Zobrazeno 1 - 10 of 16 pro vyhledávání: '"Lisa-Marie Pfeffermann"'
1
Akademický článek
Expression of HLA-DR by mesenchymal stromal cells in the platelet lysate era: an obsolete release criterion for MSCs?
Autor: Zyrafete Kuçi, Natascha Piede, Kathrin Vogelsang, Lisa-Marie Pfeffermann, Sibylle Wehner, Emilia Salzmann-Manrique, Miriam Stais, Hermann Kreyenberg, Halvard Bonig, Peter Bader, Selim Kuçi
Publikováno v: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background According to the definition of the International Society for Cell and Gene Therapy (ISCT), mesenchymal stromal cells (MSCs) do not express HLA-DR. This phenotypic marker as a release criterion for clinical use was established at a
Externí odkaz: https://doaj.org/article/778e9dd465974dbfb7bc2dc39a27d05c
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3
Akademický článek
Real-world data suggest effectiveness of the allogeneic mesenchymal stromal cells preparation MSC-FFM in ruxolitinib-refractory acute graft-versus-host disease
Autor: Halvard Bonig, Mareike Verbeek, Peter Herhaus, Krischan Braitsch, Gernot Beutel, Christoph Schmid, Nadine Müller, Gesine Bug, Michaela Döring, Arend von Stackelberg, Johanna Tischer, Francis Ayuk, Gerald Wulf, Udo Holtick, Lisa-Marie Pfeffermann, Bernd Jahrsdörfer, Hubert Schrezenmeier, Selim Kuci, Zyrafete Kuci, Anke Zens, Michael Tribanek, Robert Zeiser, Sabine Huenecke, Peter Bader
Publikováno v: Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Background Patients with steroid-refractory acute graft-versus-host disease (aGvHD) not tolerating/responding to ruxolitinib (RR-aGvHD) have a dismal prognosis. Methods We retrospectively assessed real-world outcomes of RR-aGvHD treated with
Externí odkaz: https://doaj.org/article/1942e01c115d422bbf46c4611ede54dd
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4
Akademický článek
Validation of an ICH Q2 Compliant Flow Cytometry-Based Assay for the Assessment of the Inhibitory Potential of Mesenchymal Stromal Cells on T Cell Proliferation
Autor: Natascha Piede, Melanie Bremm, Anne Farken, Lisa-Marie Pfeffermann, Claudia Cappel, Halvard Bonig, Theres Fingerhut, Laura Puth, Kathrin Vogelsang, Andreas Peinelt, Rolf Marschalek, Matthias Müller, Peter Bader, Zyrafete Kuçi, Selim Kuçi, Sabine Huenecke
Publikováno v: Cells, Vol 12, Iss 6, p 850 (2023)
Mesenchymal stromal cells (MSCs) have the potential to suppress pathological activation of immune cells and have therefore been considered for the treatment of Graft-versus-Host-Disease. The clinical application of MSCs requires a process validation
Externí odkaz: https://doaj.org/article/a7c755e7cf274e35b8578d2834c3ce95
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5
Akademický článek
Hematopoietic Stem Cell Transplantation Restores Naïve T-Cell Populations in Atm-Deficient Mice and in Preemptively Treated Patients With Ataxia-Telangiectasia
Autor: Ruth Duecker, Patrick C. Baer, Aileen Buecker, Sabine Huenecke, Lisa-Marie Pfeffermann, Ute Modlich, Shahrzad Bakhtiar, Peter Bader, Stefan Zielen, Ralf Schubert
Publikováno v: Frontiers in Immunology, Vol 10 (2019)
Background: Ataxia-telangiectasia (A-T) is a multisystem disorder with progressive cerebellar ataxia, immunodeficiency, chromosomal instability, and increased cancer susceptibility. Cellular immunodeficiency is based on naïve CD4+ and CD8+ T-cell ly
Externí odkaz: https://doaj.org/article/e8754e915039445e99bd174d0002e63f
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6
Akademický článek
Improving Clinical Manufacturing of IL-15 Activated Cytokine-Induced Killer (CIK) Cells
Autor: Melanie Bremm, Lisa-Marie Pfeffermann, Claudia Cappel, Verena Katzki, Stephanie Erben, Sibille Betz, Andrea Quaiser, Michael Merker, Halvard Bonig, Michael Schmidt, Thomas Klingebiel, Peter Bader, Sabine Huenecke, Eva Rettinger
Publikováno v: Frontiers in Immunology, Vol 10 (2019)
Cytokine-induced killer (CIK) cells are an immunotherapeutic approach to combat relapse following allogeneic hematopoietic stem cell transplantation (HSCT) in acute leukemia or myelodysplastic syndrome (MDS) patients. Prompt and sequential administra
Externí odkaz: https://doaj.org/article/2b410e20b4ca4cdc83f38cb8aef2ef96
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7
Akademický článek
The Phenotype and Functional Activity of Mesenchymal Stromal Cells in Pediatric Patients with Non-Malignant Hematological Diseases
Autor: Zyrafete Kuҫi, Christiane Jordan, Sibylle Wehner, Jan Sörensen, Andrea Jarisch, Emilia Salzmann-Manrique, Lisa-Marie Pfeffermann, Thomas Klingebiel, Peter Bader, Selim Kuҫi
Publikováno v: Cells, Vol 9, Iss 2, p 431 (2020)
As the biology of mesenchymal stromal cells (MSCs) in patients with non-malignant hematological diseases (NMHD) is poorly understood, in the current study we performed a basic characterization of the phenotype and functional activity of NMHD-MSCs. Bo
Externí odkaz: https://doaj.org/article/6432bdc507ea43d68b23340bfbe5be30
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10
Retargeting of NK-92 cells against high-risk rhabdomyosarcomas by means of an ERBB2 (HER2/Neu)-specific chimeric antigen receptor
Autor: Catrin Heim, Winfried S. Wels, Halvard Bonig, Peter Bader, Lisa-Marie Pfeffermann, Laura M Moser, Michael Merker, Leonie D H Gossel, Eva Rettinger, Thomas Klingebiel
Publikováno v: Cancers, Vol 13, Iss 1443, p 1443 (2021)
Cancers
Volume 13
Issue 6
Simple Summary In this study, we apply the ERBB2-chimeric antigen receptor (CAR)-modified natural killer (NK) cell line NK-92 (NK-92/5.28.z), a well-defined, good manufacturing practice (GMP)-compliant, third-party, off-the-shelf immune effector cell
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::706b503fc5b0b4b67ad4170ac34a1e73
http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/62465
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