Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lisa Vawter"'
Autor:
Henry M. Sarau, Kay Murphy, Piers C. Emson, Darren J. Moore, Hinayana Bawagan, Jon K. Chambers, Ping Tsui, Shelagh Wilson, Katie Freeman, Sajda Naheed, Robert S. Ames, George P. Livi, Pamela Lane, Lisa Vawter, Nicole C. Herrity
Publikováno v:
Genomics. 78:124-128
It has recently been shown that UDP-glucose is a potent agonist of the orphan G-protein-coupled receptor (GPCR) KIAA0001. Here we report cloning and analysis of the rat and mouse orthologs of this receptor. In accordance with GPCR nomenclature, we ha
Publikováno v:
Journal of Computational Biology. 7:59-70
This paper introduces a novel class of tree comparison problems strongly motivated by an important and cost intensive step in drug discovery pipeline viz., mapping cell bound receptors to the ligands they bind to and vice versa. Tree comparison studi
Publikováno v:
Lecture Notes in Computer Science ISBN: 9783540442110
WABI
WABI
We address the problem of estimating the degree to which the evolutionary history of a set of molecular sequences violates a strong molecular clock hypothesis.We quantify this deviation formally, by defining the "stretch" of a model tree with respect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::478ec8db8516dd6e637a5a452fe4f7f2
https://doi.org/10.1007/3-540-45784-4_22
https://doi.org/10.1007/3-540-45784-4_22
Publikováno v:
SPIE Proceedings.
Phylogenies (that is, tree-of-life relationships) derived from gene order data may prove crucial in answering some fundamental open questions in biomolecular evolution. Real-world interest is strong in determining these relationships. For example, ph
Autor:
Mcmillan Lynette Jane, James J. Foley, Paul R. Murdock, Philip G. Szekeres, Shelagh Wilson, Andrew J. Murphy, Sajda Naheed, Claire Scott, George P. Livi, Jon K. Chambers, Derk J. Bergsma, Emir Duzic, Katie Freeman, John J. Trill, Henry M. Sarau, Christine Klein, Paul H. Taylor, Macdonald Lynn, Nambi Aiyar, Ann M. Swift, Robert S. Ames, Jeanette M. Watson, Yuan Zhu, Guillaume Hervieu, Lisa Vawter, Megan M. McLaughlin
Publikováno v:
The Journal of biological chemistry. 275(15)
Uridine 5′-diphosphoglucose (UDP-glucose) has a well established biochemical role as a glycosyl donor in the enzymatic biosynthesis of carbohydrates. It is less well known that UDP-glucose may possess pharmacological activity, suggesting that a rec
Autor:
Nabil Elshourbagy, Jeffrey L. Mooney, Mcmillan Lynette Jane, Hsiao-Ling Wu, Sharon Butler, Angela M. Smith, Laura R. Fitzgerald, Shelagh Wilson, Philip G. Szekeres, Derk J. Bergsma, Jane Miller, Gillian I. Rennie, Alison I. Muir, Lisa D. Spinage, Stephanie E. Guerrera, Jon K. Chambers, Lisa Vawter, Paul R. Murdock
Publikováno v:
The Journal of biological chemistry. 275(27)
Neuromedins are a family of peptides best known for their contractile activity on smooth muscle preparations. The biological mechanism of action of neuromedin U remains unknown, despite the fact that the peptide was first isolated in 1985. Here we sh