Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Lisha YING"'
Autor:
Qian Li, Tingting Feng, Jing Zhu, Chang Yu, Ying Yang, Qixun Chen, Dan Su, Xiaotian Zhang, Changbin Zhu, Rui Zhu, Tingting Lu, Liwei Xu, Lisha Ying, Canming Wang, Weiming Xu, Jinchao Wang, Minran Huang, Chenyang Xu, Jiaoyue Jin
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 8 (2024)
Background Neoadjuvant chemoimmunotherapy has a promising effect on locally advanced esophageal squamous cell carcinoma (ESCC). However, reliable biomarkers robustly predicting therapeutic response are still lacking.Methods Formalin-fixed and paraffi
Externí odkaz:
https://doaj.org/article/5175472c9774416ebbcc62faf1771cfc
Publikováno v:
Chinese Journal of Lung Cancer, Vol 27, Iss 1, Pp 65-72 (2024)
Granulocytic myeloid-derived suppressor cells (G-MDSCs) are one of the main subgroups of MDSCs, which are widely enriched in most cancers. It can inhibit the killing function of T-lymphocyte through the expression of arginase-1 (Arg-1) and reactive o
Externí odkaz:
https://doaj.org/article/8ab7968209464095a4ffd511380abb19
Publikováno v:
Chinese Journal of Lung Cancer, Vol 26, Iss 11, Pp 874-880 (2023)
Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) targeting EGFR are effective in EGFR mutation-positive non-small cell lung cancer (NSCLC) patients, but drug resistance is inevitable. With the application and expansion of indiv
Externí odkaz:
https://doaj.org/article/eb14d81ecb434782a872d100dc8d5b81
Autor:
Lisha Ying, Chunliu Zhang, Alexandre Reuben, Yiping Tian, Jiaoyue Jin, Canming Wang, Jing Bai, Xinyuan Liu, Jianfei Fang, Tingting Feng, Chenyang Xu, Rui Zhu, Minran Huang, Yingqi Lyu, Tingting Lu, Xiaodan Pan, Jianjun Zhang, Dan Su
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107732- (2023)
Summary: The immunogenomic features of tumor-adjacent lungs (TALs) in stage I lung squamous cell carcinoma (LUSC) are not clear. Multiomics analyses of tumor tissues and paired TALs from 59 stage I LUSC patients were performed. Compared to tumors, TA
Externí odkaz:
https://doaj.org/article/71ad2ab7c2534a0a9c8588b74fd27782
Autor:
Hitoshi Dejima, Xin Hu, Runzhe Chen, Jiexin Zhang, Junya Fujimoto, Edwin R. Parra, Cara Haymaker, Shawna M. Hubert, Dzifa Duose, Luisa M. Solis, Dan Su, Junya Fukuoka, Kazuhiro Tabata, Hoa H. N. Pham, Nicholas Mcgranahan, Baili Zhang, Jie Ye, Lisha Ying, Latasha Little, Curtis Gumbs, Chi-Wan Chow, Marcos Roberto Estecio, Myrna C. B. Godoy, Mara B. Antonoff, Boris Sepesi, Harvey I. Pass, Carmen Behrens, Jianhua Zhang, Ara A. Vaporciyan, John V. Heymach, Paul Scheet, J. Jack Lee, Jia Wu, P. Andrew Futreal, Alexandre Reuben, Humam Kadara, Ignacio I. Wistuba, Jianjun Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
The evolution of immune landscape in lung adenocarcinoma (ADC) is largely unknown. Here the authors use a cohort of resected invasive lung ADC and its precursors and show a gradual increase of immunosuppression and decrease of anti-tumor response ass
Externí odkaz:
https://doaj.org/article/90f6cd0b92e742178a0fc4cce008b8e0
Autor:
