Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Lise Bjørkhaug"'
Autor:
Anita Ryningen, Kari Rostad, Elisabeth Ersvær, Gry Sjøholt, Gøran Paulsen, Hilde Gundersen, Morten Kristoffersen, Lise Bjørkhaug
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Background: Heavy strength (HS) and short-sprint (SS) are commonly used training methods for competitive road cyclists, with the aim to improve the anaerobic power and short time cycling performance. Knowledge of how such training methods affects bio
Externí odkaz:
https://doaj.org/article/463578e1f4c44a899af471f721ae3ac3
Publikováno v:
Bioingeniøren, Vol 57, Iss 6, Pp 30-36 (2022)
Background: MODY (Maturity-Onset Diabetes of the Young) is an inherited form of non-insulin dependent diabetes mellitus, caused by a pathogenic gene variant in one of many MODY genes. The purpose of this article is to highlight the importance of func
Externí odkaz:
https://doaj.org/article/929cb4cc8e6747ca963d3d188c1bcc00
Autor:
Marcus S. Dasa, Morten Kristoffersen, Elisabeth Ersvær, Lars Peder Bovim, Lise Bjørkhaug, Rolf Moe-Nilssen, Jørn V. Sagen, Inger Haukenes
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
PurposeThe female menstrual cycle (MC) is characterized by hormonal fluctuations throughout its different phases. However, research regarding its effect on athletic performance in high level athletes is sparse. The aim of this study was to (i) invest
Externí odkaz:
https://doaj.org/article/eec67276751b4fbea8106e8381b14939
Autor:
Anne Cathrine Baun Thuesen, Frederik Filip Stæger, Alba Kaci, Marie Holm Solheim, Ingvild Aukrust, Emil Jørsboe, Cindy G. Santander, Mette K. Andersen, Zilong Li, Arthur Gilly, Sara Elizabeth Stinson, Anette Prior Gjesing, Peter Bjerregaard, Michael Lynge Pedersen, Christina Viskum Lytken Larsen, Niels Grarup, Marit E. Jørgensen, Eleftheria Zeggini, Lise Bjørkhaug, Pål Rasmus Njølstad, Anders Albrechtsen, Ida Moltke, Torben Hansen
Publikováno v:
The Lancet Regional Health-Europe
Thuesen, A C B, Stæger, F F, Kaci, A, Solheim, M H, Aukrust, I, Jørsboe, E, Santander, C G, Andersen, M K, Li, Z, Gilly, A, Stinson, S E, Gjesing, A P, Bjerregaard, P, Pedersen, M L, Larsen, C V L, Grarup, N, Jørgensen, M E, Zeggini, E, Bjørkhaug, L, Njølstad, P R, Albrechtsen, A, Moltke, I & Hansen, T 2023, ' A novel splice-affecting HNF1A variant with large population impact on diabetes in Greenland ', The Lancet Regional Health-Europe, vol. 24, 100529 . https://doi.org/10.1016/j.lanepe.2022.100529
Thuesen, A C B, Stæger, F F, Kaci, A, Solheim, M H, Aukrust, I, Jørsboe, E, Santander, C G, Andersen, M K, Li, Z, Gilly, A, Stinson, S E, Gjesing, A P, Bjerregaard, P, Pedersen, M L, Larsen, C V L, Grarup, N, Jørgensen, M E, Zeggini, E, Bjørkhaug, L, Njølstad, P R, Albrechtsen, A, Moltke, I & Hansen, T 2023, ' A novel splice-affecting HNF1A variant with large population impact on diabetes in Greenland ', The Lancet Regional Health-Europe, vol. 24, 100529 . https://doi.org/10.1016/j.lanepe.2022.100529
Background: The genetic disease architecture of Inuit includes a large number of common high-impact variants. Identification of such variants contributes to our understanding of the genetic aetiology of diseases and improves global equity in genomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::630bbe59ff3adfcfcc41cec4442f73bb
https://hdl.handle.net/11250/3063542
https://hdl.handle.net/11250/3063542
Autor:
Lauren A. Stalbow, Michael H. Preuss, Roelof A. J. Smit, Nathalie Chami, Lise Bjørkhaug, Ingvild Aukrust, Anna L. Gloyn, Ruth J. F. Loos
Publikováno v:
Diabetologia
Stalbow, L A, Preuss, M H, Smit, R A J, Chami, N, Bjørkhaug, L, Aukrust, I, Gloyn, A L & Loos, R J F 2023, ' The contribution of functional HNF1A variants and polygenic susceptibility to risk of type 2 diabetes in ancestrally diverse populations ', Diabetologia, vol. 66, pp. 116-126 . https://doi.org/10.1007/s00125-022-05806-2
