The kinetochore prevents centromere-proximal crossover recombination during meiosis

Autor: Nadine Vincenten, Lisa-Marie Kuhl, Isabel Lam, Ashwini Oke, Alastair RW Kerr, Andreas Hochwagen, Jennifer Fung, Scott Keeney, Gerben Vader, Adèle L Marston

Publikováno v: eLife, Vol 4 (2015)

During meiosis, crossover recombination is essential to link homologous chromosomes and drive faithful chromosome segregation. Crossover recombination is non-random across the genome, and centromere-proximal crossovers are associated with an increase

Externí odkaz: https://doaj.org/article/d9545cc4fea14f88afad30f21144ad85

A dCas9-based system identifies a central role for Ctf19 in kinetochore-derived suppression of meiotic recombination

Autor: Vasso Makrantoni, Adele L. Marston, Gerben Vader, Lisa Marie Kuhl, Animish N. Vaze, Sarah Recknagel

Publikováno v: Genetics, 216(2), 395-408. Genetics Society of America
Genetics
Kuhl, L M, Makrantoni, V, Recknagel, S, Vaze, A N, Marston, A L & Vader, G 2020, ' A dCas9-based system identifies a central role for Ctf19 in kinetochore-derived suppression of meiotic recombination ', Genetics, vol. 216, no. 2, pp. 395-408 . https://doi.org/10.1534/genetics.120.303384

A dCas9-based system is developed to query the regulation of kinetochore-driven meiotic recombinational control....
In meiosis, crossover (CO) formation between homologous chromosomes is essential for faithful segregation. However, misplaced mei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10fcf395a3b637103a5e9db83a50c0d9
https://research.vumc.nl/en/publications/e9eee7dd-da13-424c-9d14-1e45e06c9463

The kinetochore prevents centromere-proximal crossover recombination during meiosis

Autor: Gerben Vader, Lisa Marie Kuhl, Scott Keeney, Andreas Hochwagen, Jennifer C. Fung, Alastair R.W. Kerr, Isabel Lam, Nadine Vincenten, Ashwini Oke, Adele L. Marston

Publikováno v: eLife
Vincenten, N, Kuhl, L M, Lam, I, Oke, A, Kerr, A R W, Hochwagen, A, Fung, J, Keeney, S, Vader, G & Marston, A L 2015, ' The kinetochore prevents centromere-proximal crossover recombination during meiosis ', eLIFE, vol. 4, e10850 . https://doi.org/10.7554/eLife.10850
eLife, Vol 4 (2015)

During meiosis, crossover recombination is essential to link homologous chromosomes and drive faithful chromosome segregation. Crossover recombination is non-random across the genome, and centromere-proximal crossovers are associated with an increase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b248a56df82faa8266e74f2308bc35d9
http://europepmc.org/articles/PMC4749563