Výsledky vyhledávání - "Lisette Ungethüm"

Akademický článek

Molecular imaging of cell death in tumors. Increasing annexin A5 size reduces contribution of phosphatidylserine-targeting function to tumor uptake.

Autor: Lisette Ungethüm, Martijn Chatrou, Dennis Kusters, Leon Schurgers, Chris P Reutelingsperger

Publikováno v: PLoS ONE, Vol 9, Iss 5, p e96749 (2014)

OBJECTIVE: Annexin A5 is a phosphatidylserine binding protein that binds dying cells in vivo. Annexin A5 is a potential molecular imaging agent to determine efficacy of anti-cancer therapy in patients. Its rapid clearance from circulation limits tumo

Externí odkaz: https://doaj.org/article/4d40efdb47d64d87920a53357e92b364

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Factor Xa-driven thrombin generation in plasma: Dependency on the aminophospholipid density of membranes and inhibition by phospholipid-binding proteins

Autor: Theo Lindhout, Chris P. M. Reutelingsperger, Simone J.H. Wielders, Lisette Ungethüm, Edouard M. Bevers

Publikováno v: Thrombosis and Haemostasis. 98:1056-1062

SummaryPhosphatidylserine (PS) externalization of activated platelets plays a pivotal role in haemostasis and thrombosis. In the present study we have explored the relationship between the PS density of membranes and the rate of thrombin generation i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5036a130800fda0f4f75152b1087f701
https://doi.org/10.1160/th07-05-0322

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Engineered Annexin A5 Variants Have Impaired Cell Entry for Molecular Imaging of Apoptosis Using Pretargeting Strategies*

Autor: Gerry A. F. Nicolaes, Chris P. M. Reutelingsperger, Heidi Kenis, Svetla Stoilova-McPhie, Lisette Ungethüm, Ludovic Autin

Publikováno v: Journal of Biological Chemistry, 286(3), 1903-1910. American Society for Biochemistry and Molecular Biology, Inc.

Phosphatidylserine ( PS) on apoptotic cells is a target for diagnosis and therapy using annexin A5 (anxA5). Pretargeting is a strategy developed to improve signal to background ratio for molecular imaging and to minimize undesired side effects of pha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7f15d6bff1dc9a6913b1775e87ebae1
https://europepmc.org/articles/PMC3023486/

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Factor Xa-driven thrombin generation in plasma: dependency on the aminophospholipid density of membranes and inhibition by phospholipid-binding proteins

Autor: Simone J H, Wielders, Lisette, Ungethüm, Chris P M, Reutelingsperger, Edouard M, Bevers, Theo, Lindhout

Publikováno v: Thrombosis and haemostasis. 98(5)

Phosphatidylserine (PS) externalization of activated platelets plays a pivotal role in haemostasis and thrombosis. In the present study we have explored the relationship between the PS density of membranes and the rate of thrombin generation in plasm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::57a79c9db634026644186d50dfb01e41
https://pubmed.ncbi.nlm.nih.gov/18000611

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Molecular Imaging of Cell Death in Tumors. Increasing Annexin A5 Size Reduces Contribution of Phosphatidylserine-Targeting Function to Tumor Uptake

Autor: Chris P. M. Reutelingsperger, Martijn L. Chatrou, Leon J. Schurgers, Lisette Ungethüm, Dennis H. M. Kusters

Publikováno v: PLoS ONE
PLOS ONE, 9(5). Public Library of Science
PLoS ONE, Vol 9, Iss 5, p e96749 (2014)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e33f6e5cf07f9425c0fe029c69e202
https://doi.org/10.1371/journal.pone.0096749

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