Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Liselotte E. Jensen"'
Publikováno v:
Vaccines, Vol 12, Iss 8, p 837 (2024)
Herpes simplex virus-1 (HSV-1) is common and can cause significant disease in humans. Unfortunately, efforts to develop effective vaccines against HSV-1 have so far failed. A detailed understanding of how the virus infects its host and how the host m
Externí odkaz:
https://doaj.org/article/e2a276ec171142c1bcebb86f0b8c1723
Publikováno v:
Cells, Vol 13, Iss 9, p 787 (2024)
IL-36 cytokines are emerging as beneficial in immunity against pathogens and cancers but can also be detrimental when dysregulated in autoimmune and autoinflammatory conditions. Interest in targeting IL-36 activity for therapeutic purposes is rapidly
Externí odkaz:
https://doaj.org/article/e93482263f9f44c58c47217b1d93913a
Autor:
Liselotte E. Jensen
Publikováno v:
Viruses, Vol 15, Iss 7, p 1422 (2023)
Pellino proteins are a family of evolutionarily conserved ubiquitin ligases involved in intracellular signaling in a wide range of cell types. They are essential for microbe detection and the initiation of innate and adaptive immune responses. Some v
Externí odkaz:
https://doaj.org/article/e3afb839a41e40c9974839057060f3e6
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Herpes simplex virus-1 (HSV-1) suppresses the induction of interferon to evade antiviral immunity. Here, Wang et al. show that during HSV-1 infection, IL-36 increases cellular sensitivity to interferon through induction of IRF1 and the interferon rec
Externí odkaz:
https://doaj.org/article/3073fa03cb584d1194574e47cd64e772
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract Interleukin-36 (IL-36) represents three cytokines, IL-36α, IL-36β and IL-36γ, which bind to the same receptor, IL-1RL2; however, their physiological function(s) remain poorly understood. Here, the role of IL-36 in immunity against HSV-1 w
Externí odkaz:
https://doaj.org/article/7b7a12157bfa4f488dd7a6d2de90cae1
Autor:
Pilar Alvarez, Liselotte E. Jensen
Publikováno v:
Mediators of Inflammation, Vol 2016 (2016)
Generalized pustular psoriasis (GPP) is a severe form of psoriasis that can be caused by missense mutations in the interleukin-36 (IL-36) receptor antagonist. In addition to neutrophil rich skin inflammation, GPP patients typically also experience an
Externí odkaz:
https://doaj.org/article/4182c587db594e859ac68c8debf0ef88
Publikováno v:
BioTechniques, Vol 35, Iss 1, Pp 54-58 (2003)
Externí odkaz:
https://doaj.org/article/d3c7428a96344438a14e64127565a548
Publikováno v:
Journal of Investigative Dermatology. 143:639-647.e2
Nearly all adults are infected with one or more herpes viruses. The most common are herpes simplex virus (HSV)-1 and HSV-2, which upon reactivation can cause painful skin and mucosal erosions. Patients who are immune compromised often experience freq
Publikováno v:
J Invest Dermatol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e257f06d92e4d3b894350e2ba4c57a0
https://europepmc.org/articles/PMC8688218/
https://europepmc.org/articles/PMC8688218/