Zobrazeno 1 - 10
of 234
pro vyhledávání: '"Lishomwa C. Ndhlovu"'
Autor:
Thomas A. Premeaux, Scott Bowler, Courtney M. Friday, Carlee B. Moser, Martin Hoenigl, Michael M. Lederman, Alan L. Landay, Sara Gianella, Lishomwa C. Ndhlovu
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109945- (2024)
Summary: Despite the success of antiretroviral therapy (ART), individuals with HIV remain at risk for experiencing non-AIDS adverse events (NAEs), including cardiovascular complications and malignancy. Several surrogate immune biomarkers in blood hav
Externí odkaz:
https://doaj.org/article/d190aea2d2ba4ccb8dda73df9260d004
Autor:
Erika G. Marques de Menezes, Scott A. Bowler, Cecilia M. Shikuma, Lishomwa C. Ndhlovu, Philip J. Norris
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundAlthough effective antiretroviral therapy (ART) has improved the life expectancy of people with HIV (PWH), the prevalence of milder forms of HIV-associated neurocognitive disorders (HAND) persist, and it is associated with systemic and neur
Externí odkaz:
https://doaj.org/article/6de4734169194ec2ae940746b4ace112
Autor:
Wanwisa Promsote, Kesara Chumpolkulwong, Thomas Musich, Michael J. Corley, Lishomwa C. Ndhlovu, Jumpol Sopanaporn, Dutsadee Inthawong, Panupat Nadee, Decha Silsorn, Siwikorn Sirisrisopa, Sakda Wongsawanonkul, Matthew S. Parsons, Jessica Cowden, Rawiwan Imerbsin, Luis Lugo-Roman, Sandhya Vasan, Denise C. Hsu
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 33, Iss , Pp 100683- (2023)
Sleep deprivation in humans is associated with both cognitive impairment and immune dysregulation. An animal model of neuropathogenesis may provide insight to understand the effects of sleep deprivation on the brain. Human neurocognition is more clos
Externí odkaz:
https://doaj.org/article/bbfe19eb9540490e88d63258dcdf6ec0
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Multiple cellular HIV reservoirs in diverse anatomical sites can undergo clonal expansion and persist for years despite suppressive antiretroviral therapy, posing a major barrier toward an HIV cure. Commonly adopted assays to assess HIV rese
Externí odkaz:
https://doaj.org/article/37bec579483a48a6aa137b8240892270
Autor:
Benderli Christine Nana, Livo Forgu Esemu, Michael Ebangha Besong, Derrick Hyacinthe Nyasse Atchombat, Kazuhiro Ogai, Thérèse M. Patricia Sobgui, Chris Marco Mbianda Nana, Reine Medouen Ndeumou Seumko’o, Honoré Awanakan, Gabriel Loni Ekali, Rose Gana Fomban Leke, Shigefumi Okamoto, Lishomwa C. Ndhlovu, Rosette Megnekou
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundHuman Herpesvirus-8 (HHV-8) is the etiologic agent of Kaposi’s sarcoma (KS), a multicentric angio-proliferative cancer commonly associated with Human Immunodeficiency Virus (HIV) infection. KS pathogenesis is a multifactorial condition hi
Externí odkaz:
https://doaj.org/article/b4416675fe41442483012332fa4872d0
Autor:
Alexandra Schuetz, Michael J. Corley, Carlo Sacdalan, Yuwadee Phuang-Ngern, Thitiyanun Nakpor, Tanyaporn Wansom, Philip K. Ehrenberg, Somchai Sriplienchan, Rasmi Thomas, Nisakorn Ratnaratorn, Suchada Sukhumvittaya, Nipattra Tragonlugsana, Bonnie M. Slike, Siriwat Akapirat, Suteeraporn Pinyakorn, Rungsun Rerknimitr, Alina P.S. Pang, Eugène Kroon, Nipat Teeratakulpisan, Shelly J. Krebs, Nittaya Phanuphak, Lishomwa C. Ndhlovu, Sandhya Vasan, on behalf of the RV304/SEARCH013 Study Team
Publikováno v:
JCI Insight, Vol 8, Iss 16 (2023)
Transgender women (TGW) are disproportionally affected by HIV infection, with a global estimated prevalence of 19.9%, often attributed to behavioral risk factors, with less known about biological factors. We evaluated potential biological risk factor
Externí odkaz:
https://doaj.org/article/5c07b50505a5416eb65e1350d531d2ea
Autor:
Julie Joseph, Thomas A. Premeaux, Daniel O. Pinto, Abhishek Rao, Shrobona Guha, Amanda R. Panfil, Alison J. Carey, Lishomwa C. Ndhlovu, Elke S. Bergmann‐Leitner, Pooja Jain
Publikováno v:
Journal of Extracellular Biology, Vol 2, Iss 7, Pp n/a-n/a (2023)
Abstract HTLV‐I‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic, progressive, neuroinflammatory demyelinating condition of the spinal cord. We have previously shown that aberrant expression and activity of immune checkpo
Externí odkaz:
https://doaj.org/article/afc11930d2954a59b80a6aaff0b265a4
Autor:
Scott Bowler, Georgios Papoutsoglou, Aristides Karanikas, Ioannis Tsamardinos, Michael J. Corley, Lishomwa C. Ndhlovu
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Since the onset of the COVID-19 pandemic, increasing cases with variable outcomes continue globally because of variants and despite vaccines and therapies. There is a need to identify at-risk individuals early that would benefit from timely
Externí odkaz:
https://doaj.org/article/b5d98b8fb0da490a9f7efec0cabcabc8
Autor:
Danielle E. Lyons, Priti Kumar, Nadia R. Roan, Patricia A. Defechereux, Cedric Feschotte, Ulrike C. Lange, Niren Murthy, Pauline Sameshima, Eric Verdin, Julie A. Ake, Matthew S. Parsons, Avindra Nath, Sara Gianella, Davey M. Smith, Esper G. Kallas, Thomas J. Villa, Richard Strange, Betty Mwesigwa, Robert L. Furler O’Brien, Douglas F. Nixon, Lishomwa C. Ndhlovu, Susana T. Valente, Melanie Ott
Publikováno v:
Viruses, Vol 15, Iss 11, p 2171 (2023)
Despite remarkable progress, a cure for HIV-1 infection remains elusive. Rebound competent latent and transcriptionally active reservoir cells persevere despite antiretroviral therapy and rekindle infection due to inefficient proviral silencing. We p
Externí odkaz:
https://doaj.org/article/e4df173514554fe9824778fa69c18045
Autor:
Denise C. Hsu, Kesara Chumpolkulwong, Michael J. Corley, Taweewun Hunsawong, Dutsadee Inthawong, Alexandra Schuetz, Rawiwan Imerbsin, Decha Silsorn, Panupat Nadee, Jumpol Sopanaporn, Yuwadee Phuang-Ngern, Chonticha Klungthong, Matthew Reed, Stefan Fernandez, Lishomwa C. Ndhlovu, Robert Paul, Luis Lugo-Roman, Nelson L. Michael, Kayvon Modjarrad, Sandhya Vasan
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-13 (2022)
Abstract Background Zika virus (ZIKV) is a mosquito-transmitted flavivirus that affects many regions of the world. Infection, in utero, causes microcephaly and later developmental and neurologic impairments. The impact of ZIKV infection on neurocogni
Externí odkaz:
https://doaj.org/article/e9647a938c85447f9d074e858696630c