Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Lisheng Zhuo"'
Autor:
Jiarui Zhang, Yoshihiro Nishida, Hiroshi Koike, Lisheng Zhuo, Kan Ito, Kunihiro Ikuta, Tomohisa Sakai, Shiro Imagama
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12422 (2023)
This study aimed to clarify the effects of ipriflavone, which effectively reduces KIAA1199 activity, on osteoarthritis (OA) development and progression in an in vivo OA mouse model. The OA model mice were divided into the ipriflavone (200 mg/kg/day)
Externí odkaz:
https://doaj.org/article/b578f9ca63cc4ee99b30cb0962c1dd71
Autor:
Hiroshi Koike, Yoshihiro Nishida, Tamayuki Shinomura, Bisei Ohkawara, Kinji Ohno, Lisheng Zhuo, Koji Kimata, Takahiro Ushida, Shiro Imagama
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 8, p 4089 (2022)
KIAA1199 has a strong hyaluronidase activity in inflammatory arthritis. This study aimed to identify a drug that could reduce KIAA1199 activity and clarify its effects on inflammatory arthritis. Rat chondrosarcoma (RCS) cells were strongly stained wi
Externí odkaz:
https://doaj.org/article/6d42f0d3a1f44c6abf836227c3f32564
Autor:
Yoshitoshi Higuchi, Yoshihiro Nishida, Eiji Kozawa, Lisheng Zhuo, Eisuke Arai, Shunsuke Hamada, Daigo Morita, Kunihiro Ikuta, Koji Kimata, Takahiro Ushida, Naoki Ishiguro
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The catabolism of hyaluronan in articular cartilage remains unclear. The aims of this study were to investigate the effects of hyaluronidase 2 (Hyal2) knockdown in articular cartilage on the development of osteoarthritis (OA) using genetic m
Externí odkaz:
https://doaj.org/article/05e159b5fcb542dc9216288f24301a65
Autor:
Jiarui Zhang, Yoshihiro Nishida, Hiroshi Koike, Kan Ito, Lisheng Zhuo, Kazuki Nishida, Koji Kimata, Kunihiro Ikuta, Tomohisa Sakai, Hiroshi Urakawa, Taisuke Seki, Shiro Imagama
Publikováno v:
Journal of Orthopaedic Research. 41:307-315
Hyaluronan (HA) plays crucial roles in the maintenance of high-quality cartilage extracellular matrix. Several studies have reported the HA in synovial fluid in patients with osteoarthritis (OA), but few have described the changes of HA in articular
Autor:
Yuqiang Li, Iida, Hiroki, Kimata, Koji, Lisheng Zhuo, Ota, Akinobu, Kimura, Shinya, Xiaojian Yin, Deie, Masataka, Ushida, Takahiro
Supplemental material, MPX892389 Supplemental Material3 for Establishment of a mouse model for injury-induced scar formation and the accompanying chronic pain: Comprehensive microarray analysis of molecular expressions in fibrosis and hyperalgesia by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72bcbfe73269a75d9eee5a77670d3865
Autor:
Naoki Ishiguro, Hongyan Ding, Koji Kimata, Yoshihiro Nishida, Qiang Dong, Yanan Xie, Lisheng Zhuo
Publikováno v:
Journal of Zhejiang University-SCIENCE B. 20:428-436
Hyaluronan is a widely occurring extracellular matrix molecule, which is not only a supporting structural component, but also an active regulator of cellular functions. The chemophysical and biological properties of hyaluronan are greatly affected by
Autor:
Lisheng Zhuo, Koji Kimata, Yow-Pin Lim, Vandy P. Stober, Stavros Garantziotis, Steven M. Opal
Publikováno v:
Lung
PURPOSE: Vascular endothelial cells demonstrate severe injury in sepsis, and a reduction in endothelial inflammation would be beneficial. Inter-α-Inhibitor (IαI) is a family of abundant plasma proteins with anti-inflammatory properties and has been
Autor:
Hiromitsu Yabushita, Keita Iwasaki, Kouhei Kanyama, Yukihiko Obayashi, Lisheng Zhuo, Naoki Itano, Koji Kimata, Akihiko Wakatsuki
Publikováno v:
Obstetrics and Gynecology International, Vol 2011 (2011)
The role of hyaluronan (HA), serum-derived HA-associated protein (SHAP)-HA complex and hyaluronan synthase (HAS) in endometrial carcinomas was investigated. The relationship of metalloproteinase (MMP) and its inhibitor (TIMP) with HA and the SHAP-HA
Externí odkaz:
https://doaj.org/article/f0ee17a217574502a314b07becf56fee
Autor:
Yuqiang Li, Hiroki Iida, Koji Kimata, Lisheng Zhuo, Akinobu Ota, Shinya Kimura, Xiaojian Yin, Masataka Deie, Takahiro Ushida
Publikováno v:
Molecular Pain; 12/30/2019, Vol. 15, p1-36, 36p, 3 Diagrams, 11 Charts, 3 Graphs
Autor:
Lisheng Zhuo, Tamayuki Shinomura, Yoshihiro Nishida, Naoki Ishiguro, Kunihiro Ikuta, Eisuke Arai, Takahiro Ushida, Hiroshi Koike, Koji Kimata, Shunsuke Hamada
Publikováno v:
Journal of Orthopaedic Research®. 36:1573-1580
Hyaluronan (HA) has been shown to play crucial roles in the tumorigenicity of malignant tumors. Chondrosarcoma, particularly when low-grade, is characterized by the formation of an extracellular matrix (ECM) containing abundant HA, and its drug/radia