Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Lise, Verbruggen"'
Autor:
Lise Verbruggen, Lisa Verheggen, Greetje Vanhoutte, Catherine Loly, Willem Lybaert, Ivan Borbath, Philippe Vergauwe, Koen Hendrickx, Celine Debeuckelaere, Amy de Haar-Holleman, Jean-Luc Van Laethem, Marc Peeters
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 15 (2023)
Background: Currently, nanoliposomal irinotecan (nal-IRI) + 5-fluorouracil/folinic acid (5-FU/LV) is the only approved second-line treatment for patients suffering from metastatic pancreatic ductal adenocarcinoma (mPDAC). However, also other chemothe
Externí odkaz:
https://doaj.org/article/e404b2d307b14c2b98a13af2a613b0ab
Autor:
Angelina Konnova, Fien H. R. De Winter, Akshita Gupta, Lise Verbruggen, An Hotterbeekx, Matilda Berkell, Laure-Anne Teuwen, Greetje Vanhoutte, Bart Peeters, Silke Raats, Isolde Van der Massen, Sven De Keersmaecker, Yana Debie, Manon Huizing, Pieter Pannus, Kristof Y. Neven, Kevin K. Ariën, Geert A. Martens, Marc Van Den Bulcke, Ella Roelant, Isabelle Desombere, Sébastien Anguille, Zwi Berneman, Maria E. Goossens, Herman Goossens, Surbhi Malhotra-Kumar, Evelina Tacconelli, Timon Vandamme, Marc Peeters, Peter van Dam, Samir Kumar-Singh
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundPatients with cancer, especially hematological cancer, are at increased risk for breakthrough COVID-19 infection. So far, a predictive biomarker that can assess compromised vaccine-induced anti-SARS-CoV-2 immunity in cancer patients has not
Externí odkaz:
https://doaj.org/article/ad857598e2b741baaf1d0d02701cbefe
Autor:
Eduard Bentea, Laura De Pauw, Lise Verbruggen, Lila C. Winfrey, Lauren Deneyer, Cynthia Moore, Giulia Albertini, Hideyo Sato, Ann Van Eeckhaut, Charles K. Meshul, Ann Massie
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
The astrocytic cystine/glutamate antiporter system xc– (with xCT as the specific subunit) imports cystine in exchange for glutamate and has been shown to interact with multiple pathways in the brain that are dysregulated in age-related neurological
Externí odkaz:
https://doaj.org/article/a6d327e1e24344a8926ec84d90535739
Autor:
Lise Verbruggen, Lindsay Sprimont, Eduard Bentea, Pauline Janssen, Azzedine Gharib, Lauren Deneyer, Laura De Pauw, Olaya Lara, Hideyo Sato, Charles Nicaise, Ann Massie
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Despite ample evidence for the therapeutic potential of inhibition of the cystine/glutamate antiporter system xc− in neurological disorders and in cancer, none of the proposed inhibitors is selective. In this context, a lot of research has been per
Externí odkaz:
https://doaj.org/article/e5c8b01f7c4943ae966ece9e1e32fa8f
Autor:
Peter A. van Dam, Marc Peeters, Eva Lion, Christof Vulsteke, Evelien L.J. Smits, Hans Prenen, Annelies Janssens, Sébastien Anguille, Kevin K. Ariën, Pieter Pannus, Maria E. Goossens, Bart Peeters, Debbie Le Blon, Lisa Verheggen, Elly Marcq, Greetje Vanhoutte, Lise Verbruggen, Laure-Anne Teuwen, Lieselot Croes, Timon Vandamme, Jonas R.M. Van Audenaerde, Yana Debie
Supplementary Figure 3: Gating strategy for a representative sample
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2741776c36345c050a0d66800abd6c49
https://doi.org/10.1158/1078-0432.22489859.v1
https://doi.org/10.1158/1078-0432.22489859.v1
Autor:
Peter A. van Dam, Marc Peeters, Eva Lion, Christof Vulsteke, Evelien L.J. Smits, Hans Prenen, Annelies Janssens, Sébastien Anguille, Kevin K. Ariën, Pieter Pannus, Maria E. Goossens, Bart Peeters, Debbie Le Blon, Lisa Verheggen, Elly Marcq, Greetje Vanhoutte, Lise Verbruggen, Laure-Anne Teuwen, Lieselot Croes, Timon Vandamme, Jonas R.M. Van Audenaerde, Yana Debie
