Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Lisanne M van Leeuwen"'
Autor:
Trang H Phan, Lisanne M van Leeuwen, Coen Kuijl, Roy Ummels, Gunny van Stempvoort, Alba Rubio-Canalejas, Sander R Piersma, Connie R Jiménez, Astrid M van der Sar, Edith N G Houben, Wilbert Bitter
Publikováno v:
PLoS Pathogens, Vol 14, Iss 8, p e1007247 (2018)
The pathogen Mycobacterium tuberculosis employs a range of ESX-1 substrates to manipulate the host and build a successful infection. Although the importance of ESX-1 secretion in virulence is well established, the characterization of its individual c
Externí odkaz:
https://doaj.org/article/168aa6b95d0e4e7c9b73b8e47bd923a8
Autor:
Charlotte M. Nusman, Linde Snoek, Lisanne M. van Leeuwen, Thomas H. Dierikx, Bo M. van der Weijden, Niek B. Achten, Merijn W. Bijlsma, Douwe H. Visser, Marlies A. van Houten, Vincent Bekker, Tim G. J. de Meij, Ellen van Rossem, Mariet Felderhof, Frans B. Plötz
Publikováno v:
Antibiotics, Vol 12, Iss 3, p 489 (2023)
The difficulty in recognizing early-onset neonatal sepsis (EONS) in a timely manner due to non-specific symptoms and the limitations of diagnostic tests, combined with the risk of serious consequences if EONS is not treated in a timely manner, has re
Externí odkaz:
https://doaj.org/article/612009c0d32f40ba983533868c95082e
Autor:
Lisanne M. van Leeuwen, Martijn van der Kuip, Sameh A. Youssef, Alain de Bruin, Wilbert Bitter, A. Marceline van Furth, Astrid M. van der Sar
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 9, Pp 1111-1122 (2014)
Tuberculous meningitis (TBM) is one of the most severe extrapulmonary manifestations of tuberculosis, with a high morbidity and mortality. Characteristic pathological features of TBM are Rich foci, i.e. brain- and spinal-cord-specific granulomas form
Externí odkaz:
https://doaj.org/article/4c464ff8eb54415287da2bfa6f3a49b1
Autor:
Lisanne M van Leeuwen, Roy Ummels, Sander R. Piersma, Trang H Phan, Coen Kuijl, Gunny van Stempvoort, Alba Rubio-Canalejas, Connie R. Jimenez, Edith N.G. Houben, Astrid M. van der Sar, Wilbert Bitter
Publikováno v:
Phan, T H, van Leeuwen, L M, Kuijl, C, Ummels, R, van Stempvoort, G, Rubio-Canalejas, A, Piersma, S R, Jiménez, C R, van der Sar, A M, Houben, E N G & Bitter, W 2018, ' EspH is a hypervirulence factor for Mycobacterium marinum and essential for the secretion of the ESX-1 substrates EspE and EspF ', PLoS Pathogens, vol. 14, no. 8, pp. e1007247 . https://doi.org/10.1371/journal.ppat.1007247
PLoS Pathogens, 14(8). Public Library of Science
PLoS Pathogens, Vol 14, Iss 8, p e1007247 (2018)
Phan, T H, van Leeuwen, L M, Kuijl, C, Ummels, R, van Stempvoort, G, Rubio-Canalejas, A, Piersma, S R, Jiménez, C R, van der Sar, A M, Houben, E N G & Bitter, W 2018, ' EspH is a hypervirulence factor for Mycobacterium marinum and essential for the secretion of the ESX-1 substrates EspE and EspF ', Plos Pathogens, vol. 14, no. 8, e1007247, pp. 1-26 . https://doi.org/10.1371/journal.ppat.1007247
Plos Pathogens, 14(8):e1007247, 1-26. Public Library of Science
PLoS Pathogens
PLoS Pathogens, 14(8). Public Library of Science
PLoS Pathogens, Vol 14, Iss 8, p e1007247 (2018)
Phan, T H, van Leeuwen, L M, Kuijl, C, Ummels, R, van Stempvoort, G, Rubio-Canalejas, A, Piersma, S R, Jiménez, C R, van der Sar, A M, Houben, E N G & Bitter, W 2018, ' EspH is a hypervirulence factor for Mycobacterium marinum and essential for the secretion of the ESX-1 substrates EspE and EspF ', Plos Pathogens, vol. 14, no. 8, e1007247, pp. 1-26 . https://doi.org/10.1371/journal.ppat.1007247
Plos Pathogens, 14(8):e1007247, 1-26. Public Library of Science
PLoS Pathogens
The pathogen Mycobacterium tuberculosis employs a range of ESX-1 substrates to manipulate the host and build a successful infection. Although the importance of ESX-1 secretion in virulence is well established, the characterization of its individual c
Autor:
Susanne M. A. van der Pol, Lisanne M. van Leeuwen, A. Marceline van Furth, Coen Kuijl, Wilbert Bitter, Helga E. de Vries, Martijn van der Kuip, Maikel Boot, Gunny van Stempvoort, Nicole N. van der Wel, Astrid M. van der Sar, Daisy I. Picavet
