Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Lisete C Michelini"'
Autor:
Sebastião D Silva, Zaira P Jara, Roseli Peres, Larissa S Lima, Cristóforo Scavone, Augusto C Montezano, Rhian M Touyz, Dulce E Casarini, Lisete C Michelini
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189535 (2017)
Exercise training reduces renin-angiotensin system (RAS) activation, decreases plasma and tissue oxidative stress and inflammation in hypertension. However, the temporal nature of these phenomena in response to exercise is unknown. We sought to deter
Externí odkaz:
https://doaj.org/article/2ee0a187fa494a2c8984149227aafbd1
Autor:
Mariana Makuch-Martins, Camilla G. Vieira-Morais, Sany M. Perego, Adriana Ruggeri, Alexandre Ceroni, Lisete C. Michelini
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
BackgroundHypertension is characterized by upregulation of the renin–angiotensin system, increased blood–brain barrier (BBB) permeability, microglia activation within autonomic nuclei, and an intense sympathoexcitation. There is no information on
Externí odkaz:
https://doaj.org/article/c152a371ef94414ba0b419c0099ca5fb
Autor:
Gustavo S Masson, Anand R Nair, Rahul B Dange, Pedro Paulo Silva-Soares, Lisete C Michelini, Joseph Francis
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122850 (2015)
Toll-like receptor 4 (TLR4) signaling induces tissue pro-inflammatory cytokine release and endoplasmic reticulum (ER) stress. We examined the role of TLR4 in autonomic dysfunction and the contribution of ER stress.Our study included animals divided i
Externí odkaz:
https://doaj.org/article/dfd9302cb75a4048b630d95d18f059c1
Autor:
Gustavo S Masson, Tassia S R Costa, Lidia Yshii, Denise C Fernandes, Pedro Paulo Silva Soares, Francisco R Laurindo, Cristoforo Scavone, Lisete C Michelini
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e94927 (2014)
Baroreflex dysfunction, oxidative stress and inflammation, important hallmarks of hypertension, are attenuated by exercise training. In this study, we investigated the relationships and time-course changes of cardiovascular parameters, pro-inflammato
Externí odkaz:
https://doaj.org/article/1146112b3cfb491d9751ca0501387e1c
Autor:
Vanessa B. Candido, Sany M. Perego, Alexandre Ceroni, Martin Metzger, Alison Colquhoun, Lisete C. Michelini
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction: Chronic hypertension is accompanied by either blood-brain barrier (BBB) leakage and autonomic dysfunction. There is no consensus on the mechanism determining increased BBB permeability within autonomic areas. While some reports suggeste
Externí odkaz:
https://doaj.org/article/83feaa3b87d14e28959124882dbc0d8c
Autor:
Hiviny de Ataides Raquel, Gustavo Masson, Sany Martins Pérego, Alison Colquhoun, Leonardo Jensen, Lisete C Michelini
Publikováno v:
Circulation. 144
Introduction: Besides intense renin-angiotensin system activation and sympathoexcitation, heart failure (HF) is accompanied by marked autonomic dysfunction. We showed previously in hypertensive rats that blood-brain barrier (BBB) dysfunction in preau
Publikováno v:
Frontiers in Physiology
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Frontiers in Physiology, Vol 12 (2021)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Frontiers in Physiology, Vol 12 (2021)
Remodeling of capillary rarefaction and deleterious arteries are characteristic hallmarks of hypertension that are partially corrected by exercise training. In addition, experimental evidence showed capillary rarefaction within the brain cortex and r
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Previous studies have shown that baroreceptors- and chemoreceptors-denervated SHR exhibit impaired central autonomic circuitry and worsening of the cardiovascular function. It was also known that exercise training (T) ameliorates the autonomic contro
Autor:
Luciana A. Campos, Jose Cipolla-Neto, Fernanda G. Amaral, Lisete C. Michelini, Michael Bader, Ovidiu C. Baltatu
Publikováno v:
International Journal of Hypertension, Vol 2013 (2013)
Accumulating evidence indicates that various biological and neuroendocrine circadian rhythms may be disrupted in cardiovascular and metabolic disorders. These circadian alterations may contribute to the progression of disease. Our studies direct to a
Externí odkaz:
https://doaj.org/article/dab62b2a8b154acd95ca9b15ef42a9c1
Autor:
Nilson C, Ferreira-Junior, Adriana, Ruggeri, Sebastião D, Silva, Thais T, Zampieri, Alexandre, Ceroni, Lisete C, Michelini
Publikováno v:
Physiological Reports
GABAergic inhibitory input within the paraventricular hypothalamic nucleus (PVN) plays a key role in restraining sympathetic outflow. Although experimental evidence has shown depressed GABAA receptor function plus sympathoexcitation in hypertension a