Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Lisbeth H. Olsen"'
Autor:
Maiken B. T. Bach, Camilla L. Stougaard, Maria S. Thøfner, Maria J. Reimann, Ulrik Westrup, Jørgen Koch, Merete Fredholm, Torben Martinussen, Mette Berendt, Lisbeth H. Olsen
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 2, Pp 904-912 (2024)
Abstract Background Syringomyelia (SM) and myxomatous mitral valve disease (MMVD) are highly prevalent in Cavalier King Charles spaniels (CKCS). Cardiac status in CKCS with and without SM is currently unknown. Objectives To investigate the associatio
Externí odkaz:
https://doaj.org/article/22cc1d2f332c4c37b1aa63fb2140adf8
Autor:
Maria J. Reimann, Daniel N. Faisst, Mads Knold, Kathryn M. Meurs, Joshua A. Stern, Signe E. Cremer, Jacob E. Møller, Ingrid Ljungvall, Jens Häggström, Lisbeth H. Olsen
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 37, Iss 6, Pp 2145-2156 (2023)
Abstract Background A variant in the canine phosphodiesterase (PDE) 5A gene (PDE5A:E90K) is associated with decreased concentrations of circulating cyclic guanosine monophosphate (cGMP) and response to PDE5 inhibitor treatment. Pimobendan is a PDE in
Externí odkaz:
https://doaj.org/article/cd502d1817ad4c5a967b5c356fee7e03
Autor:
Maria J. Reimann, Merete Fredholm, Signe E. Cremer, Liselotte B. Christiansen, Kathryn M. Meurs, Jacob E. Møller, Jens Häggström, Jens Lykkesfeldt, Lisbeth H. Olsen
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 35, Iss 6, Pp 2596-2606 (2021)
Abstract Background The neurotransmitter serotonin (5‐HT) affects valvular degeneration and dogs with myxomatous mitral valve disease (MMVD) exhibit alterations in 5‐HT signaling. In Maltese dogs, 3 single nucleotide polymorphisms (SNPs) in the 5
Externí odkaz:
https://doaj.org/article/9c90b0938ef34ce4bd4c80f500da3300
Autor:
Mille K. Lyhne, Andreas Vegge, Gro Klitgaard Povlsen, Rita Slaaby, Jonas Kildegaard, Ulrik Pedersen-Bjergaard, Lisbeth H. Olsen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The potentially fatal cardiovascular effects of hypoglycaemia are not well understood and large animal models of the counter-regulatory responses and cardiovascular consequences of insulin-induced hypoglycaemia are needed to understand the m
Externí odkaz:
https://doaj.org/article/76b2d03c79b64068a84ef05415463376
Autor:
Liselotte B. Christiansen, Maria J. Reimann, Anne Marie V. Schou-Pedersen, Steen Larsen, Jens Lykkesfeldt, Lisbeth H. Olsen
Publikováno v:
Antioxidants, Vol 10, Iss 2, p 161 (2021)
Congestive heart failure (CHF) has been associated with depleted myocardial coenzyme Q10 (Q10) concentrations in human patients. The aim of this study was to investigate associations between myocardial Q10 concentrations and myxomatous mitral valve d
Externí odkaz:
https://doaj.org/article/e0aaf3cd832c4874836601367f44d396
Autor:
Liselotte B. Christiansen, Malene K. Morsing, Maria Josefine Reimann, Torben Martinussen, Zita Birlie, Anne Marie V. Schou-Pedersen, Jens Lykkesfeldt, Lisbeth H. Olsen
Publikováno v:
Antioxidants, Vol 9, Iss 9, p 827 (2020)
Coenzyme Q10 (Q10) is a mitochondrial cofactor and an antioxidant with the potential to combat oxidative stress in heart failure. This study aims to determine the pharmacokinetics of repeated oral dosing of Q10 in Cavalier King Charles Spaniels (CKCS
Externí odkaz:
https://doaj.org/article/9ae8df89bbd74c0ea2d43d53e029a8c3
Autor:
Maria J. Reimann, Signe Cremer, Liselotte Christiansen, Emil Ibragimov, Fei Gao, Susanna Cirera, Merete Fredholm, Lisbeth H. Olsen, Peter Karlskov-Mortensen
