Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Lisa Wendt"'
Autor:
Lisa Wendt, Matthew J. Pickin, Bianca S. Bodmer, Sven Reiche, Lucie Fénéant, Julia E. Hölper, Walter Fuchs, Allison Groseth, Thomas Hoenen
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
N6-methyladenosine (m6A) is one of the most abundant modifications of cellular RNA, where it serves various functions. m6A methylation of many viral RNA species has also been described; however, little is known about the m6A epitranscriptome of haemo
Externí odkaz:
https://doaj.org/article/62c5266ddb584950a551e67cafce10d7
Autor:
Bianca S. Bodmer, Melina Vallbracht, Dmitry S. Ushakov, Lisa Wendt, Petr Chlanda, Thomas Hoenen
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
Viral RNA synthesis of several non-segmented, negative-sense RNA viruses (NNSVs) takes place in inclusion bodies (IBs) that show properties of liquid organelles, which are formed by liquid–liquid phase separation of scaffold proteins. It is believe
Externí odkaz:
https://doaj.org/article/0710fdb8a91d42d8bb641e184a8ff62c
Autor:
Patrick Bohn, Irke Waßmann, Lisa Wendt, Anne Leske, Thomas Hoenen, Birke A Tews, Allison Groseth
Publikováno v:
PLoS Pathogens, Vol 19, Iss 1, p e1011049 (2023)
The arenavirus nucleoprotein (NP) plays an important role in the virus' ability to block interferon (IFN) production, and its exonuclease function appears to contribute to this activity. However, efforts to analyze this contribution are complicated b
Externí odkaz:
https://doaj.org/article/e5d7719fe8464b13924a2921d1d19290
Autor:
Michelle Hwang, Kelsey Wilson, Lisa Wendt, Joshua Pohlman, Emily Densmore, Caitlin Kaeppler, Kyle Van Arendonk, Sarah Yale
Publikováno v:
BMC Pediatrics, Vol 21, Iss 1, Pp 1-5 (2021)
Abstract Background Abdominal pain and other gastrointestinal symptoms are common presenting features of multisystem inflammatory syndrome in children (MIS-C) and can overlap with infectious or inflammatory abdominal conditions, making accurate diagn
Externí odkaz:
https://doaj.org/article/aaad7f86a66345f4b476b3139b40b71b
Autor:
Scott Martin, Abhilash I. Chiramel, Marie Luisa Schmidt, Yu-Chi Chen, Nadia Whitt, Ari Watt, Eric C. Dunham, Kyle Shifflett, Shelby Traeger, Anne Leske, Eugen Buehler, Cynthia Martellaro, Janine Brandt, Lisa Wendt, Andreas Müller, Stephanie Peitsch, Sonja M. Best, Jürgen Stech, Stefan Finke, Angela Römer-Oberdörfer, Allison Groseth, Heinz Feldmann, Thomas Hoenen
Publikováno v:
Genome Medicine, Vol 10, Iss 1, Pp 1-14 (2018)
Abstract Background The 2014–2016 Ebola virus (EBOV) outbreak in West Africa highlighted the need for improved therapeutic options against this virus. Approaches targeting host factors/pathways essential for the virus are advantageous because they
Externí odkaz:
https://doaj.org/article/de07dea36f0548debf36fe428049f3e0
Autor:
Julia E. Hölper, Finn Grey, John Kenneth Baillie, Tim Regan, Nicholas J. Parkinson, Dirk Höper, Thiprampai Thamamongood, Martin Schwemmle, Katrin Pannhorst, Lisa Wendt, Thomas C. Mettenleiter, Barbara G. Klupp
Publikováno v:
Viruses, Vol 13, Iss 8, p 1574 (2021)
Herpesviruses are large DNA viruses, which encode up to 300 different proteins including enzymes enabling efficient replication. Nevertheless, they depend on a multitude of host cell proteins for successful propagation. To uncover cellular host facto
Externí odkaz:
https://doaj.org/article/a3f7112d71f844f6b3eef668d19d5721
Publikováno v:
Cells, Vol 9, Iss 5, p 1126 (2020)
Ebola virus (EBOV) is a zoonotic pathogen causing severe hemorrhagic fevers in humans and non-human primates with high case fatality rates. In recent years, the number and extent of outbreaks has increased, highlighting the importance of better under
Externí odkaz:
https://doaj.org/article/d9baeee412524508ab8a40e6b6fdb9b6
Autor:
Lisa Wendt, Janine Brandt, Bianca S. Bodmer, Sven Reiche, Marie Luisa Schmidt, Shelby Traeger, Thomas Hoenen
Publikováno v:
Cells, Vol 9, Iss 1, p 187 (2020)
Ebola virus (EBOV) causes severe outbreaks of viral hemorrhagic fever in humans. While virus-host interactions are promising targets for antivirals, there is only limited knowledge regarding the interactions of EBOV with cellular host factors. Recent
Externí odkaz:
https://doaj.org/article/d07a380e6e7243358b6475b881124802
Autor:
Shangfan Hu, Yoko Fujita-Fujiharu, Yukihiko Sugita, Lisa Wendt, Yukiko Muramoto, Masahiro Nakano, Thomas Hoenen, Takeshi Noda
Publikováno v:
PNAS Nexus. 2
Lloviu virus (LLOV) is a novel filovirus detected in Schreiber’s bats in Europe. The isolation of the infectious LLOV from bats has raised public health concerns. However, the virological and molecular characteristics of LLOV remain largely unknown
Autor:
Lisa Wendt, Janine Brandt, Dmitry S. Ushakov, Bianca S. Bodmer, Matthew J. Pickin, Allison Groseth, Thomas Hoenen
Publikováno v:
J Virol
Many negative-sense RNA viruses, including the highly pathogenic Ebola virus (EBOV), use cytoplasmic inclusion bodies (IBs) for viral RNA synthesis. However, it remains unclear how viral mRNAs are exported from these IBs for subsequent translation. W