Publikováno v:
Cellular microbiology, 20(9):e12858. Wiley-Blackwell
Cellular Microbiology, 20(9):e12858. Wiley-Blackwell
van Leeuwen, L M, Boot, M, Kuijl, C, Picavet, D I, van Stempvoort, G, van der Pol, S M A, de Vries, H E, van der Wel, N N, van der Kuip, M, van Furth, A M, van der Sar, A M & Bitter, W 2018, ' Mycobacteria employ two different mechanisms to cross the blood-brain barrier ', Cellular Microbiology, vol. 20, no. 9, e12858, pp. e12858 . https://doi.org/10.1111/cmi.12858
van Leeuwen, L M, Boot, M, Kuijl, C, Picavet, D I, van Stempvoort, G, van der Pol, S M A, de Vries, H E, van der Wel, N N, van der Kuip, M, van Furth, A M, van der Sar, A M & Bitter, W 2018, ' Mycobacteria employ two different mechanisms to cross the blood-brain barrier ', Cellular Microbiology, vol. 20, no. 9, e1285820 . https://doi.org/10.1111/cmi.12858
Cellular Microbiology
Cellular Microbiology, 20(9):e1285820. Wiley-Blackwell
Cellular Microbiology, 20(9):e12858. Wiley-Blackwell
van Leeuwen, L M, Boot, M, Kuijl, C, Picavet, D I, van Stempvoort, G, van der Pol, S M A, de Vries, H E, van der Wel, N N, van der Kuip, M, van Furth, A M, van der Sar, A M & Bitter, W 2018, ' Mycobacteria employ two different mechanisms to cross the blood-brain barrier ', Cellular Microbiology, vol. 20, no. 9, e12858, pp. e12858 . https://doi.org/10.1111/cmi.12858
van Leeuwen, L M, Boot, M, Kuijl, C, Picavet, D I, van Stempvoort, G, van der Pol, S M A, de Vries, H E, van der Wel, N N, van der Kuip, M, van Furth, A M, van der Sar, A M & Bitter, W 2018, ' Mycobacteria employ two different mechanisms to cross the blood-brain barrier ', Cellular Microbiology, vol. 20, no. 9, e1285820 . https://doi.org/10.1111/cmi.12858
Cellular Microbiology
Cellular Microbiology, 20(9):e1285820. Wiley-Blackwell
Central nervous system (CNS) infection by Mycobacterium tuberculosis is one of the most devastating complications of tuberculosis, in particular in early childhood. In order to induce CNS infection, M. tuberculosis needs to cross specialised barriers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff4861a94dc7493369c285286b4e0ea
https://pure.amc.nl/en/publications/mycobacteria-employ-two-different-mechanisms-to-cross-the-bloodbrain-barrier(a1d728c6-051e-40f9-a7d4-11ccd2c30523).html
https://pure.amc.nl/en/publications/mycobacteria-employ-two-different-mechanisms-to-cross-the-bloodbrain-barrier(a1d728c6-051e-40f9-a7d4-11ccd2c30523).html
Autor:
Xiaoming Fang, Lisanne M. van Leeuwen, Jarema Malicki, Robert Evans, Aleksandra Bojarczuk, Theo Verboom, Astrid M. van der Sar, Kin Ki Jim, Simon A. Johnston
Publikováno v:
Biology Open, 7(2):bio030494. Company of Biologists Ltd
Biology Open, Vol 7, Iss 2 (2018)
van Leeuwen, L M, Evans, R J, Jim, K K, Verboom, T, Fang, X, Bojarczuk, A, Malicki, J, Johnston, S A & van der Sar, A M 2018, ' A transgenic zebrafish model for the in vivo study of the blood and choroid plexus brain barriers using claudin 5 ', Biology Open, vol. 7, no. 2, bio030494 . https://doi.org/10.1242/bio.030494
Biology Open, Vol 7, Iss 2 (2018)
van Leeuwen, L M, Evans, R J, Jim, K K, Verboom, T, Fang, X, Bojarczuk, A, Malicki, J, Johnston, S A & van der Sar, A M 2018, ' A transgenic zebrafish model for the in vivo study of the blood and choroid plexus brain barriers using claudin 5 ', Biology Open, vol. 7, no. 2, bio030494 . https://doi.org/10.1242/bio.030494
The central nervous system (CNS) has specific barriers that protect the brain from potential threats and tightly regulate molecular transport. Despite the critical functions of the CNS barriers, the mechanisms underlying their development and functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80bff2b12e531e675dbfa4a970314949
https://doi.org/10.1101/180653
https://doi.org/10.1101/180653
Autor:
Theo Verboom, Gurdyal S. Besra, Astrid M. van der Sar, Arun K. Mishra, Marion Sparrius, Wilbert Bitter, Esther J. M. Stoop, Gunny van Stempvoort, Nicole N. van der Wel, Susanne A. Raadsen, Ben J. Appelmelk, Maaike van Zon, Nicole N. Driessen, Lisanne M. van Leeuwen, Pascale Bouchier, Jeroen Geurtsen