We here report the results of a mitral valve transcriptome study designed to identify genes and molecular pathways involved in development of myxomatous mitral valve disease (MMVD) in dogs. The study is focused on a cohort of elderly age-matched dogs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::098a4c7bd8688b4babdd9643e0ed4b63
https://doi.org/10.21203/rs.3.rs-2458329/v1
https://doi.org/10.21203/rs.3.rs-2458329/v1
Autor:
Liselotte B Christiansen, Kathryn M. Meurs, Jacob E. Møller, Signe E. Cremer, Lisbeth H. Olsen, Jens Lykkesfeldt, M.J. Reimann, Jens Häggström, Merete Fredholm
Publikováno v:
Journal of Veterinary Internal Medicine
Journal of Veterinary Internal Medicine, Vol 35, Iss 6, Pp 2596-2606 (2021)
Reimann, M J, Fredholm, M, Cremer, S E, Christiansen, L B, Meurs, K M, Møller, J E, Häggström, J, Lykkesfeldt, J & Olsen, L H 2021, ' Polymorphisms in the serotonin transporter gene and circulating concentrations of neurotransmitters in Cavalier King Charles Spaniels with myxomatous mitral valve disease ', Journal of Veterinary Internal Medicine, vol. 35, no. 6, pp. 2596-2606 . https://doi.org/10.1111/jvim.16277
Journal of Veterinary Internal Medicine, Vol 35, Iss 6, Pp 2596-2606 (2021)
Reimann, M J, Fredholm, M, Cremer, S E, Christiansen, L B, Meurs, K M, Møller, J E, Häggström, J, Lykkesfeldt, J & Olsen, L H 2021, ' Polymorphisms in the serotonin transporter gene and circulating concentrations of neurotransmitters in Cavalier King Charles Spaniels with myxomatous mitral valve disease ', Journal of Veterinary Internal Medicine, vol. 35, no. 6, pp. 2596-2606 . https://doi.org/10.1111/jvim.16277
BACKGROUND: The neurotransmitter serotonin (5-HT) affects valvular degeneration and dogs with myxomatous mitral valve disease (MMVD) exhibit alterations in 5-HT signaling. In Maltese dogs, 3 single nucleotide polymorphisms (SNPs) in the 5-HT transpor
Autor:
Maiken Mellergaard, Lisbeth H. Olsen, Ole L. Nielsen, Dorte Frees, M.J. Reimann, Søren Skov, Maria Nygaard Larsen
Publikováno v:
APMIS. 130:359-370
In this descriptive pilot study, we aim to establish a porcine Staphylococcus aureus skin infection model by subcutaneous injection (s.c.) of the porcine S54F9 S. aureus strain in the groin area. Six pigs were used in the study: Five pigs were inject
Autor:
Lisbeth H. Olsen, Steen Larsen, Patrick Orlando, Michal Ciborowski, Torben Martinussen, Claus Desler, Tine Lovsø Dohlmann, Trine Pagh Ludvigsen, Lukasz Szczerbinski, Luca Tiano, Liselotte B Christiansen, Adam Kretowski, Ewa Parfieniuk
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Christiansen, L B, Dohlmann, T L, Ludvigsen, T P, Parfieniuk, E, Ciborowski, M, Szczerbinski, L, Kretowski, A, Desler, C, Tiano, L, Orlando, P, Martinussen, T, Olsen, L H & Larsen, S 2021, ' Atorvastatin impairs liver mitochondrial function in obese Göttingen Minipigs but heart and skeletal muscle are not affected ', Scientific Reports, vol. 11, 2167 . https://doi.org/10.1038/s41598-021-81846-9
Scientific Reports
Christiansen, L B, Dohlmann, T L, Ludvigsen, T P, Parfieniuk, E, Ciborowski, M, Szczerbinski, L, Kretowski, A, Desler, C, Tiano, L, Orlando, P, Martinussen, T, Olsen, L H & Larsen, S 2021, ' Atorvastatin impairs liver mitochondrial function in obese Göttingen Minipigs but heart and skeletal muscle are not affected ', Scientific Reports, vol. 11, 2167 . https://doi.org/10.1038/s41598-021-81846-9
Scientific Reports
Statins lower the risk of cardiovascular events but have been associated with mitochondrial functional changes in a tissue-dependent manner. We investigated tissue-specific modifications of mitochondrial function in liver, heart and skeletal muscle m