyan Gu
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 4435-4446 (2021)
Poly (ADPribose) polymerase inhibitors (PARPis) are clinically approved drugs designed according to the concept of synthetic lethality (SL) interaction. It is crucial to expand the scale of patients who can benefit from PARPis, and overcome drug resi
Externí odkaz:
https://doaj.org/article/cf34724db82342edadb3c5f7ca37ed93
Autor:
Ying Li, Wenbin Jiang, Tianhao Li, Mengyue Li, Xin Li, Zheyang Zhang, Sainan Zhang, Yixin Liu, Wenyuan Zhao, Yunyan Gu, Lishuang Qi, Lu Ao, Zheng Guo
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-12 (2020)
Abstract Background Immune checkpoint inhibitors are effective in some cases of lung adenocarcinoma (LUAD). Whole-exome sequencing has revealed that the tumour mutation burden (TMB) is associated with clinical benefits among patients from immune chec
Externí odkaz:
https://doaj.org/article/e782930299484096a5687274dd19368f
Autor:
Xin Li, Gengen Shi, Qingsong Chu, Wenbin Jiang, Yixin Liu, Sainan Zhang, Zheyang Zhang, Zixin Wei, Fei He, Zheng Guo, Lishuang Qi
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-16 (2019)
Abstract Background Targeted therapy for non-small cell lung cancer is histology dependent. However, histological classification by routine pathological assessment with hematoxylin-eosin staining and immunostaining for poorly differentiated tumors, p
Externí odkaz:
https://doaj.org/article/10413f4adcb24ec1ae4ee1a30f75773e
Autor:
Yelin Fu, Lishuang Qi, Wenbing Guo, Liangliang Jin, Kai Song, Tianyi You, Shuobo Zhang, Yunyan Gu, Wenyuan Zhao, Zheng Guo
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-9 (2019)
Abstract Background Microsatellite instability (MSI) accounts for about 15% of colorectal cancer and is associated with prognosis. Today, MSI is usually detected by polymerase chain reaction amplification of specific microsatellite markers. However,
Externí odkaz:
https://doaj.org/article/5acf1d48a4b64d3182ce6d1895ff9d43