Publikováno v:
Cellular Microbiology. 15:2093-2108
The causative agent of tuberculosis (TB), Mycobacterium tuberculosis, remains an important worldwide health threat. Although TB is one of the oldest infectious diseases of man, a detailed understanding of the mycobacterial mechanisms underlying patho
Autor:
Marion Sparrius, Robert van de Weerd, Maroeska J. Burggraaf, Ben J. Appelmelk, Elisa Dainese, Lisanne M. van Leeuwen, Jeroen Geurtsen, Wilbert Bitter, Maikel Boot, J.J. Maaskant, Nanne J. Paauw, Theo Verboom, Riccardo Manganelli
Publikováno v:
van de Weerd, R, Boot, M, Maaskant, J, Sparrius, M, Verboom, T, van Leeuwen, L M, Burggraaf, M J, Paauw, N J, Dainese, E, Manganelli, R, Bitter, W, Appelmelk, B J & Geurtsen, J 2016, ' Inorganic Phosphate Limitation Modulates Capsular Polysaccharide Composition in Mycobacteria ', Journal of Biological Chemistry, vol. 291, no. 22, pp. 11787-11799 . https://doi.org/10.1074/jbc.M116.722454
Journal of Biological Chemistry, 291(22), 11787-11799. American Society for Biochemistry and Molecular Biology Inc.
van de Weerd, R, Boot, M, Maaskant, J, Sparrius, M, Verboom, T, van Leeuwen, L M, Burggraaf, M J, Paauw, N J, Dainese, E, Manganelli, R, Bitter, W, Appelmelk, B J & Geurtsen, J J G 2016, ' Inorganic phosphate limitation modulates capsular polysaccharide composition in Micobacteria. ', Journal of Biological Chemistry, vol. 291, no. 22, pp. 11787-11799 . https://doi.org/10.1074/jbc.M116.722454
Journal of Biological Chemistry, 291(22), 11787-11799. American Society for Biochemistry and Molecular Biology Inc.
van de Weerd, R, Boot, M, Maaskant, J, Sparrius, M, Verboom, T, van Leeuwen, L M, Burggraaf, M J, Paauw, N J, Dainese, E, Manganelli, R, Bitter, W, Appelmelk, B J & Geurtsen, J J G 2016, ' Inorganic phosphate limitation modulates capsular polysaccharide composition in Micobacteria. ', Journal of Biological Chemistry, vol. 291, no. 22, pp. 11787-11799 . https://doi.org/10.1074/jbc.M116.722454
Mycobacterium tuberculosis is protected by an unusual and highly impermeable cell envelope that is critically important for the successful colonization of the host. The outermost surface of this cell envelope is formed by capsular polysaccharides tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eec6e1f75e4a6433bfdb94e8e30d3b4d
https://europepmc.org/articles/PMC4882446/
https://europepmc.org/articles/PMC4882446/
Publikováno v:
Cold Spring Harbor perspectives in medicine, 5(3):a018580. Cold Spring Harbor Laboratory Press
van Leeuwen, L M, van der Sar, A M & Bitter, W 2015, ' Animal models of tuberculosis: Zebrafish ', Cold Spring Harbor perspectives in medicine, vol. 5, no. 3, a018580 . https://doi.org/10.1101/cshperspect.a018580
van Leeuwen, L M, van der Sar, A M & Bitter, W 2015, ' Animal models of tuberculosis: Zebrafish ', Cold Spring Harbor perspectives in medicine, vol. 5, no. 3, a018580 . https://doi.org/10.1101/cshperspect.a018580
Over the past decade the zebrafish (Danio rerio) has become an attractive new vertebrate model organism for studying mycobacterial pathogenesis. The combination of medium-throughput screening and real-time in vivo visualization has allowed new ways t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcbdf4b0aced12cd91a13bca444f5e23
https://research.vumc.nl/en/publications/c0235707-1b17-448f-85d8-b3c8241a4d80
https://research.vumc.nl/en/publications/c0235707-1b17-448f-85d8-b3c8241a4d80
Autor:
Esther J M, Stoop, Arun K, Mishra, Nicole N, Driessen, Gunny, van Stempvoort, Pascale, Bouchier, Theo, Verboom, Lisanne M, van Leeuwen, Marion, Sparrius, Susanne A, Raadsen, Maaike, van Zon, Nicole N, van der Wel, Gurdyal S, Besra, Jeroen, Geurtsen, Wilbert, Bitter, Ben J, Appelmelk, Astrid M, van der Sar
Publikováno v:
Cellular Microbiology
The causative agent of tuberculosis (TB), Mycobacterium tuberculosis, remains an important worldwide health threat. Although TB is one of the oldest infectious diseases of man, a detailed understanding of the mycobacterial mechanisms underlying patho