Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lisa Wise-Milestone"'
Autor:
Victor C. K. Lo, Cari M. Whyne, Brian C. Wilson, Albert Yee, Margarete K. Akens, Lisa Wise-Milestone
Publikováno v:
Journal of Orthopaedic Research. 31:1398-1405
Photodynamic therapy (PDT) has been shown to ablate tumors within vertebral bone and yield short-term improvements in vertebral architecture and biomechanical strength, in particular when combined with bisphosphonate (BP) treatment. Longer-term outco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ee16c560e981814a9813362e7411f31
https://doi.org/10.1002/jor.22373
https://doi.org/10.1002/jor.22373
Publikováno v:
Medical Physics. 39:2848-2853
Purpose: Multimodal microimaging in preclinical models is used to examine the effect of spinal metastases on bony structure; however, the evaluation of tumor burden and its effect on microstructure has thus far been mainly qualitative or semiquantita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1153054c663e407f9c6a5b31ca95ee5
https://doi.org/10.1118/1.3703590
https://doi.org/10.1118/1.3703590
Autor:
Albert Yee, Lisa Wise-Milestone, Margarete K. Akens, Cari M. Whyne, Victor C. K. Lo, Brian C. Wilson
Publikováno v:
Breast Cancer Research and Treatment. 133:899-908
The widespread use of systemic and local therapies aimed at spinal metastatic lesions secondary to breast cancer has increased the incidence of mixed osteolytic/osteoblastic patterns of bony disease. The complex structure of these lesions requires no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45cf7622e34e8f054a18f1c84c13e9bc
https://doi.org/10.1007/s10549-011-1854-y
https://doi.org/10.1007/s10549-011-1854-y
Autor:
Cari M. Whyne, Lisa Wise-Milestone, Shane Burch, Margarete K. Akens, Emily Won, Albert Yee, Brian C. Wilson
Publikováno v:
Breast Cancer Research and Treatment. 124:111-119
Breast cancer patients commonly develop metastases in the spine, which compromises its mechanical stability and can lead to skeletal related events. The current clinical standard of treatment includes the administration of systemic bisphosphonates (B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80fb2cfc9bfa5b252a8f048c5abcf544
https://doi.org/10.1007/s10549-009-0712-7
https://doi.org/10.1007/s10549-009-0712-7
Autor:
Lisa Wise-Milestone, Emily Won, Carolyn Niu, Margarete K. Akens, Aimee Theriault, Albert Yee, Victor C. K. Lo, Shane Burch, Stuart K. Bisland, Brian C. Wilson, Cari M. Whyne
Publikováno v:
SPIE Proceedings.
Metastatic cancer causes the majority of tumors in bone, most frequently detected in the spinal column. Skeletal complications cause pain and neurologic impairment. Photodynamic therapy (PDT) has been used to treat a variety of cancers. Minimally inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e7dcaa1b19abbe1326864b512771838
https://doi.org/10.1117/12.2019796
https://doi.org/10.1117/12.2019796
Autor:
Cari M. Whyne, Lisa Wise-Milestone, Margarete K. Akens, Joerg Schwock, Emily Won, Brian C. Wilson, Albert Yee
Publikováno v:
Photodiagnosis and photodynamic therapy. 11(3)
Summary Background Photodynamic therapy (PDT), a non-ionizing, minimally invasive drug-light treatment, has recently been shown to successfully ablate tumor within rat vertebrae with concurrent improvements in bone strength and architecture. The bisp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::504e513b81469f096f2ffd0ba15639d3
https://pubmed.ncbi.nlm.nih.gov/25176573
https://pubmed.ncbi.nlm.nih.gov/25176573
Publikováno v:
Medical physics. 39(5)
Multimodal microimaging in preclinical models is used to examine the effect of spinal metastases on bony structure; however, the evaluation of tumor burden and its effect on microstructure has thus far been mainly qualitative or semiquantitative. Qua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3cb0bd2126f84bf7078d6684d8a873b0
https://pubmed.ncbi.nlm.nih.gov/22559657
https://pubmed.ncbi.nlm.nih.gov/22559657
Autor:
Victor C K, Lo, Margarete K, Akens, Lisa, Wise-Milestone, Albert J M, Yee, Brian C, Wilson, Cari M, Whyne
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 31(9)
Photodynamic therapy (PDT) has been shown to ablate tumors within vertebral bone and yield short-term improvements in vertebral architecture and biomechanical strength, in particular when combined with bisphosphonate (BP) treatment. Longer-term outco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f1f84dc2cb146d548d96dd73dbfe97ba
https://pubmed.ncbi.nlm.nih.gov/23625821
https://pubmed.ncbi.nlm.nih.gov/23625821
Autor:
Juan Chen, Lisa Wise-Milestone, Margarete K. Akens, Gang Zheng, Brian C. Wilson, Tracy W. Liu
Publikováno v:
Biomedical Optics and 3-D Imaging.
We demonstrate the metastatic-specific activation of photodynamic molecular beacons by matrix metalloproteinases as a useful image-guidance tool with an unprecedented level of PDT selectivity for the therapeutic management of breast cancer spinal met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a69797c3552a14894d6e023dd9a1685
https://doi.org/10.1364/biomed.2012.bsu3a.83
https://doi.org/10.1364/biomed.2012.bsu3a.83
Autor:
Cari M. Whyne, Margarete K. Akens, Thomas J. Rosol, Seyed-Parsa Hojjat, Lisa Wise-Milestone, Marc D. Grynpas
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 30(5)
Spinal metastases often show mixed areas of enhanced (osteoblastic) bone growth adjacent to areas of thinning (osteolytic) bone. This study aims to quantitatively characterize bone quality and tumor burden within a new rat model of mixed osteolytic/o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c87d9b4ba0298bfcc5335871cb78a03
https://pubmed.ncbi.nlm.nih.gov/22025272
https://pubmed.ncbi.nlm.nih.gov/22025272