Syndecan-1 Stimulates Adult Neurogenesis in the Mouse Ventricular-Subventricular Zone after Injury

Autor: Marc-André Mouthon, Lise Morizur, Léa Dutour, Donovan Pineau, Thierry Kortulewski, François D. Boussin

Publikováno v: iScience, Vol 23, Iss 12, Pp 101784- (2020)

Summary: The production of neurons from neural stem cells (NSCs) persists throughout life in the mouse ventricular-subventricular zone (V-SVZ). We have previously reported that NSCs from adult V-SVZ are contained in cell populations expressing the ca

Externí odkaz: https://doaj.org/article/9e6b35aed5df4132b10eabc8c39e3dff

The Future of Regenerative Medicine: Cell Therapy Using Pluripotent Stem Cells and Acellular Therapies Based on Extracellular Vesicles

Autor: Margot Jarrige, Elie Frank, Elise Herardot, Sabrina Martineau, Annabelle Darle, Manon Benabides, Sophie Domingues, Olivier Chose, Walter Habeler, Judith Lorant, Christine Baldeschi, Cécile Martinat, Christelle Monville, Lise Morizur, Karim Ben M’Barek

Publikováno v: Cells, Vol 10, Iss 2, p 240 (2021)

The rapid progress in the field of stem cell research has laid strong foundations for their use in regenerative medicine applications of injured or diseased tissues. Growing evidences indicate that some observed therapeutic outcomes of stem cell-base

Externí odkaz: https://doaj.org/article/67270406f59d4f5b8cad23d51a4e34b9

Distributed automated manufacturing of pluripotent stem cell products

Autor: Glyn Stacey, Mark J.S. McCall, David J. Williams, Lise Morizur, Léa Lesueur, Michael M. Gepp, Heiko Zimmermann, Jennifer Man, Maryam Shariatzadeh, André Schulz, Amit Chandra, Olivier Chose, Orla O'Shea, Samantha L. Wilson, Julia C. Neubauer, Elsa Abranches, Zoe Hewitt

Publikováno v: The International Journal, Advanced Manufacturing Technology

Establishing how to effectively manufacture cell therapies is an industry-level problem. Decentralised manufacturing is of increasing importance, and its challenges are recognised by healthcare regulators with deviations and comparability issues rece

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c3b84f15340e8633f3a07a51dffeb61
https://doi.org/10.1007/s00170-019-04516-1

Identification of thiostrepton as a pharmacological approach to rescue misfolded alpha-sarcoglycan mutant proteins from degradation

Autor: Lise Morizur, Justine Marsolier, Anne Bigot, Manon Benabides, Isabelle Richard, Xavier Nissan, Gurvan Mahé, Celine Bruge, Nathalie Bourg, Margot Jarrige, Sara F. Henriques, Johana Tournois, Lucile Hoch

Publikováno v: Scientific Reports
Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-019-43399-w⟩
Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-019-43399-w⟩
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)

Limb-girdle muscular dystrophy type 2D (LGMD2D) is characterized by a progressive proximal muscle weakness. LGMD2D is caused by mutations in the gene encoding α-sarcoglycan (α-SG), a dystrophin-associated glycoprotein that plays a key role in the m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fae1204aeca4ba65f8343b226ef9311
https://hal.sorbonne-universite.fr/hal-02138777/file/s41598-019-43399-w.pdf

Automation of human pluripotent stem cell differentiation toward retinal pigment epithelial cells for large-scale productions

Autor: Christelle Monville, Florian Regent, Lise Morizur, Karim Ben M'Barek, Alexandra Plancheron, Walter Habeler, Léa Lesueur

Publikováno v: Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)

Dysfunction or death of retinal pigment epithelial (RPE) cells is involved in some forms of Retinitis Pigmentosa and in age-related macular degeneration (AMD). Since there is no cure for most patients affected by these diseases, the transplantation o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353b499841a11808ecc1f2ebda9ccfbf
https://doi.org/10.1038/s41598-019-47123-6