Stalbow, L A, Preuss, M H, Smit, R A J, Chami, N, Bjørkhaug, L, Aukrust, I, Gloyn, A L & Loos, R J F 2023, ' The contribution of functional HNF1A variants and polygenic susceptibility to risk of type 2 diabetes in ancestrally diverse populations ', Diabetologia, vol. 66, pp. 116-126 . https://doi.org/10.1007/s00125-022-05806-2
Aims/hypothesis We examined the contribution of rare HNF1A variants to type 2 diabetes risk and age of diagnosis, and the extent to which their impact is affected by overall genetic susceptibility, across three ancestry groups. Methods Using exome se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96a804f0062bcda997dd44bc0621f49e
https://hdl.handle.net/11250/3044350
https://hdl.handle.net/11250/3044350
Autor:
Lauren A, Stalbow, Michael H, Preuss, Roelof A J, Smit, Nathalie, Chami, Lise, Bjørkhaug, Ingvild, Aukrust, Anna L, Gloyn, Ruth J F, Loos
Publikováno v:
Diabetologia. 66(1)
We examined the contribution of rare HNF1A variants to type 2 diabetes risk and age of diagnosis, and the extent to which their impact is affected by overall genetic susceptibility, across three ancestry groups.Using exome sequencing data of 160,615
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8f943c351e66ddfcaa49dfc8069b1abf
https://pubmed.ncbi.nlm.nih.gov/36216889
https://pubmed.ncbi.nlm.nih.gov/36216889
Autor:
Tandi E. Matsha, Shanel Raghubeer, Gloudina M. Hon, Saarah F G Davids, Abegail M Tshivhase, Rajiv T Erasmus, Lise Bjørkhaug
Publikováno v:
The Application of Clinical Genetics. 13:209-219
Background and aim Maturity-onset diabetes of the young (MODY) is the result of single gene variants. To date, fourteen different MODY subtypes have been described. Variants in genes coding for glucokinase (GCK, MODY2) and hepatic nuclear factor 1 al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6c85f93c7df5d9e08435e7d404a8955
https://doi.org/10.2147/tacg.s281872
https://doi.org/10.2147/tacg.s281872
Functional Analyses of HNF1A-MODY Variants Refine the Interpretation of Identified Sequence Variants
Autor:
Jana Malikova, Pavla Dvorakova Kankova, Janniche Torsvik, Petra Dusatkova, Stepanka Pruhova, Klara Vesela, Alba Kaci, Ingvild Aukrust, Lise Bjørkhaug, Pål R. Njølstad
Publikováno v:
e1377-e1386
Journal of Clinical Endocrinology and Metabolism
Journal of Clinical Endocrinology and Metabolism
Context While rare variants of the hepatocyte nuclear factor-1 alpha (HNF1A) gene can cause maturity-onset diabetes of the young (HNF1A-MODY), other variants can be risk factors for the development of type 2 diabetes. As has been suggested by the Ame
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2e18edabd2e6536fcbaa65942cba5e
https://doi.org/10.1210/clinem/dgaa051
https://doi.org/10.1210/clinem/dgaa051
Autor:
Laura Kind, Arne Raasakka, Janne Molnes, Ingvild Aukrust, Lise Bjørkhaug, Pål Rasmus Njølstad, Petri Kursula, Thomas Arnesen
Publikováno v:
Journal of Biological Chemistry
The journal of biological chemistry 298(4), 101803 (2022). doi:10.1016/j.jbc.2022.101803
The journal of biological chemistry 298(4), 101803 (2022). doi:10.1016/j.jbc.2022.101803
JBC papers in press 298(4), 101803 (2022). doi:10.1016/j.jbc.2022.101803
Hepatocyte nuclear factor 1A (HNF-1A) is a transcription factor expressed in several embryonic and adult tissues, modulating the expression of numerous target genes. Pathog
Hepatocyte nuclear factor 1A (HNF-1A) is a transcription factor expressed in several embryonic and adult tissues, modulating the expression of numerous target genes. Pathog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deabbd37ee49cb8f0f2b55f48175fa7d