Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lisa-Marie Sturla"'
Autor:
Lisa-Marie Sturla, Ming Tong, Nick Hebda, Jinsong Gao, John-Michael Thomas, Mark Olsen, Suzanne M. de la Monte
Publikováno v:
Heliyon, Vol 2, Iss 12 (2016)
Background: Despite therapeutic advances, survival with glioblastoma multiforme (GBM) remains below 15 months from diagnosis due to GBM’s highly infiltrative nature which precludes complete surgical resection. Patient outcomes could potentially be
Externí odkaz:
https://doaj.org/article/2f58054f2fb14f30b6c7e4398c656dc1
Publikováno v:
Cancer Research. 83:1624-1624
Advanced or metastatic breast cancers represents a large patient population. Targeted therapies following hormonal or chemotherapeutic approaches offer some benefit. Subsequently, molecular profiling has identified over 100 mutations that render inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23d7373216e74bc04826811326ff3a5e
https://doi.org/10.1158/1538-7445.am2023-1624
https://doi.org/10.1158/1538-7445.am2023-1624
Autor:
Lillian M. Guenther, Scott L. Pomeroy, John Y.H. Kim, Christopher W. Cowan, Robert C. Castellino, Lisa-Marie Sturla
Publikováno v:
Cancer Research. 65:5683-5689
Expression of the neurotrophin-3 receptor, tyrosine kinase C (TrkC), is associated with favorable prognosis in medulloblastoma patients. This may be due to increased tumor apoptosis induced by TrkC activation. Neurotrophin-3/TrkC–induced apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb19f6e7dee4a24ed2da064c21ce5384
https://doi.org/10.1158/0008-5472.can-04-2283
https://doi.org/10.1158/0008-5472.can-04-2283
Autor:
Rebecca A. Betensky, Pablo Tamayo, John Y.H. Kim, Scott L. Pomeroy, Ana Fernandez-Teijeiro, Lisa Marie Sturla
Publikováno v:
Journal of Clinical Oncology. 22:994-998
Purpose Stratification of risk in patients with medulloblastoma remains a challenge. As clinical parameters have been proven insufficient for accurately defining disease risk, molecular markers have become the focus of interest. Outcome predictions o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ba4b52674e0eb9a9e37cc9306e66fae
https://doi.org/10.1200/jco.2004.03.036
https://doi.org/10.1200/jco.2004.03.036
Autor:
Ondrea Graves, John Y.H. Kim, Aaron L Nelson, Lisa Marie Sturla, Liliana Goumnerova, David H. Rowitch, Scott L. Pomeroy, Sibel A Algon, Rosalind A. Segal
Publikováno v:
Developmental Biology. 263:50-66
Medulloblastoma is a cerebellar tumor that can arise through aberrant activation of Sonic hedgehog (Shh) signaling, which normally regulates cerebellar granule cell proliferation. Mutations of the Shh receptor PATCHED (PTCH) are associated with medul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06ec683715d1d0130edea260e2bef07b
https://doi.org/10.1016/s0012-1606(03)00434-2
https://doi.org/10.1016/s0012-1606(03)00434-2
Autor:
Lisa-Marie Sturla, Scott L. Pomeroy
Publikováno v:
Pediatric Neurosurgery. 39:299-304
Molecular biological studies have created a new understanding of medulloblastomas, revealing key cell signaling pathways that promote tumor growth. These studies have identified molecular markers that can serve as prognostic indicators and which will
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e2d9e051c7e9ebc610e49b2792a70df
https://doi.org/10.1159/000075257
https://doi.org/10.1159/000075257
Autor:
Jill P. Mesirov, Liliana Goumnerova, Lisa Marie Sturla, Scott L. Pomeroy, Ching C. Lau, Tom Curran, Ryan Rifkin, David N. Louis, John Y.H. Kim, Shayan Mukherjee, Jaclyn A. Biegel, Gustavo Stolovitzky, Michelle Gaasenbeek, Andrea Califano, Todd R. Golub, Michael Angelo, Eric S. Lander, David Zagzag, Tomaso Poggio, James M. Olson, Jeffrey C. Allen, Margaret McLaughlin, Peter McL. Black, Pablo Tamayo, Cynthia Wetmore
Publikováno v:
Nature. 415:436-442
Embryonal tumours of the central nervous system (CNS) represent a heterogeneous group of tumours about which little is known biologically, and whose diagnosis, on the basis of morphologic appearance alone, is controversial. Medulloblastomas, for exam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb368e52e83cf4498cd7c03c165d124e
https://doi.org/10.1038/415436a
https://doi.org/10.1038/415436a
Publikováno v:
Tumor Dormancy, Quiescence, and Senescence, Volume 1 ISBN: 9789400759572
Resisting cellular senescence and becoming immortal is a pre-requisite step in the tumorigenic transformation of a cell. In this chapter we describe a novel mechanism by which inhibition of a key phosphatase can induce cellular senescence in the aggr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::229edb2730ecbdff206b929a9a305fcb
https://doi.org/10.1007/978-94-007-5958-9_21
https://doi.org/10.1007/978-94-007-5958-9_21
Autor:
Ming Tong, Nick Hebda, Lisa-Marie Sturla, Jin-Song Gao, Mark Olsen, John-Michael Thomas, Suzanne M. de la Monte
Publikováno v:
Heliyon
Heliyon, Vol 2, Iss 12 (2016)
Heliyon, Vol 2, Iss 12 (2016)
Background: Despite therapeutic advances, survival with glioblastoma multiforme (GBM) remains below 15 months from diagnosis due to GBM’s highly infiltrative nature which precludes complete surgical resection. Patient outcomes could potentially be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bfe931cea0a97b03f42981998537b05
https://doi.org/10.1016/j.heliyon.2016.e00203
https://doi.org/10.1016/j.heliyon.2016.e00203
Autor:
Mark H. Bilsky, R. Shane Tubbs, Jonas M. Sheehan, Osaama H. Khan, Scott L. Pomeroy, Katherine S. Panageas, David I. Sandberg, Lori A. McBride, John C. Wellons, W. Jerry Oakes, Terry Enno, Marc R. Del Bigio, Benson P. Yang, Brian H. Kushner, Mark M. Souweidane, Ken R. Winston, Paul M. Kanev, Jon D. Weingart, H. Haberl, W.R. Lanksch, L.M. Neumann, Nai-Kong V. Cheung, Maciej S. Lesniak, T. Kalbhenn, Benjamin S. Carson, Jack M. Klem, Jane E. Freeman, Matthew D. Smyth, Lisa-Marie Sturla, Kim Kramer, Michael P. LaQuaglia
Publikováno v:
Pediatric Neurosurgery. 39:345-347
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::099adf0fb49c67b01a1249dd6a8d4f44
https://doi.org/10.1159/000076381
https://doi.org/10.1159/000076381