Supplementary Tables S1-S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::282f4a687bb9c01fc005f2df42cb5cd4
https://doi.org/10.1158/1078-0432.22489847.v1
https://doi.org/10.1158/1078-0432.22489847.v1
Autor:
Peter A. van Dam, Marc Peeters, Eva Lion, Christof Vulsteke, Evelien L.J. Smits, Hans Prenen, Annelies Janssens, Sébastien Anguille, Kevin K. Ariën, Pieter Pannus, Maria E. Goossens, Bart Peeters, Debbie Le Blon, Lisa Verheggen, Elly Marcq, Greetje Vanhoutte, Lise Verbruggen, Laure-Anne Teuwen, Lieselot Croes, Timon Vandamme, Jonas R.M. Van Audenaerde, Yana Debie
Purpose:Patients with cancer display reduced humoral responses after double-dose COVID-19 vaccination, whereas their cellular response is more comparable with that in healthy individuals. Recent studies demonstrated that a third vaccination dose boos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d35b81c8b11e3d31f5d0b584ab89ff8f
https://doi.org/10.1158/1078-0432.c.6533054
https://doi.org/10.1158/1078-0432.c.6533054
Autor:
Lise Verbruggen, Gamze Ates, Olaya Lara, Jolien De Munck, Agnès Villers, Laura De Pauw, Sigrid Ottestad-Hansen, Sho Kobayashi, Pauline Beckers, Pauline Janssen, Hideyo Sato, Yun Zhou, Emmanuel Hermans, Rose Njemini, Lutgarde Arckens, Niels C. Danbolt, Dimitri De Bundel, Joeri L. Aerts, Kurt Barbé, Benoit Guillaume, Laurence Ris, Eduard Bentea, Ann Massie
Publikováno v:
Molecular Psychiatry, (2022)
The cystine/glutamate antiporter system xc− has been identified as the major source of extracellular glutamate in several brain regions as well as a modulator of neuroinflammation, and genetic deletion of its specific subunit xCT (xCT−/−) is pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb057e10d0c8d517f124d8596bbdc30e
https://doi.org/10.1038/s41380-022-01470-5
https://doi.org/10.1038/s41380-022-01470-5
Autor:
Yana Debie, Jonas R.M. Van Audenaerde, Timon Vandamme, Lieselot Croes, Laure-Anne Teuwen, Lise Verbruggen, Greetje Vanhoutte, Elly Marcq, Lisa Verheggen, Debbie Le Blon, Bart Peeters, Maria E. Goossens, Pieter Pannus, Kevin K. Ariën, Sébastien Anguille, Annelies Janssens, Hans Prenen, Evelien L.J. Smits, Christof Vulsteke, Eva Lion, Marc Peeters, Peter A. van Dam
Publikováno v:
Clinical cancer research
Purpose: Patients with cancer display reduced humoral responses after double-dose COVID-19 vaccination, whereas their cellular response is more comparable with that in healthy individuals. Recent studies demonstrated that a third vaccination dose boo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f575bbfaf9bcf3134856b5021f1a87c2
https://hdl.handle.net/10067/1925000151162165141
https://hdl.handle.net/10067/1925000151162165141
Autor:
Angelina Konnova, Fien HR De Winter, Akshita Gupta, Lise Verbruggen, An Hotterbeekx, Matilda Berkell, Laure-Anne Teuwen, Greetje Vanhoutte, Bart Peeters, Silke Raats, Isolde Van der Massen, Sven De Keersmaecker, Yana Debie, Manon Huizing, Pieter Pannus, Kristof Y Neven, Kevin K Ariën, Geert A. Martens, Marc Van Den Bulcke, Ella Roelant, Isabelle Desombere, Sébastien Anguille, Zwi Berneman, Maria E Goossens, Herman Goossens, Surbhi Malhotra-Kumar, Evelina Taconelli, Timon Vandamme, Marc Peeters, Peter van Dam, Samir Kumar-Singh
BackgroundPatients with cancer, especially haematological cancer, are at increased risk for breakthrough COVID-19 infection. However, so far, a predictive biomarker that can assess compromised vaccine-induced anti-SARS-CoV-2 immunity in cancer patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73724b23ab84d307f26b1c7e555afd15
https://doi.org/10.1101/2022.09.25.22280267
https://doi.org/10.1101/2022.09.25.22280267