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pro vyhledávání: '"Lisette B. W. Schroder"'
Autor:
Shane Whittaker, Kerrie L. McDonald, Robert W. Rapkins, Lisette B. W. Schroder, Sheri Nixdorf, Swapna Joshi, Ashleigh Lester, Kyoko Nozue, Toni Rose Jue, Mustafa Khasraw
Publikováno v:
Journal of Translational Medicine
The O 6 -methylguanine methyltransferase (MGMT) gene is frequently unmethylated in patients with glioblastoma (GBM), rendering them non-responsive to the standard treatment regime of surgery followed by concurrent radiotherapy (RT) and temozolomide.
Publikováno v:
Frontiers in Oncology, Vol 5 (2015)
Frontiers in Oncology
Frontiers in Oncology
Glioblastoma is aggressive, highly infiltrating, and the most frequent malignant form of brain cancer. With a median survival time of only 14.6 months, when treated with the standard of care, it is essential to find new therapeutic options. A specifi