Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Lisa Williams-Simons"'
Autor:
Aniket V Gore, Brett Athans, James R Iben, Kristin Johnson, Valya Russanova, Daniel Castranova, Van N Pham, Matthew G Butler, Lisa Williams-Simons, James T Nichols, Erica Bresciani, Bejamin Feldman, Charles B Kimmel, Paul P Liu, Brant M Weinstein
Publikováno v:
eLife, Vol 5 (2016)
During embryonic development, cell type-specific transcription factors promote cell identities, while epigenetic modifications are thought to contribute to maintain these cell fates. Our understanding of how genetic and epigenetic modes of regulation
Externí odkaz:
https://doaj.org/article/d49e94f6588e42b886215463aa573ada
Autor:
Paul P. Liu, Erica Bresciani, Van N. Pham, Brett Athans, Daniel Castranova, Brant M. Weinstein, Matthew G. Butler, Aniket V. Gore, Kristin Johnson, Bejamin Feldman, Lisa Williams-Simons, James R. Iben, James T. Nichols, Valya R. Russanova, Charles B. Kimmel
Publikováno v:
eLife
eLife, Vol 5 (2016)
eLife, Vol 5 (2016)
During embryonic development, cell type-specific transcription factors promote cell identities, while epigenetic modifications are thought to contribute to maintain these cell fates. Our understanding of how genetic and epigenetic modes of regulation
Autor:
Van N. Pham, Bejamin Feldman, Kristin Johnson, James R. Iben, Charles B. Kimmel, Valya R. Russanova, Paul P. Liu, Matthew G. Butler, Erica Bresciani, Aniket V. Gore, Daniel Castranova, James T. Nichols, Brett Athans, Lisa Williams-Simons, Brant M. Weinstein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22f8796b16a9412b6666a85c14d7f91c
https://doi.org/10.7554/elife.11813.023
https://doi.org/10.7554/elife.11813.023
Publikováno v:
Molecular Endocrinology. 22:380-387
Carney complex (CNC) is an inherited neoplasia syndrome characterized by spotty skin pigmentation, myxomas, endocrine tumors, and schwannomas. Among the endocrine tumors that comprise the syndrome, GH-producing pituitary tumors are seen in approximat
Publikováno v:
genesis. 46:37-42
Tissue-specific expression of the Cre recombinase is a well-established genetic tool to analyze gene function in specific tissues and cell types. In this report, we describe the generation of a new transgenic line that expresses Cre under the control
Autor:
Madhulika Srivastava, Alexander Grinberg, Sandra Hsieh, Karl Pfeifer, Sing-Ping Huang, Lisa Williams-Simons
Publikováno v:
Genes & Development. 14:1186-1195
H19 and Igf2 are expressed in a monoallelic fashion from the maternal and paternal chromosomes, respectively. A region upstream of H19 has been shown to regulate such imprinted expression of both genes in cis. We have taken advantage of aloxP/cre rec
Publikováno v:
Proceedings of the National Academy of Sciences. 92:6142-6146
If deprived of wild-type p53 function, the body loses a guardian that protects against cancer. Restoration of p53 function has, therefore, been proposed as a means of counteracting oncogenesis. This concept of therapy requires prior knowledge with re
Publikováno v:
Transgenic research. 15(2)
The urokinase-type plasminogen activator (uPA) is a secreted, inducible serine protease implicated in extracellular proteolysis and tissue remodeling. Here we detected uPA mRNA through in situ hybridization in developing molar and incisor teeth of no
Autor:
Lisa Williams-Simons, Uwe W. Rothenpieler, Gregory R. Dressler, Larry T. Patterson, J. Erby Wilkinson, Heiner Westphal
Publikováno v:
Nature. 362:65-67
The Pax genes comprise a family of transcription factors active in specific tissues during embryonic development and are associated with at least three developmental mutations in mouse and man. In the developing kidney, Pax-2 is expressed in the indu
Publikováno v:
Oncogene. 14(25)
We have studied the concerted action of factors that influence the balance between cell proliferation and cell death in the developing lens of transgenic mice. We show that a human papillomavirus type 18 (HPV18) E6/E7 transgene that predominantly exp