Xin Hu, Marcos R. Estecio, Runzhe Chen, Alexandre Reuben, Linghua Wang, Junya Fujimoto, Jian Carrot-Zhang, Nicholas McGranahan, Lisha Ying, Junya Fukuoka, Chi-Wan Chow, Hoa H. N. Pham, Myrna C. B. Godoy, Brett W. Carter, Carmen Behrens, Jianhua Zhang, Mara B. Antonoff, Boris Sepesi, Yue Lu, Harvey I. Pass, Humam Kadara, Paul Scheet, Ara A. Vaporciyan, John V. Heymach, Ignacio I. Wistuba, J. Jack Lee, P. Andrew Futreal, Dan Su, Jean-Pierre J. Issa, Jianjun Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
It is known that invasive lung adenocarcinomas evolve from pre-cancerous dysplastic lesions. In this study, the authors show that evolution of pre-cancerous lesions is accompanied by DNA methylation alterations, and that global hypomethylation correl
Externí odkaz:
https://doaj.org/article/031719f1a9f8488a91a5917acd62743f
Autor:
Dan Su, Dadong Zhang, Jiaoyue Jin, Lisha Ying, Miao Han, Kaiyan Chen, Bin Li, Junzhou Wu, Zhenghua Xie, Fanrong Zhang, Yihui Lin, Guoping Cheng, Jing-Yu Li, Minran Huang, Jinchao Wang, Kailai Wang, Jianjun Zhang, Fugen Li, Lei Xiong, Andrew Futreal, Weimin Mao
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Predicting the drug response of patients with cancer is crucial for implementing targeted therapy. Here, Su et al. make patient-derived cell lines and perform targeted sequencing and RNA-seq to identify CDKN2A/2B loss as a predictor of response to CD
Externí odkaz:
https://doaj.org/article/03e2472bfffe4d77bb873151b95d70ea
Autor:
Xin Hu, Junya Fujimoto, Lisha Ying, Junya Fukuoka, Kazuto Ashizawa, Wenyong Sun, Alexandre Reuben, Chi-Wan Chow, Nicholas McGranahan, Runzhe Chen, Jinlin Hu, Myrna C. Godoy, Kazuhiro Tabata, Kishio Kuroda, Lei Shi, Jun Li, Carmen Behrens, Edwin Roger Parra, Latasha D. Little, Curtis Gumbs, Xizeng Mao, Xingzhi Song, Samantha Tippen, Rebecca L. Thornton, Humam Kadara, Paul Scheet, Emily Roarty, Edwin Justin Ostrin, Xu Wang, Brett W. Carter, Mara B. Antonoff, Jianhua Zhang, Ara A. Vaporciyan, Harvey Pass, Stephen G. Swisher, John V. Heymach, J. Jack Lee, Ignacio I. Wistuba, Waun Ki Hong, P. Andrew Futreal, Dan Su, Jianjun Zhang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
There has been a drastic increase in detection of lung nodules, many of which are precancers, preinvasive, minimally invasive or sometimes invasive lung cancers. Here, Hu et al. perform multi-region exome sequencing to discern the evolutional traject
Externí odkaz:
https://doaj.org/article/6c98a1e227804a168c18ce27f945729f
Autor:
Fanrong Zhang, Lisha Ying, Jiaoyue Jin, Jianguo Feng, Kaiyan Chen, Minran Huang, Yingxue Wu, Herbert Yu, Dan Su
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-12 (2018)
Abstract Background Brain metastasis is an extremely serious sequela with a dismal prognosis in non-small cell lung cancer (NSCLC). The present study aimed to identify novel biomarkers and potential therapeutic targets for brain metastases of NSCLC.
Externí odkaz:
https://doaj.org/article/849f2be5d5734f68a218af731119c25f
Autor:
Dan Su, Dadong Zhang, Kaiyan Chen, Jing Lu, Junzhou Wu, Xinkai Cao, Lisha Ying, Qihuang Jin, Yizhou Ye, Zhenghua Xie, Lei Xiong, Weimin Mao, Fugen Li
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 36, Iss 1, Pp 1-12 (2017)
Abstract Background Next generation sequencing (NGS) is being increasingly applied for assisting cancer molecular diagnosis. However, it is still needed to validate NGS accuracy on detection of DNA alternations based on a large number of clinical sam
Externí odkaz:
https://doaj.org/article/fbb9ea38d80b4ae6b0bc4ba33c91ad79