Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Lisha Kuang"'
Autor:
Dan Song, Lisha Kuang, Lin Yang, Lei Wang, Hao Li, Xiu Li, Zhimin Zhu, Chaowei Shi, Haining Zhu, Weimin Gong
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Stress granules (SGs) are cytoplasmic biomolecular condensates containing proteins and RNAs in response to stress. Ras-GTPase–activating protein binding protein 1 (G3BP1) is a core SG protein. Caprin-1 and ubiquitin specific peptidase 10 (USP10) in
Autor:
Jozsef Gal, Edward J. Kasarskis, Haining Zhu, Alexandra Arenas, Jing M. Chen, Lisha Kuang, Kelly R. Barnett
Publikováno v:
Hum Mol Genet
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the preferential death of motor neurons. Approximately 10% of ALS cases are familial and 90% are sporadic. Fused in sarcoma (FUS) is a ubiquitously expressed RNA-bind
Publikováno v:
Hum Mol Genet
Human molecular genetics, vol 29, iss 4
Human molecular genetics, vol 29, iss 4
Frontotemporal dementia (FTD) is an early onset dementia characterized by progressive atrophy of the frontal and/or temporal lobes. FTD is highly heritable with mutations in progranulin accounting for 5–26% of cases in different populations. Progra
Publikováno v:
J Neurochem
Fused in sarcoma (FUS) is a ubiquitously expressed RNA/DNA-binding protein that plays different roles in the cell. FUS pathology has been reported in neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Mu
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Mutations in fused in sarcoma (FUS) contribute to a subset of familial amyotrophic lateral sclerosis (ALS). ALS-linked mutations cause a liquid–liquid phase separation of FUS protein, induce cytoplasmic inclusions in cells, and interfe
Autor:
Edward J. Kasarskis, Jozsef Gal, Deborah Taylor, Alexandra Arenas, Haining Zhu, Weiming Gong, Daret K. St. Clair, Lisha Kuang, Martin Brown, Marisa Kamelgarn
Publikováno v:
Neurology: Genetics
Objective:To describe the clinical features of a novel fused in sarcoma (FUS) mutation in a young adult female amyotrophic lateral sclerosis (ALS) patient with rapid progression of weakness and to experimentally validate the consequences of the P525R
Autor:
Arenas, Alexandra, Jing Chen, Lisha Kuang, Barnett, Kelly R., Kasarskis, Edward J., Gal, Jozsef, Haining Zhu
Publikováno v:
Human Molecular Genetics; Aug2020, Vol. 29 Issue 16, p2684-2697, 14p, 1 Diagram, 1 Chart, 5 Graphs
Autor:
Jing Chen, Marisa Kamelgarn, Alexandra Arenas, Haining Zhu, Lisha Kuang, Jianjun Zhai, Jozsef Gal
Publikováno v:
Biochimica et biophysica acta. 1862(10)
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease. Mutations in the Fused in Sarcoma/Translocated in Liposarcoma (FUS/TLS) gene cause a subset of familial ALS cases and are also implicated in sporadic ALS. FUS is typicall
Autor:
Lei Wang, Liping Yu, Bing Du, Zhongliang Zhou, Min Qian, Ziqiang Wang, Miao Wu, Honghui Han, Lisha Kuang
Publikováno v:
Molecular Cancer Research. 8:135-144
Hepatocellular carcinoma is one of the deadliest cancers in the world. In this study, a hepatocarcinoma-specific binding peptide, which could be used for drug delivery in targeting therapy, was obtained by in vivo phage display technology. After thre
Publikováno v:
Molecular and Biochemical Parasitology. 168:84-94
Two different classes of small nematode specific lipid-binding proteins, the nematode polyprotein allergens/antigens (NPAs) and the fatty acid- and retinol-binding (FAR) proteins, are secreted by helminth parasites. Until now, there was no evidence o