Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lisha Arora"'
Autor:
Ashish Joshi, Anuja Walimbe, Snehasis Sarkar, Lisha Arora, Gaganpreet Kaur, Prince Jhandai, Dhruba Chatterjee, Indranil Banerjee, Samrat Mukhopadhyay
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Physical properties of biomolecular condensates formed via phase separation of proteins and nucleic acids are associated with cell physiology and disease. Condensate properties can be regulated by several cellular factors including post-tran
Externí odkaz:
https://doaj.org/article/bd9e2122a54d4b0f9c79dae0a95edaa9
Autor:
Ashish Joshi, Anuja Walimbe, Anamika Avni, Sandeep K. Rai, Lisha Arora, Snehasis Sarkar, Samrat Mukhopadhyay
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Biomolecular condensates formed via phase separation of proteins and nucleic acids are thought to be associated with a wide range of cellular functions and dysfunctions. We dissect critical molecular events associated with phase separation o
Externí odkaz:
https://doaj.org/article/09f2454533aa4581934e09b5a5efd549
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
The authors show that prion protein and α-synuclein undergo phase separation through domain-specific electrostatic interactions. These complex coacervates possess electrostatic nanoclusters and can convert into multiphasic condensates and amyloids.
Externí odkaz:
https://doaj.org/article/5f9709f9d05a48a1856125feb3581324
Autor:
Ashish Joshi, Anuja Walimbe, Anamika Avni, Sandeep K. Rai, Lisha Arora, Snehasis Sarkar, Samrat Mukhopadhyay
Biomolecular condensates formed via phase separation of proteins and nucleic acids are thought to be associated with a wide range of cellular functions and dysfunctions. We dissect critical molecular events associated with phase separation of an intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1b2f247466402b7dc908fc4e9da9804
https://doi.org/10.1101/2023.05.23.541917
https://doi.org/10.1101/2023.05.23.541917
Autor:
Lisha Arora, Samrat Mukhopadhyay
Publikováno v:
The Journal of Physical Chemistry B. 126:5137-5139
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4d2fdb8846fc6206528e83e06b72ef6
https://doi.org/10.1021/acs.jpcb.2c04017
https://doi.org/10.1021/acs.jpcb.2c04017
Publikováno v:
Nature Communications. 13
Biomolecular condensates formed via liquid-liquid phase separation (LLPS) of proteins and nucleic acids are thought to govern critical cellular functions. These multicomponent assemblies provide dynamic hubs for competitive homotypic and heterotypic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95716f7e71a2df48f3c217e59d41646a
https://doi.org/10.1038/s41467-022-28797-5
https://doi.org/10.1038/s41467-022-28797-5
Publikováno v:
Journal of the American Chemical Society. 144(4)
Protein folding and dynamics are governed by an intricate interplay of thermal and viscosity-mediated effects. The solvent viscosity contributes to the frictional drag in protein dynamics. In addition to this viscosity-dependent effect, there is also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea564801bc231dac0c07e85b7b1c7b73
https://pubmed.ncbi.nlm.nih.gov/35068142
https://pubmed.ncbi.nlm.nih.gov/35068142
Publikováno v:
Biophysical Journal. 121:473a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf3d1d38a8c6a29937c35a7eb8a8433f
https://doi.org/10.1016/j.bpj.2021.11.420
https://doi.org/10.1016/j.bpj.2021.11.420