Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Lisette, Leyton"'
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 4, Pp 1031-1041 (2025)
Astrocytes are the most abundant type of glial cell in the central nervous system. Upon injury and inflammation, astrocytes become reactive and undergo morphological and functional changes. Depending on their phenotypic classification as A1 or A2, re
Externí odkaz:
https://doaj.org/article/9126bf4aab634a41a2063a842291be7d
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Cell adhesion and migration depend on the assembly and disassembly of adhesive structures known as focal adhesions. Cells adhere to the extracellular matrix (ECM) and form these structures via receptors, such as integrins and syndecans, which initiat
Externí odkaz:
https://doaj.org/article/773a618e5e2d4e81ad2082ebe3e5ac84
Autor:
Esteban Palacios, Lorena Lobos-González, Simón Guerrero, Marcelo J. Kogan, Baohai Shao, Jay W. Heinecke, Andrew F. G. Quest, Lisette Leyton, Manuel Valenzuela-Valderrama
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-22 (2023)
Abstract Background Helicobacter pylori (Hp) infects the stomach of 50% of the world’s population. Importantly, chronic infection by this bacterium correlates with the appearance of several extra-gastric pathologies, including neurodegenerative dis
Externí odkaz:
https://doaj.org/article/66bbe09056da4e25ada4d02743ecf618
Autor:
Ramón Pérez-Núñez, Alejandro Chamorro, María Fernanda González, Pamela Contreras, Rocío Artigas, Alejandro H. Corvalán, Brigitte van Zundert, Christopher Reyes, Pablo R. Moya, Ana María Avalos, Pascal Schneider, Andrew F. G. Quest, Lisette Leyton
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-19 (2023)
Abstract Background In response to brain injury or inflammation, astrocytes undergo hypertrophy, proliferate, and migrate to the damaged zone. These changes, collectively known as "astrogliosis", initially protect the brain; however, astrogliosis can
Externí odkaz:
https://doaj.org/article/8f88a252b77145c0982c107e62d40b7f
Autor:
Horacio Maldonado, Lisette Leyton
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Cancer progression and metastasis are processes heavily controlled by the integrin receptor family. Integrins are cell adhesion molecules that constitute the central components of mechanosensing complexes called focal adhesions, which connect the ext
Externí odkaz:
https://doaj.org/article/cc2d98c301434ababe838f25a635d197
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Thy-1 is a cell surface glycosylphosphatidylinositol (GPI)-anchored glycoprotein that bears a broad mosaic of biological roles across various cell types. Thy-1 displays strong physiological and pathological implications in development, cancer, immuni
Externí odkaz:
https://doaj.org/article/b7bfe9b3beed4601ae816df4a1cb35f3
Autor:
Alejandra Valdivia, Areli Cárdenas, Marianne Brenet, Horacio Maldonado, Milene Kong, Jorge Díaz, Keith Burridge, Pascal Schneider, Alejandra San Martín, Rafael García-Mata, Andrew F. G. Quest, Lisette Leyton
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-19 (2020)
Abstract Background Syndecans regulate cell migration thus having key roles in scarring and wound healing processes. Our previous results have shown that Thy-1/CD90 can engage both αvβ3 integrin and Syndecan-4 expressed on the surface of astrocytes
Externí odkaz:
https://doaj.org/article/d6664e34183148169b7735a292650ae3
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Acute skin wound healing is a multistage process consisting of a plethora of tightly regulated signaling events in specialized cells. The Thy-1 (CD90) glycoprotein interacts with integrins and the heparan sulfate proteoglycan syndecan 4, generating a
Externí odkaz:
https://doaj.org/article/0b4c730bcdf84707832a04990b5c4486
Autor:
Leonardo A. Pérez, Aysha Rashid, J. Dale Combs, Pascal Schneider, Andrés Rodríguez, Khalid Salaita, Lisette Leyton
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Astrocyte reactivity is associated with poor repair capacity after injury to the brain, where chemical and physical changes occur in the damaged zone. Astrocyte surface proteins, such as integrins, are upregulated, and the release of pro-inflammatory
Externí odkaz:
https://doaj.org/article/9275d3001d4b472b928b77bcd3aa6398
Autor:
Marianne Brenet, Samuel Martínez, Ramón Pérez-Nuñez, Leonardo A. Pérez, Pamela Contreras, Jorge Díaz, Ana María Avalos, Pascal Schneider, Andrew F. G. Quest, Lisette Leyton
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Cancer cell adhesion to the vascular endothelium is an important step in tumor metastasis. Thy-1 (CD90), a cell adhesion molecule expressed in activated endothelial cells, has been implicated in melanoma metastasis by binding to integrins present in
Externí odkaz:
https://doaj.org/article/7837a62594974388907d6aa8a21149c8